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All Library Books, journals and Electronic Records Telegrafenberg

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  • Springer  (499)
  • American Institute of Physics  (127)
  • National Academy of Sciences  (40)
  • American Chemical Society (ACS)
  • 1985-1989  (666)
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  • 1
    ISSN: 1432-1041
    Keywords: doxazosin ; hypertension ; alpha1-adrenoceptor inhibitor ; elderly patients ; pharmacokinetics
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology , Medicine
    Notes: Summary The α1-adrenoceptor antagonist doxazosin has been compared with placebo in 40 elderly hypertensive patients (mean age 71.4 years). At the end of 10 weeks once daily treatment with doxazosin the mean 24-h post-dose changes in standing and supine blood pressure compared with placebo were −6.9/−5.6 mmHg (systolic/diastolic) and −6.2/−5.5 mmHg respectively. The reductions in standing and supine diastolic blood pressures were statistically significant compared with placebo. At the end of treatment steady-state pharmacokinetics were evaluated in 18 patients. The plasma elimination half-life during the dose interval in these patients was 16.1 h (range 10.1–27.1 h) and the median time to peak plasma concentration was 3 h (range 1–4 h). One patient was withdrawn because of adverse effects (headache, weakness, and sweating) during doxazosin treatment. Once daily doxazosin reduced diastolic blood pressure and was well tolerated in these elderly hypertensive patients.
    Type of Medium: Electronic Resource
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  • 2
    Publication Date: 1988-01-01
    Print ISSN: 0031-6970
    Electronic ISSN: 1432-1041
    Topics: Chemistry and Pharmacology , Medicine
    Published by Springer
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  • 3
    Publication Date: 1988-02-01
    Print ISSN: 0024-4201
    Electronic ISSN: 1558-9307
    Topics: Biology , Chemistry and Pharmacology
    Published by Springer
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  • 4
    Electronic Resource
    Electronic Resource
    Springer
    Bulletin of mathematical biology 51 (1989), S. 715-730 
    ISSN: 1522-9602
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Mathematics
    Notes: Abstract In a separate paper, we developed a mathematical model describing HIV infection and used it to suggest experiments for quantifying characteristic viral parameters. In this paper we generalize the model to any well-mixed assay system. We also present complete and rigorous derivations of fundamental results needed for the design and analysis of HIV infectivity assays. The model is applicable to infectious agents with multiple receptors for their target cell (e.g. HIV, Epstein-Barr virus and Plasmodium), and to blockers (both reversible and irreversible), as long as blocker and target cells are the same diffusion compartment.
    Type of Medium: Electronic Resource
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  • 5
    ISSN: 1476-5535
    Keywords: Metabolism ; Acetate ; Alginate ; Carbon balance
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: Summary Some metabolic properties of both suspended and immobilized aerobically and anaerobically growingEscherichia coli cells were investigated. Metabolic activity was found to be substantially different whenE. coli cells were immobilized in alginate. Cells grown immobilized in alginate, and then released from the gel, synthesized 1.6 (aerobic growth) and 4.9 (anaerobic growth) times as much β-galactosidase per cell in response to induction as did suspended cells. Under both aerobic and anaerobic conditions, the cell yield from glycerol for immobilized cells was half that for suspended cells. At specific growth rates that were not significantly different from those of suspended cells, immobilized cells consumed glycerol at twice the rate of suspended cells. Immobilized cells produced elevated quantities of acetate, pyruvate, and lactate. Interpretation of these findings is discussed in terms of the kinetics of energy metabolism and the regulation of inducible protein synthesis inE. coli.
