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  • Chemistry  (3,829)
  • Analytical Chemistry and Spectroscopy  (752)
  • LUNAR AND PLANETARY EXPLORATION  (446)
  • Aerodynamics
  • 1985-1989  (3,904)
  • 1935-1939  (375)
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Keywords
Publisher
Years
Year
  • 1
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    The site of attachment in human rhinovirus 14 for antiviral agents that inhibit uncoating (1986)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1986-09-19
    Description: WIN 51711 and WIN 52084 are structurally related, antiviral compounds that inhibit the replication of rhino (common cold) viruses and related picornaviruses. They prevent the pH-mediated uncoating of the viral RNA. The compounds consist of a 3-methylisoxazole group that inserts itself into the hydrophobic interior of the VP1 beta-barrel, a connecting seven-membered aliphatic chain, and a 4-oxazolinylphenoxy group (OP) that covers the entrance to an ion channel in the floor of the "canyon." Viral disassembly may be inhibited by preventing the collapse of the VP1 hydrophobic pocket or by blocking the flow of ions into the virus interior.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Smith, T J -- Kremer, M J -- Luo, M -- Vriend, G -- Arnold, E -- Kamer, G -- Rossmann, M G -- McKinlay, M A -- Diana, G D -- Otto, M J -- New York, N.Y. -- Science. 1986 Sep 19;233(4770):1286-93.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/3018924" target="_blank"〉PubMed〈/a〉
    Keywords: Antiviral Agents/metabolism/*pharmacology ; Binding Sites ; Chemical Phenomena ; Chemistry ; Humans ; Isoxazoles/metabolism/pharmacology ; Poliovirus/drug effects/metabolism ; Rhinovirus/*drug effects/metabolism ; X-Ray Diffraction
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
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    PAPER CURRENT
  • 2
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    Voyager radio science observations of Neptune and Triton (1989)
    In:  Other Sources
    Details
    Publication Date: 2011-08-19
    Description: Voyager 2 undertook radio science investigations of the Neptune and Triton masses and densities, as well as of their atmospheric and ionospheric vertical structures, the atmospheric composition and low-order gravitational harmonics of Neptune, and ring material characteristics. Upon probing the atmosphere of Neptune to a pressure level of about 500,000 Pa, the effects of a methane cloud region and of ammonia absorption below the cloud have become apparent. The tenuous neutral atmosphere of Triton produced distinct signatures in the occultation data; it is inferred that the Triton atmosphere is controlled by water-pressure equilibrium with surface ices.
    Keywords: LUNAR AND PLANETARY EXPLORATION
    Type: Science (ISSN 0036-8075); 246; 1466-147
    Format: text
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    NASA TECHNICAL REPORTS
  • 3
    Electronic Resource
    Electronic Resource
    The development of molecular orientation and morphological texture in thermotropic copolyesters (1985)
    Stamford, Conn. [u.a.] : Wiley-Blackwell
    Polymer Engineering and Science 25 (1985), S. 888-895 
    Details
    ISSN: 0032-3888
    Keywords: Chemistry ; Chemical Engineering
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology , Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics , Physics
    Notes: Liquid crystalline polymers can be processed to form high strength/modulus materials. In processing these materials, it is apparent that molecular orientation is an important factor in determining the physical strength of the processed materials. In this study a systematic investigation was carried out to determine how a thermotropic copolyester of parahydroxybenzoic acid (PHB) and polyethylene terephthalate (PET) responds to two basic types of flows: shear and extensional flow. This was accomplished by preparing sheared and extended samples under controlled conditions of temperature and flow history. Sheared disks were prepared using a disk and plate geometry of a Rheometrics Mechanical Spectrometer (RMS model 605), while extended ribbons were prepared using a slit die attached to an Instron capillary rheometer. Two copolymerer compositions of 60 mole percent and 80 mol percent PHB were investigated. The sheared disks and extended ribbons were investigated for molecular orientation and morphological textures using wide angle x-ray scattering (WAXS) and scanning electron microscopy (SEM) analysis, respectively. It was found that extensional flow has a greater capacity for orienting such materials than shear flow. Samples annealed at their softening points for 1 minute (240°C for the 60 mole percent PHB/PET copolymer and 300°C for the 80 mole percent PHB/PET copolymer) showed no significant loss of orientation, indicating that once orientation is produced it may remain in the melt for a long period of time. Sheared samples prepared by shearing the sample while cooling showed significantly higher degrees of orientation than those not cooled while being sheared. This may indicate that a minimum stress level exists for the production of orientation in shear flow.
