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  • 4-chloro-5-sulfamoylanthranilic acid  (1)
  • Actin filaments  (1)
  • Springer  (2)
  • American Association for the Advancement of Science (AAAS)
  • American Chemical Society
  • 1985-1989  (2)
Collection
Publisher
  • Springer  (2)
  • American Association for the Advancement of Science (AAAS)
  • American Chemical Society
Years
  • 1985-1989  (2)
Year
  • 1
    ISSN: 1432-1041
    Keywords: frusemide ; kidney transplants ; metabolism ; renal function ; glucuronidated frusemide ; 4-chloro-5-sulfamoylanthranilic acid
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology , Medicine
    Notes: Summary Urine from 5 renal transplant recipients treated with frusemide was analyzed for unchanged frusemide (F), glucuronidated frusemide (G) and 4-chloro-5-sulfamoylanthranilic acid (CSA) by HPLC. In 3 recipients, whose renal function recovered steadily and whose hepatic function was normal throughout, the ratio of frusemide to its metabolites, F/(F+G+CSA), increased steadily in conjunction with the recovery of renal function. In one patient, who received frusemide 200–400 mg/day i.v., the urinary CSA concentration was 64–102 µg·ml−1. In 2 patients who experienced shock and/or hepatic dysfunction after transplantation, the F/(F+G+CSA) ratio fluctuated.
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Springer
    Cell & tissue research 258 (1989), S. 373-380 
    ISSN: 1432-0878
    Keywords: Stress fibers ; Mesothelium ; Fluorescent cytochemistry ; Actin filaments ; Cytoskeleton ; Rana catesbeiana (Anura)
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary Actin-containing cytoplasmic fibers in mesothelial cells of the abdominal wall of the bullfrog, Rana catesbeiana, were visualized by rhodamine-phalloidin staining of en face preparations of mesothelial cells. These fibers ran straight and were aligned parallel with each other. They also showed immunofluorescence staining with antibody against myosin or α-actinin. Electron microscopy revealed the presence of microfilament bundles in the basal cytoplasm of the cells. These cytoplasmic fibers may be comparable to the stress fibers observed in cultured cells. The mesothelial cells of tadpoles initially developed stress fibers when they underwent transformation from a polygonal to a spindle-like shape. Such fibers were also present in the polygonal cells of frogs. Expression of stress fibers in these cells seems to correspond to the expansion of the abdominal wall caused by marked growth of some intraperitoneal organs. The stress fibers in the mesothelial cells may serve to regulate cellular transformation and, further, may play a role in maintaining cellular or epithelial integrity by strengthening the cellular attachment to subepithelial tissue against probable tension load on the abdominal wall.
    Type of Medium: Electronic Resource
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