ISSN:
0021-9304
Keywords:
Chemistry
;
Polymer and Materials Science
Source:
Wiley InterScience Backfile Collection 1832-2000
Topics:
Medicine
,
Technology
Notes:
Ultra low temperature isotropic (ULTI) carbon-coated polyester suture material was evaluated histologically and mechanically in dogs. These results were compared to those obtainedfor uncoated polyester and polybutylate coated polyester. The suture materials were used in therepair of the surgically incised medical collateral ligament and subcutaneous tissues to evaluate the potential of the carbon-coated system for ligamentous repairs. Following surgery, the dogs were sacrificed at periods of 1-48 weeks postoperatively for evaluation of tissue biocompatibility and mechanical strength of the materials. The polybutylate-coated polyester suture broke at lower force levels than did comparable sizes of uncoated or carbon-coated polyester. All three types showed a high retention (〉98%) of mechanical strength at 48weeks, often exhibiting an increase in tensile strength due to tissue ingrowth. The histologic response to carbon-coated polyester was equal to or better than the response to either the uncoated polyester or polybutylate-coated polyester. A greater degree of tissue growth into the carbon-coated material was evident at most time periods following an initial acute inflammatory response which was also present in the other materials.
Additional Material:
11 Ill.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1002/jbm.820200909
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