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  • Cell & Developmental Biology  (608)
  • AERODYNAMICS  (569)
  • Chemical Engineering  (552)
  • FLUID MECHANICS AND HEAT TRANSFER  (326)
  • Aircraft Design, Testing and Performance
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  • 1985-1989  (1,938)
  • 1955-1959  (194)
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  • 1
    Publication Date: 2013-08-31
    Description: A brief overview of flow separation phenomena is provided. Langley has many active research programs in flow separation related areas. Three cases are presented which describe specific examples of flow separation research. In each example, a description of the fundamental fluid physics and the complexity of the flow field is presented along with a method of either reducing or controlling the extent of separation. The following examples are discussed: flow over a smooth surface with an adverse pressure gradient; flow over a surface with a geometric discontinuity; and flow with shock-boundary layer interactions. These results will show that improvements are being made in the understanding of flow separation and its control.
    Keywords: FLUID MECHANICS AND HEAT TRANSFER
    Type: Langley Symposium on Aerodynamics, Volume 1; p 361-374
    Format: application/pdf
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  • 2
    ISSN: 0730-2312
    Keywords: tumor metastasis ; gene expression ; oncogenes ; virus antigens ; glycoproteins ; Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Chemistry and Pharmacology , Medicine
    Notes: A metastatic variant cell subline of the Abelson virus-transformed murine large lymphoma/lymphosarcoma RAW 117 has been selected in vivo ten times for liver colonization. Highly metastatic subline RAW117-H10 forms greater than 200 times as many gross surface liver tumor nodules as the parental line RAW117-P. Analysis of cellular proteins and glycoproteins indicates reduced expression of murine Moloney leukemia virus-associated p15, p30, and gp70, and increased expression of a sialoglycoprotein, gp150, in the highly metastatic H10 cells. Northern analyses of oncogene expression suggested that mRNA of various oncogenes was expressed equally or not expressed in the RAW117 cells of differing metastatic potential. Differential gene expression was examined using a cDNA library of 17,600 clones established from poly A+ mRNA isolated from H10 cells. The cDNA library was screened by the colony hybridization technique using probes made from both RAW117-P and -H10 cells. Approximately 99.5% of these cDNA clones were expressed identically in P and H10 cells. Of the few differentially expressed cDNA clones (approx. 150/17,600), one-half of these were identified as Moloney leukemia virus sequences in a separate probing with a radiolabeled Moloney leukemia virus probe. The remainder of the differentially expressed mRNA detected by colony hybridization of the cDNA library were expressed at higher levels (approx. 1/6) or lower levels (approx. 1/3) in the highly metastatic H10 cells.
    Additional Material: 3 Ill.
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    Stamford, Conn. [u.a.] : Wiley-Blackwell
    Polymer Engineering and Science 29 (1989), S. 1215-1218 
    ISSN: 0032-3888
    Keywords: Chemistry ; Chemical Engineering
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology , Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics , Physics
    Notes: Transparent dimethyl siloxane network polymers with refractive indices near 1.40 may be applied to fused silica fibers (n = 1.458) as they are drawn to produce plastic-clad silica (PCS) optical fibers. The evanescent tail of the light energy propagating in the core of such fibers extends into the silicone cladding, where it interacts with chemical species present in the polymer. If the silicone is doped with a dye, the absorption spectrum or fluorescence spectrum of the dye is reflected in the transmission spectrum of the fiber. Further, if the dye changes its absorption spectrum or fluorescence spectrum as a result of diffusion of a chemical species into the silicone, the change is detectable in the fiber output. The polymer material properties which determine the performance of these sensors are described, along with examples of sensors for ammonia and oxygen which utilize either color changing or fluorescent dyes.
    Additional Material: 8 Ill.
    Type of Medium: Electronic Resource
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  • 4
    ISSN: 0148-7280
    Keywords: heparin ; fertilization ; dextran sulfate ; fucose sulfate glycoconjugate ; Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology
    Notes: The effects of sulfated glycoconjugates on the preparation of mammalian sperm for fertilization were investigated. The three sulfated glycoconjugates tested were heparin, dextran sulfate, and the fucose sulfate glycoconjugate (FSG) from the sea urchin egg jelly coat. In vivo, FSG induces the acrosome reaction in sea urchin sperm. Bovine sperm were found to be capacitated by heparin and FSG as judged both by ability of lysophosphatidylcholine (LC) to induce an acrosome reaction and by ability to fertilize bovine oocytes in vitro. The mechanism by which heparin or FSG capacitated bovine sperm appeared similar, since glucose inhibited capacitation by both glycoconjugates. In contrast to effects on bovine sperm, heparin and FSG induced the acrosome reaction in capacitated hamster sperm. When hamster sperm were incubated under noncapacitating conditions, heparin had no effect on capacitation or the acrosome reaction. Three molecular weights (MW) of dextran sulfate (5,000, 8,000, 500,000) were found to capacitate bovine sperm as judged by the ability of LC to induce an acrosome reaction. Whereas bovine sperm incubated with 5,000 or 8,000 M W dextran sulfate fertilized more bovine oocytes than control sperm (P 〈0.05), sperm treated with 500,000 M W dextran sulfate failed to penetrate oocytes. The high-MW dextran sulfate appeared to interact with the zona pellucida and/or sperm to prevent sperm binding. Results suggest that sulfated glycoconjugates may prepare sperm for fertilization across a wide range of species.
