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  • 1
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    A major human histone gene cluster on the long arm of chromosome 1 (1984)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1984-11-16
    Description: A human histone gene cluster was assigned to chromosome 1 by Southern blot analysis of DNA's from a series of mouse-human somatic cell hybrids with 32P-labeled cloned human H4 and H3 histone DNA as probes. Localization of this histone gene cluster on the long arm of chromosome 1 was confirmed by in situ hybridization of this DNA probe to metaphase chromosomes.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Green, L -- Van Antwerpen, R -- Stein, J -- Stein, G -- Tripputi, P -- Emanuel, B -- Selden, J -- Croce, C -- GM20138/GM/NIGMS NIH HHS/ -- GM20700/GM/NIGMS NIH HHS/ -- GM32010/GM/NIGMS NIH HHS/ -- New York, N.Y. -- Science. 1984 Nov 16;226(4676):838-40.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/6494913" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; *Chromosome Mapping ; *Chromosomes, Human, 1-3 ; Chromosomes, Human, 6-12 and X ; DNA/metabolism ; Genes ; Histones/*genetics ; Humans ; Hybrid Cells/metabolism ; Mice ; Nucleic Acid Hybridization
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
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  • 2
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    Clustering of human H1 and core histone genes (1984)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1984-06-08
    Description: An H1 histone gene was isolated from a 15-kilobase human DNA genomic sequence. The presence of H2A, H2B, H3, and H4 genes in this same 15-kilobase fragment indicates that mammalian core and H1 histone genes are clustered.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Carozzi, N -- Marashi, F -- Plumb, M -- Zimmerman, S -- Zimmerman, A -- Coles, L S -- Wells, J R -- Stein, G -- Stein, J -- GM 32010/GM/NIGMS NIH HHS/ -- New York, N.Y. -- Science. 1984 Jun 8;224(4653):1115-7.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/6719136" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Base Sequence ; DNA/genetics ; *Genes ; HeLa Cells ; Histones/*genetics ; Humans ; Nucleic Acid Hybridization ; Rabbits ; Trout ; Xenopus
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
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  • 3
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    Stress-induced suppression of immunity in adrenalectomized rats (1983)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1983-09-23
    Description: Stress-induced suppression of lymphocyte stimulation by phytohemagglutinin was demonstrated in Isolated lymphocytes and in cultures of whole blood from adrenalectomized rats. The results demonstrate that corticosteroid independent mechanisms participate in the suppression of lymphocyte function by stressors. Stress-induced lymphopenia, however, was found to be adrenal dependent, indicating that the modulation of immunity by stress is complex and multidetermined.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Keller, S E -- Weiss, J M -- Schleifer, S J -- Miller, N E -- Stein, M -- New York, N.Y. -- Science. 1983 Sep 23;221(4617):1301-4.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/6612346" target="_blank"〉PubMed〈/a〉
    Keywords: *Adrenalectomy ; Animals ; Corticosterone/*pharmacology ; *Immune Tolerance/drug effects ; Leukocyte Count ; *Lymphocyte Activation ; Lymphocytes/*immunology ; Rats ; Spleen/immunology ; Stress, Physiological/*immunology
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 4
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    Interactions among converging sensory inputs in the superior colliculus (1983)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1983-07-22
    Description: The responses of superior colliculus cells to a given sensory stimulus were influenced by the presence or absence of other sensory cues. By pooling sensory inputs, many superior colliculus cells seem to amplify the effects of subtle environmental cues in certain conditions, whereas in others, responses to normally effective stimuli can be blocked. The observations illustrate the dynamic, interactive nature of the multisensory inputs which characterize the deeper laminae of the superior colliculus.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Meredith, M A -- Stein, B E -- EY 04119/EY/NEI NIH HHS/ -- NS 06838/NS/NINDS NIH HHS/ -- New York, N.Y. -- Science. 1983 Jul 22;221(4608):389-91.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/6867718" target="_blank"〉PubMed〈/a〉
    Keywords: Acoustic Stimulation ; Animals ; Cats ; Cricetinae ; Neural Inhibition ; Photic Stimulation ; Sensory Thresholds ; Superior Colliculi/cytology/*physiology
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 5
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    Fetal brain transplant: reduction of cognitive deficits in rats with frontal cortex lesions (1983)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1983-07-29
    Description: Frontal cortex and cerebellar tissue from fetal rats was implanted into the damaged frontal cortex of adults. Cognitive deficits in spatial alternation learning that follow bilateral destruction of medial frontal cortex were reduced in rats with frontal cortex implants but not in those with implants of cerebellum. Histological evaluation showed that connections were made between the frontal cortex implants and host brain tissue.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Labbe, R -- Firl, A Jr -- Mufson, E J -- Stein, D G -- New York, N.Y. -- Science. 1983 Jul 29;221(4609):470-2.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/6683427" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Behavior, Animal ; Cerebellum/*transplantation ; Cerebral Cortex/injuries/*transplantation ; Cognition Disorders/*physiopathology ; Fetus/*surgery ; Humans ; Male ; Rats ; Rats, Inbred Strains
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 6
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    Suppression of immunity by stress: effect of a graded series of stressors on lymphocyte stimulation in the rat (1981)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1981-09-18
