ISSN:
1573-8221
Keywords:
irradiation
;
adenylate cyclase
;
phosphodiesterase
;
cyclic AMP level
;
lymphocytes
Source:
Springer Online Journal Archives 1860-2000
Topics:
Biology
,
Medicine
Notes:
Abstract In the early periods after irradiation of muscles in a dose of 800 rad changes in the activity of the enzymes of cyclic AMP metabolism are found in the lymphocytes of the spleen and thymus. The postradiation disturbance of the relative activities of these enzymes leads to changes in the steady-state intracellular cyclic AMP concentration. It is also shown that irradiation reduces the ability of lymphocytes to respond to isoproterenol by accumulating cyclic AMP.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF00800112
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