    Additional Material: 16 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/pen.760251405
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    Paper (German National Licenses)
    Fulltext
  • 4
    Electronic Resource
    Electronic Resource
    A SIMS calibration exercise using multi-element (Cr, Fe and Zn) implanted GaAs (1987)
    Chichester [u.a.] : Wiley-Blackwell
    Surface and Interface Analysis 10 (1987), S. 338-342 
    Details
    ISSN: 0142-2421
    Keywords: Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Physics
    Notes: Multi-element (52Cr, 56Fe and 66Zn) implanted GaAs samples have been prepared specially for SIMS calibration. Absolute chemical measurements gave retained ion doses which agreed to within 12% of the nominal implanted dose (2.0 × 1014 atoms cm-2). Comparative SIMS depth profiles with five instruments gave Cr mode depth data which showed a variability of 5%. After data normalization to a common mode depth (168 nm) the shape of all profiles showed good agreement. SIMS anàlysis of similar samples containing lower dose implants (1.0 × 1013 atoms cm-2) showed that ∼50% of the Cr was contained in the near surface region (0-0.03 μm). This surface peak was not observed in profiles of samples which had been singly implanted with Cr. It is proposed that the Cr surface peak results from radiation enhanced out-diffusion initiated by the subsequent Fe implant. Whilst the high dose multi-implant samples showed a similar Cr surface accumulation, its magnitude in relation to the ion implanted dose, was smaller. These samples therefore form reliable calibration specimens for the simultaneous determination of the secondary ion responses of Cr, Fe and Zn in GaAs.
    Additional Material: 4 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/sia.740100705
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  • 5
    Electronic Resource
    Electronic Resource
    Letters to the editor (1985)
    Chichester : Wiley-Blackwell
    Biological Mass Spectrometry 20 (1985), S. 422-431 
    Details
    ISSN: 0030-493X
    Keywords: Chemistry ; Analytical Chemistry and Spectroscopy
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Additional Material: 6 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/oms.1210200608
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  • 6
    Electronic Resource
    Electronic Resource
    Human bone cell cultures: A new model for studying the mechanism of action of calcitonin (1985)
    New York, NY [u.a.] : Wiley-Blackwell
    Cell Biochemistry and Function 3 (1985), S. 179-184 
    Details
    ISSN: 0263-6484
    Keywords: Human bone cell cultures ; calcitonin action ; 45Ca incorporation ; cyclic nucleotides ; Chemistry ; Biochemistry and Biotechnology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Medicine
    Notes: An investigation on cell cultures obtained from temporal human bone fragments showed that they provide a suitable model for studying the mechanism involved in calcitonin action on bone cells. Furthermore they demonstrated: (1) a transitory increase in 45Ca uptake that returned to control values ten minutes after the hormone was added; (2) a relation between 45Ca uptake and increased cAMP concentrations when these were measured at the same time intervals; (3) a reproduction of the salmon calcitonin (sCT) effect after incubation of the cultures with either db-cAMP or db-cGMP and (4) inhibition of 45Ca uptake and parallel decrease in cAMP levels with propanol.These results suggest that in human bone cell cultures, sCT acts as a temporary promoter of 45Ca uptake, probably by activating an adenylate-cyclase system through a β-receptor.
