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  • Animals  (2)
  • Polymer and Materials Science  (2)
  • *Genes, Regulator  (1)
  • 1985-1989  (5)
  • 1940-1944
  • 1
    Electronic Resource
    Electronic Resource
    Weinheim : Wiley-Blackwell
    Electroanalysis 1 (1989), S. 1-11 
    ISSN: 1040-0397
    Keywords: Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Notes: A review of the various simultaneous ESR-electrochemical techniques that have been developed is presented. Special advantages and disadvantages of the stationary and flow-through cell configurations are described. A critical evaluation of the in situ ESR-electrochemical cells developed to date has also been made. A selected survey of applications is presented to illustrate the wide range of chemical information on redox reactions which can be obtained by the simultaneous ESR-electrochemical method.
    Additional Material: 4 Ill.
    Type of Medium: Electronic Resource
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  • 2
    ISSN: 1040-0397
    Keywords: Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Notes: Gold and platinum ultrathin ring microelectrodes (0.1-0.5 mm thick, 1.5-4 mm diameter) were made by sputtering, from fired metalloorganic paint, and from foil for use as sensors in a thick-layer wall-jet flow cell. An end-on array of three 0.1 μm × 0.5 mm gold band electrodes were mounted parallel to the flow direction in a thin-layer channel cell. These ultrathin sensors, along with a jet-centered carbon microdisk, were evaluated in the amperometric flow-injection mode for temporal stability, calibration sensitivity, detectivity, background signal, and flow rate dependence of the analytical signal using ferrocene samples in acetonitrile containing 10-4-10-2 M TEAP. The detectivity of gold paint ring electrodes made on borosilicate glass was 3-6 nM, an order of magnitude lower than any of the other electrodes tested. Analytical signals from gold paint and foil rings and the carbon microdisk had the best temporal stability. The current for the ultrathin band array in a channel cell was flow rate-independent, and the exponential dependence of cell current on flow rate was 0.11-0.14 for ultrathin rings in the thick-layer wall-jet mode.
    Additional Material: 9 Ill.
    Type of Medium: Electronic Resource
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  • 3
    Publication Date: 1986-02-21
    Description: Partial amino acid sequence analysis of a purified lymphocyte homing receptor demonstrates the presence of two amino termini, one of which corresponds precisely to the amino terminus of ubiquitin. This observation extends the province of this conserved polypeptide to the cell surface and leads to a proposed model of the receptor complex as a core polypeptide modified by glycosylation and ubiquitination. Independent antibodies to ubiquitin serve to identify additional cell surface species, an indication that ubiquitination of cell surface proteins may be more general. It is proposed that functional binding of lymphocytes to lymph node high endothelial venules might involve the ubiquitinated region of the receptor; if true, cell surface ubiquitin could play a more general role in cell-cell interaction and adhesion.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Siegelman, M -- Bond, M W -- Gallatin, W M -- St John, T -- Smith, H T -- Fried, V A -- Weissman, I L -- AI 19512/AI/NIAID NIH HHS/ -- CA 09151/CA/NCI NIH HHS/ -- GM 31461/GM/NIGMS NIH HHS/ -- New York, N.Y. -- Science. 1986 Feb 21;231(4740):823-9.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/3003913" target="_blank"〉PubMed〈/a〉
    Keywords: Amino Acid Sequence ; Animals ; Antibodies, Monoclonal ; Cell Movement ; Endothelium/metabolism ; Glycoproteins/metabolism/*physiology ; Glycoside Hydrolases/metabolism ; High Mobility Group Proteins/*metabolism ; Lymphocytes/*physiology ; Mannosyl-Glycoprotein Endo-beta-N-Acetylglucosaminidase ; Membrane Proteins/metabolism/*physiology ; Mice ; Molecular Weight ; Protein Processing, Post-Translational ; Receptors, Cell Surface/metabolism/*physiology ; Ubiquitins/immunology/*metabolism
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 4
    Publication Date: 1987-03-20
    Description: The thymidine kinase (tk) promoter of herpes simplex virus includes an octanucleotide sequence motif (ATTTGCAT) that is also an essential component of immunoglobulin kappa gene promoters. In the absence of an enhancer, tk promoter derivatives that contain this element support a higher rate of transcription than those that lack it. The action of the kappa enhancer augments that of the octanucleotide in B lymphoid cells; when both elements are present, tk promoter activity is increased by more than an order of magnitude. In contrast, the presence of the octanucleotide in this promoter markedly reduces its response to a nonimmunoglobulin enhancer. These results suggest that the octanucleotide may mediate a selective interaction among promoters and enhancers.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Parslow, T G -- Jones, S D -- Bond, B -- Yamamoto, K R -- AI22536/AI/NIAID NIH HHS/ -- CA20535/CA/NCI NIH HHS/ -- CM07810/CM/NCI NIH HHS/ -- New York, N.Y. -- Science. 1987 Mar 20;235(4795):1498-501.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/3029871" target="_blank"〉PubMed〈/a〉
    Keywords: DNA, Viral/genetics ; *Enhancer Elements, Genetic ; *Gene Expression Regulation ; *Genes, Regulator ; Immunoglobulin kappa-Chains/*genetics ; Lymphocytes/physiology ; Moloney murine sarcoma virus/genetics ; *Promoter Regions, Genetic ; Simplexvirus/genetics ; Thymidine Kinase/genetics
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 5
    Publication Date: 1987-03-20
    Description: This report describes the characterization of a genomic locus in the rat that encodes overlapping genes occupying both strands of the same piece of DNA. One gene (strand) encodes gonadotropin-releasing hormone (GnRH). A second gene, SH, is transcribed from the other DNA strand to produce RNA of undefined function. The RNAs transcribed from each DNA strand are spliced and polyadenylated, and share significant exon domains. GnRH is expressed in the central nervous system while SH transcripts are present in the heart. Thus, the genome of a mammalian organism encodes two distinct genes by using both strands of the same DNA.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Adelman, J P -- Bond, C T -- Douglass, J -- Herbert, E -- AM-16879/AM/NIADDK NIH HHS/ -- AM-30155/AM/NIADDK NIH HHS/ -- DA-02736/DA/NIDA NIH HHS/ -- New York, N.Y. -- Science. 1987 Mar 20;235(4795):1514-7.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/3547652" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Base Sequence ; DNA/*genetics ; Exons ; *Genes ; Gonadotropin-Releasing Hormone/*genetics ; Heart/physiology ; Hypothalamus/physiology ; Introns ; RNA Splicing ; RNA, Messenger/*genetics ; Rats ; Templates, Genetic ; Transcription, Genetic
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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