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  • CO2 response  (1)
  • Child development disorders  (1)
  • 1985-1989  (2)
  • 1950-1954
  • 1930-1934
Collection
Keywords
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  • 1985-1989  (2)
  • 1950-1954
  • 1930-1934
Year
  • 1
    Electronic Resource
    Electronic Resource
    The effects on ventilation of ketorolac in comparison with morphine (1988)
    Springer
    European journal of clinical pharmacology 35 (1988), S. 491-494 
    Details
    ISSN: 1432-1041
    Keywords: ketorolac ; morphine ; ventilation ; CO2 response
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology , Medicine
    Notes: Summary We have compared the effect on ventilation of ketorolac, an injectable non-steroidal analgesic, with that of morphine in a randomized, double-blind, cross-over study, using two doses of ketorolac (10 and 90 mg i.m.) and one of morphine (10 mg i.m.). The effect on ventilation was measured with a CO2 rebreathing technique. As a measure of the effect we studied the increase in PETCO2 (CO2 shift) that caused a respiratory minute volume (RMV) equal to the RMV in the control period at 8 kPa PETCO2. Ketorolac caused insignificant CO2 shifts of about 0.10 kPa, while morphine caused a significant CO2 shift of 0.86 kPa. We conclude that ketorolac in analgesic and supra-analgesic doses has no effect on the ventilatory response to CO2 under circumstances in which significant effects are seen with morphine.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00558243
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  • 2
    Electronic Resource
    Electronic Resource
    Correlation of echoencephalographic findings and neurodevelopmental outcome: Intracranial hemorrhage and ventriculomegaly in infants of birth weight 1,000 grams or less (1987)
    Springer
    Journal of clinical monitoring and computing 3 (1987), S. 178-186 
    Details
    ISSN: 1573-2614
    Keywords: Measurement techniques: echoencephalography ; Hemorrhage ; cerebral ; Brain: hemorrhage ; hydrocephalus ; Complications: neurologic ; Child development disorders ; Infant ; premature: diseases
    Source: Springer Online Journal Archives 1860-2000
    Topics: Computer Science , Medicine
    Notes: Abstract Echoencephalograms were obtained for 118 of 121 successive infants who were admitted to the Stanford intensive care nursery, weighed 1,000 g or less at birth, and survived long enough for at least one study to be performed. Eightyeight of these infants survived and were followed up for 1 to 3 years; psychometric testing (Bayley Scales of Infant Development, Stanford-Binet Intelligence Scale, or both) was performed on 81% of these infants. Subependymal-intraventricular hemorrhages or intraparenchymal hemorrhages were associated with impaired development, but ventriculomegaly was not. The absence of echoencephalographic abnormalities did not exclude the possibility of impaired development in many infants. Periventricular leukomalacia was not observed. These data support independent scoring of subependymal intraventricular hemorrhages, intraparenchymal hemorrhages, and ventriculomegaly, rather than use of combined scales for prognostic purposes.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01695940
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