    Additional Material: 5 Ill.
    Type of Medium: Electronic Resource
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  • 5
    Electronic Resource
    Electronic Resource
    Brookfield, Conn. : Wiley-Blackwell
    Polymer Composites 9 (1988), S. 139-143 
    ISSN: 0272-8397
    Keywords: Chemistry ; Chemical Engineering
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Notes: The effect of filler content and applied electrical field on the electrical resistivity of poly(methyl methacrylate) (PMMA) filled with aluminum particles was investigated. The resistivity of such composite suddenly decreases by several orders of magnitude at a critical volume concentration φc. In addition, for filler contents lower than φc, the PMMA/Al composite undergoes a transition from a high to a low resistance material in correspondence of a critical value of the external applied electrical field. This value has been related to thermal breakdown occurring in the regions between conductive particles. Moreover, the permittivity spectrum as a function of frequency is reported for composites of several filler contents, and the Lal and Parshad law was used to correlate the experimental data.
    Additional Material: 8 Ill.
    Type of Medium: Electronic Resource
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  • 6
    Publication Date: 2019-06-28
    Description: A titanium multiwall/reusable surface insulation (MW/RSI) TPS concept designed to prevent local erosion of the RSI tiles on the upper surface of the Space Shuttle Orbiter body flap was investigated. The concept, which consisted of a combination of a titanium multiwall tile and an RSI tile, was evaluated by thermal analysis and structural and thermal testing of one configuration to assess the attachment scheme and thermal behavior. Results indicate that the MW/RSI concept will remain attached to the vehicle and provide the required thermal protection.
    Keywords: FLUID MECHANICS AND HEAT TRANSFER
    Type: NASA-TM-87589 , NAS 1.15:87589
    Format: application/pdf
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  • 7
    Publication Date: 2019-06-28
    Description: An investigation has been conducted in the Langley 16 Foot Transonic Tunnel to determine the weight flow measurement characteristics of a multiple critical Venturi system and the nozzle discharge coefficient characteristics of a series of convergent calibration nozzles. The effects on model discharge coefficient of nozzle throat area, model choke plate open area, nozzle pressure ratio, jet total temperature, and number and combination of operating Venturis were investigated. Tests were conducted at static conditions (tunnel wind off) at nozzle pressure ratios from 1.3 to 7.0.
    Keywords: AERODYNAMICS
    Type: NASA-TM-86405 , L-15960 , NAS 1.15:86405
    Format: application/pdf
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  • 8
    Publication Date: 2019-06-28
    Description: Attention is given to a new approach to solving full potential equations about arbitrary configurations. Numerical algorithms from such fields as finite elements, preconditioned Krylov subspace methods, discrete Fourier analysis, and integral equations are combined to take advantage of the size and speed of current and emerging supercomputers. On the basis of this appraoch, a robust, efficient and easy to use computer code referred to as TRANAIR has been developed for transonic analysis of complex geometries.
    Keywords: AERODYNAMICS
    Type: AIAA PAPER 87-0034
    Format: text
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  • 9
    Publication Date: 2019-06-28
    Description: A numerical model based on a transformed, conservative form of the three dimensional Navier-Stokes equation and an analytical model based on lumped fluid parameters are presented and compared with studies of modeled rotor bearing seal systems. The rotor destabilizing factors are related to the rotative character of the flow field. It is shown that these destabilizing factors can be reduced through a decrease in the fluid average circumferential velocity. However, the rotative character of the flow field is a complex three dimensional system with bifurcated secondary flow patterns that significantly alter the fluid circumferential velocity. By transforming the Navier-Stokes equations to those for a rotating observer and using the numerical code PHOENICS-84 with a nonorthogonal body fitted grid, several numerical experiments were carried out to demonstrate the character of this complex flow field. In general, fluid injection and/or preswirl of the flow field opposing the shaft rotation significantly intensified these secondary recirculation zones and thus reduced the average circumferential velocity; injection or preswirl in the direction of rotation significantly weakened these zones.
    Keywords: FLUID MECHANICS AND HEAT TRANSFER
    Type: NASA-TM-100268 , E-3903 , NAS 1.15:100268
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  • 10
    Publication Date: 2019-06-28
    Description: An upwind-biased implicit approximate factorization Navier-Stokes algorithm is applied to a variety of steady transonic airfoil cases, using the NACA 0012, RAE 2822, and Jones supercritical airfoils. The thin-layer form of the compressible Navier-Stokes equations is used. Both the CYBER 205 and CRAY 2 supercomputers are utilized, with average computational speeds of about 18 and 16 microsec/gridpoint/iteration, respectively. Lift curves, drag polars, and variations in drag coefficient with Mach number are determined for the NACA 0012 and Jones supercritical airfoils. Also, several cases are computed for comparison with experiment. The effect of grid density and grid extent on a typical turbulent airfoil solution is shown. An algebraic eddy-viscosity turbulence model is used for all of the computations.
    Keywords: AERODYNAMICS
    Type: AIAA PAPER 87-0413
    Format: text
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