    Type of Medium: Electronic Resource
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  • 6
    Electronic Resource
    Electronic Resource
    Springer
    Journal of industrial microbiology and biotechnology 4 (1989), S. 109-120 
    ISSN: 1476-5535
    Keywords: Ground water ; Biodegradation ; Hydrocarbon ; Adaptation ; Subsurface ; Creosote ; Microorganism
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: Summary The microbial ecology of pristine, slightly contaminated, and heavily contaminated subsurface materials, and four subsurface materials on the periphery of the plume at an abandoned creosote waste site was investigated. Except for the unsaturated zone of the heavily contaminated material, mineralization of glucose (13.5 ppb) indicated a metabolically active microflora in all subsurface materials. However, mineralization (〈40%) of naphthalene, phenanthrene, and 2-methylnaphthalene was observed in contaminated material and material from the periphery of the plume, but not in pristine material. Pentachlorophenol was mineralized in material from the periphery of the plume. Inorganic and organic nutrient amendments and changes in pH and temperature did not increase the extent of mineralization of the aromatic compounds. An array of organic compounds found in creosote were biotransformed in contaminated ground water; however some compounds were still detected after 7 months of incubation. The data suggest that the subsurface microflora in slightly and heavily contaminated subsurface materials and materials from the periphery of the plume has adapted to degrade many compounds found in creosote.
    Type of Medium: Electronic Resource
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  • 7
    Electronic Resource
    Electronic Resource
    Springer
    Journal of applied electrochemistry 17 (1987), S. 925-935 
    ISSN: 1572-8838
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology , Electrical Engineering, Measurement and Control Technology
    Notes: Abstract The purpose of this paper is to address the problem of galvanostatic operation of irreversible electrochemical series and parallel reactions. The application of a constant current is known to be the preferred mode of industrial, electrochemical reactor operation. However, variations in product yields and current efficiencies are not easily predicted for this operational mode, except for simple limiting situations. By numerical solution of the governing first-order differential equations for batch and plug flow reactions, product yields have been predicted as a function of reactant conversion for a wide range of kinetic parameters. The effect of mass transport limitations and solvent decomposition is an integral feature of the analysis. The performance characteristics obtained give a general description of the behaviour of most series and parallel electrochemical reactions. The possibility of a kinetic analysis of these electrochemical reactions from experimental yield data has been broadly demonstrated using published experimental data.
    Type of Medium: Electronic Resource
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  • 8
    Electronic Resource
    Electronic Resource
    Springer
    Journal of applied electrochemistry 17 (1987), S. 329-339 
    ISSN: 1572-8838
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology , Electrical Engineering, Measurement and Control Technology
    Notes: Abstract A mathematical model of a reaction scheme for the electrohydrodymerization of acrylonitrile to adiponitrile in a loop reactor is presented. This model, which is based on a plug flow reactor with a recycle loop and continuous removal of product, is used to simulate steady-state operation at various operating conditions. The effect of flowrate, current density and mass transport are investigated in terms of their effect on product distributions and selectivity. Overall, the reaction model deals with the formation of five products from the cathodic reactions.
    Type of Medium: Electronic Resource
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  • 9
    Electronic Resource
    Electronic Resource
    Springer
    Journal of insect behavior 2 (1989), S. 133-137 
    ISSN: 1572-8889
    Keywords: paternal care ; reproductive success ; Nicrophorus ; burying beetle ; brood care
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Type of Medium: Electronic Resource
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  • 10
    ISSN: 1572-8889
    Keywords: Orthoptera ; Haglidae ; Cyphoderris ; acoustic ; mate choice ; mating success ; nuptial feeding ; spermatophylax
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Abstract Male reproductive behavior in the relict flightless haglid, Cyphoderris strepitans,entails the generation of sound signals and the provision of nuptial gifts to mates. These food gifts take two forms: (1) a gelatinous mass (spermatophylax) augmenting the spermatophore and (2) fleshy metathoracic wings adapted to be eaten. The female consumes a portion of the male's underwings during courtship and copulation and the spermatophylax afterward. The incidence of wing-feeding wounds can be used to monitor the mating success of field-caught males. If, when a male mates, he compromises his ability to provide subsequent nutritive gifts, females would benefit by mating with virgin rather than nonvirgin males. To test this, mating success of virgin and nonvirgin males was compared in a field population. Virgins were found to obtain more matings than explained by their numbers relative to nonvirgins in the population. We conclude that, having mated, a male is at a disadvantage, relative to his virgin competitors, in securing further matings.
    Type of Medium: Electronic Resource
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