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In vivo histologic and biomechanical characterization of a biodegradable particulate composite bone cement (1989)

Gerhart, Tobin N. ; Renshaw, Andrew A. ; Miller, Richard L. ; [et al.]

Hoboken, NJ : Wiley-Blackwell

Journal of Biomedical Materials Research 23 (1989), S. 1-16

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ISSN: 0021-9304

Keywords: Chemistry ; Polymer and Materials Science

Source: Wiley InterScience Backfile Collection 1832-2000

Topics: Medicine , Technology

Notes: A biodegradable particulate composite bone cement consisting of a crosslinked gelatin matrix and tricalcium phosphate particles was implanted intraosseously in rabbits for up to 12 weeks. Cured cylindrical implants were inserted in holes drilled in the proximal tibial metaphysis. Sequential fluorochrome labeling and radiographs were done, and specimens were processed for decalcified and nondecalcified histology. At 4 weeks, the cross-sectional diameter of the implant was slightly greater than at implantation. There was considerable dissolution of the matrix and some new bone ingrowth. At 12 weeks, the diameter was reduced to half the original diameter and bone had grown throughout the matrix. In the distal femur, freshly mixed cement was used to stabilize an osteochondral fracture. Mechanical testing of the cement-stabilized fracture revealed a decrease in compressive strength and modulus at 4 weeks followed by an increase to greater than initial values at 12 weeks. Over time, the osteochondral fragment subsided into the underlying cement, but the subsidence did not correlate with mechanical strength. This osteochondral fracture model permits measurement of the overall material properties of a cement simultaneously weakened by resorption and reinforced by ingrowing bone.

Additional Material: 10 Ill.

Type of Medium: Electronic Resource

URL: http://dx.doi.org/10.1002/jbm.820230102

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A monomeric plasticizer for high temperature applications (1986)

Payne, Marc T. ; Renshaw, James T.

Brookfield, Conn. : Wiley-Blackwell

Journal of Vinyl and Additive Technology 8 (1986), S. 49-54

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ISSN: 0193-7197

Keywords: Chemistry ; Chemical Engineering

Source: Wiley InterScience Backfile Collection 1832-2000

Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics , Process Engineering, Biotechnology, Nutrition Technology

Notes: The results of this study demonstrate that high molecular weight and predominantly linear diundecyl phthalate (DUP) provide improved performance properties and cost savings when used as a partial or total replacement for trimellitate plasticizers in critical applications such as vinyl electrical insulations and crashpad covers. DUP is shown to be a permanent and stable plasticizer with a high efficiency in improving low-temperature flexibility of formulated vinyls.

Additional Material: 1 Ill.