    Additional Material: 4 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/cbf.290030304
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  • 7
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    Voyager 2 radio science observations of the Uranian system Atmosphere, rings, and satellites (1986)
    In:  Other Sources
    Details
    Publication Date: 2011-08-19
    Description: The results of preliminary analyses of radio occultation data obtained by Voyager 2 as it passed Uranus are described. The occultations took place between 2-7 deg S latitude and yielded atmospheric temperature profiles between pressure levels of 10-900 mbar, an altitude range of 100 km. The mole fractions of hydrogen and helium in the tropopause were estimated, in conjunction with IR data, to about 0.85 and 0.10-0.20, respectively. Radio signal intensity data indicated the presence of a cloud deck of CH4 ice at a pressure level of 1300 mbar and a temperature of 81 K, implying a CH4 mole fraction of 0.02 at very low altitudes. The ionosphere extended upward, in two levels, to more than 10,000 km altitude. The ring system was different than the one around Saturn and possessed cylindrical substructures. The radio data also permitted mass density estimates for the five major moons, i.e., about 1.40 gr/cu cm, a value which rules out cometary origins.
    Keywords: LUNAR AND PLANETARY EXPLORATION
    Type: Science (ISSN 0036-8075); 233; 79-84
    Format: text
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    NASA TECHNICAL REPORTS
  • 8
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    Mapping and Geological Analysis of Mercury and Venus Radar Ranging Data (1985)
    In:  CASI
    Details
    Publication Date: 2014-10-09
    Description: Although many radar profiles and images of the areas within 20 deg of Mercury's equator had been obtained from 1971, at both Goldstone and Arecibo radar facilities, surprisingly little geological analysis had been done with these data until recently. Topographic profiles and radar roughness reflectivity images which can be derived from these data will be crucial in completing the geological mapping of Mercury now underway at the U.S. Geological Survey. Earth based radar observations of Mercury and the other terrestrial planets as well are a potentially very valuable tool in the determination of the physical nature of their surfaces. Processing of available radar data must be completed to establish any systematic relationship between raar reflectivities and roughness, density, dielectric constant, and other related geological parameters.
    Keywords: LUNAR AND PLANETARY EXPLORATION
    Type: NASA, Washington Repts. of Planetary Geol. and Geophys. Program, 1984; p 453-455
    Format: text
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    NASA TECHNICAL REPORTS
  • 9
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    Chemical analysis of aerosol in the Venusian cloud layer by reaction gas chromatography on board the Vega landers (1986)
    In:  CASI
    Details
    Publication Date: 2019-08-13
    Description: The experiment on sulfuric acid aerosol determination in the Venusian cloud layer on board the Vega landers is described. An average content of sulfuric acid of approximately 1 mg/cu m was found for the samples taken from the atmosphere at heights from 63 to 48 km and analyzed with the SIGMA-3 chromatograph. Sulfur dioxide (SO2) was revealed in the gaseous sample at the height of 48 km. From the experimental results and blank run measurements, a suggestion is made that the Venusian cloud layer aerosol consists of more complicated particles than the sulfuric acid water solution does.
    Keywords: LUNAR AND PLANETARY EXPLORATION
    Type: NASA-TM-88421 , NAS 1.15:88421
    Format: application/pdf
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    NASA TECHNICAL REPORTS
  • 10
    Electronic Resource
    Electronic Resource
    Star-like polymer conjugates of biologically active polypeptides (1985)
    New York : Wiley-Blackwell
    Die Makromolekulare Chemie 9 (1985), S. 239-249 
    Details
    ISSN: 0025-116X
    Keywords: Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology , Physics
    Notes: A general approach to the preparation of star-like carbon chain polymeric conjugates with proteins has been suggested. The influence of the modification on the spatial structure, biological activity, immunoreactivity and enzyme degradation of the protein (insulin) is discussed.
    Additional Material: 6 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/macp.1985.020091985135
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