Publication Date:
1983-04-22
Description:
Electric fields were found to deform sickled erythrocytes. When the intensity of applied fields exceeded a threshold value, sickled erythrocytes transformed into a spherical shape. Prolonged application of the field usually caused hemolysis of erythrocytes. Deformation of red blood cells could be partly reversed if the field was turned off at an early stage. The cause of desickling may be the interaction of the field with the erythrocyte membrane and also with gelled intracellular hemoglobin S molecules.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Takashima, S -- Asakura, T -- HL-18226/HL/NHLBI NIH HHS/ -- HL-20750/HL/NHLBI NIH HHS/ -- New York, N.Y. -- Science. 1983 Apr 22;220(4595):411-3.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/6836283" target="_blank"〉PubMed〈/a〉
Keywords:
Anemia, Sickle Cell/*radiotherapy
;
Erythrocyte Membrane/physiology
;
Erythrocytes/*radiation effects
;
Humans
;
Membrane Potentials/radiation effects
;
*Radio Waves
Print ISSN:
0036-8075
Electronic ISSN:
1095-9203
Topics:
Biology
,
Chemistry and Pharmacology
,
Computer Science
,
Medicine
,
Natural Sciences in General
,
Physics
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