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  • Polymer and Materials Science  (2)
  • concentration-effect relationship  (1)
  • 1985-1989  (3)
  • 1970-1974
  • 1
    Electronic Resource
    Electronic Resource
    Springer
    European journal of clinical pharmacology 34 (1988), S. 55-59 
    ISSN: 1432-1041
    Keywords: doxapram ; ventilatory function ; occlusion pressure ; serum drug concentration ; concentration-effect relationship
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology , Medicine
    Notes: Summary To investigate the means by which doxapram affects the control of ventilation, ventilatory function and P0.1 have been related to serum doxapram concentration during a 45-min infusion of doxapram hydrochloride in 7 healthy, conscious subjects under normoxic conditions. Serum doxapram concentrations increased during the infusion: 1.88, 2.48, 3.42, and 3.97 µg/ml after 5, 10, 30 and 45 min, respectively. The majority of significant changes in the measurements from the baseline were observed at 30 and 45 min: $${{\dot V}}_{{E}}$$ , VT, P0.1, P0.1/end-tidal CO2 tension, VT/Ti and blood pressure were increased, and end-tidal CO2 tension was decreased. No significant changes in Pdimax, Ti/Ttot, $${{\dot V}}_{{E}}$$ /P0.1, and P0.1/(VT/Ti) were observed. A correlation was observed between the % increases in P0.1 and $${{\dot V}}_{{E}}$$ and doxapram concentration, and between $${{\dot V}}_{{E}}$$ and P0.1. The doxapram-induced increase in $${{\dot V}}_{{E}}$$ appears to be caused by increased neural drive. It is related to the serum drug concentration in the conscious subject.
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    New York, NY [u.a.] : Wiley-Blackwell
    Journal of Applied Polymer Science 34 (1987), S. 1429-1437 
    ISSN: 0021-8995
    Keywords: Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology , Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics , Physics
    Notes: A new thermal conduction model is proposed for a polymer system filled with a mixture of several types of particles. Predicted values by the new model are compared with experimental data. The model is derived by extending a model that was previously proposed for a two-phase system. The following equation is derived from the new model: log λ = V · (X2 · C2 · log λ2 + X3 · C3 · log λ3 + (1 - V) log (C1 · λ1. When the thermal conductivities of polymer and particles (λ1, λ2, λ3, …) and a mixing ratio of particles (X2, X3, …) are known, thermal conductivity of the filled polymer (λ) with several types of particles can be estimated from the equation, with any volume content of particles (V). Furthermore, from each polymer-filler composite (two-phase system) data, the thermal conductivity of a composite filled with different filler particles can be estimated.
    Additional Material: 6 Ill.
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    Bognor Regis [u.a.] : Wiley-Blackwell
    Journal of Polymer Science Part A: Polymer Chemistry 25 (1987), S. 3173-3176 
    ISSN: 0887-624X
    Keywords: Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Additional Material: 2 Ill.
    Type of Medium: Electronic Resource
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