ISSN:
1572-901X
Source:
Springer Online Journal Archives 1860-2000
Topics:
Chemistry and Pharmacology
Notes:
Summary The kinetics of the reaction of chromium(III) and L-hydroxyproline have been investigated under varying conditions of [substrate], [ligand], [H+], ionic strength, % ethanol and temperature by spectrophotometry. The observed pseudo-first-order-rate constants were found to be expressed by the following equation. $$k_{obs} = \frac{{(k_1 K_a K_1 [H^ + ] + k_2 K_a K'_a K_2 )[Hydroxyproline]_T }}{\begin{gathered} [H^ + ]^2 + [H^ + ]K_a + [H^ + ]K'_a + K_a K'_a + \hfill \\ (K_a K_1 [H^ + ] + K_a K'_a K_2 )[Hydroxyproline]_T \hfill \\ \end{gathered} }$$ A mechanism has been proposed. The anation rate constants (k1, k2) and outer-sphere-association constants (K1, K2) and their thermodynamic parameters have been calculated using the Eyring equation. The reaction of [Cr(H2O)6]3+ follows an associative (Ia) path, whereas that of [Cr(H2O)5OH]2+ follows a dissociative (Id) path. The results are compared with related published data.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF01171644
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