    Description: In rats a graded series of stressors produced progressively greater suppression of lymphocyte function, as measured by the number of circulating lymphocytes and by phytohemagglutinin stimulation of lymphocytes in whole blood and isolated cultures. This evidence suggests that stress suppresses immunity in proportion to the intensity of the stressor.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Keller, S E -- Weiss, J M -- Schleifer, S J -- Miller, N E -- Stein, M -- New York, N.Y. -- Science. 1981 Sep 18;213(4514):1397-400.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/6973822" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Cells, Cultured ; Electroshock ; *Immune Tolerance ; Leukocyte Count ; Lymphocyte Activation ; Phytohemagglutinins/pharmacology ; Rats ; Stress, Physiological/*immunology ; T-Lymphocytes/immunology
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 7
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    An about 50,000-dalton protein in adrenal medulla: a common precursor of [Met]- and [Leu]enkephalin (1980)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1980-06-27
    Description: A protein that may be an enkephalin precursor has been identified in extracts of bovine adrenal medulla. This protein (about 50,000 daltons) appears to contain seven copies of [Met]enkephalin and one copy of [Leu]enkephalin. Digestion with trypsin and carboxypeptidase B yields [Met]enkephalin and [Leu]enkephalin in a ratio of almost 7 to 1. The enkephalins were identified by chromatography and by their binding to opiate receptors. Some characteristics of several other adrenal peptides that may serve as intermediates in the biosynthesis of the enkephalins are presented.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Lewis, R V -- Stern, A S -- Kimura, S -- Rossier, J -- Stein, S -- Udenfriend, S -- New York, N.Y. -- Science. 1980 Jun 27;208(4451):1459-61.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/7384787" target="_blank"〉PubMed〈/a〉
    Keywords: Adrenal Medulla/*analysis ; Animals ; Cattle ; Chromaffin Granules/*analysis ; Chromaffin System/*analysis ; Endorphins/*biosynthesis ; Enkephalin, Leucine ; Enkephalin, Methionine ; Enkephalins/*biosynthesis ; Molecular Weight ; Oligopeptides/analysis ; Peptide Fragments/analysis ; Protein Precursors/*analysis ; Proteins/*analysis ; Trypsin
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 8
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    Superior colliculus: control of eye movements in neonatal kittens (1980)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1980-10-03
    Description: Activation of the neonatal cat superior colliculus can produce organized eye movements before visual stimuli are capable of activating visual neurons in the colliculus. These findings are consistent with the hypothesis that eye movement development precedes, and is necessary for, visuomotor integration.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Stein, B E -- Clamann, H P -- Goldberg, S J -- EY 01442/EY/NEI NIH HHS/ -- MS 11677/PHS HHS/ -- NS/MH 15912/NS/NINDS NIH HHS/ -- New York, N.Y. -- Science. 1980 Oct 3;210(4465):78-80.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/7414323" target="_blank"〉PubMed〈/a〉
    Keywords: Age Factors ; Animals ; Animals, Newborn/*physiology ; Cats ; Electric Stimulation ; Electrodes, Implanted ; *Eye Movements ; Photic Stimulation ; Superior Colliculi/*physiology
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 9
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    Regenerating fish optic nerves and a regeneration-like response in injured optic nerves of adult rabbits (1985)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1985-05-03
    Description: Regeneration of fish optic nerve (representing regenerative central nervous system) was accompanied by increased activity of regeneration-triggering factors produced by nonneuronal cells. A graft of regenerating fish optic nerve, or a "wrap-around" implant containing medium conditioned by it, induced a response associated with regeneration in injured optic nerves of adult rabbits (representing a nonregenerative central nervous system). This response was manifested by an increase of general protein synthesis and of selective polypeptides in the retinas and by the ability of the retina to sprout in culture.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Schwartz, M -- Belkin, M -- Harel, A -- Solomon, A -- Lavie, V -- Hadani, M -- Rachailovich, I -- Stein-Izsak, C -- New York, N.Y. -- Science. 1985 May 3;228(4699):600-3.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/3983646" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Electrophoresis, Polyacrylamide Gel ; Eye Proteins/isolation & purification/physiology ; Fishes ; *Nerve Regeneration ; Optic Nerve/*physiology ; Optic Nerve Injuries ; Rabbits ; Retina/physiology
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 10
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    Descending efferents from the superior colliculus relay integrated multisensory information (1985)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1985-02-08
    Description: By means of their efferent projections to motor and premotor structures, the cells in the deep superior colliculus are intimately involved in behaviors that control the orientation of the eyes, pinnae, and head. These same efferent cells receive multiple sensory inputs, thereby apparently enabling an animal to orient its receptor organs in response to a wide variety of cues. This sensory convergence also provides a system in which motor responses need not be immutably linked to individual stimuli but can vary in reaction to the multitude of stimuli present in the environment at any given moment.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Meredith, M A -- Stein, B E -- EY04119/EY/NEI NIH HHS/ -- New York, N.Y. -- Science. 1985 Feb 8;227(4687):657-9.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/3969558" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Cats ; Electric Stimulation ; Motor Activity/physiology ; Movement ; Neurons, Afferent/physiology ; Neurons, Efferent/*physiology ; Superior Colliculi/cytology/*physiology
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
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