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  • Wiley-Blackwell  (7,577)
  • Annual Reviews
  • 1985-1989  (4,465)
  • 1980-1984  (3,536)
  • 1955-1959  (670)
  • 1940-1944  (273)
Collection
Keywords
Publisher
Years
Year
  • 1
    Electronic Resource
    Electronic Resource
    ION Channels in Drosophila (1988)
    Palo Alto, Calif. : Annual Reviews
    Annual Review of Physiology 50 (1988), S. 379-394 
    Details
    ISSN: 0066-4278
    Source: Annual Reviews Electronic Back Volume Collection 1932-2001ff
    Topics: Medicine , Biology
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1146/annurev.ph.50.030188.002115
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  • 2
    Electronic Resource
    Electronic Resource
    Intracellular concentration of elements in normal and dystrophic skeletal muscles of the chicken (1980)
    New York, NY [u.a.] : Wiley-Blackwell
    Journal of Cellular Physiology 103 (1980), S. 193-200 
    Details
    ISSN: 0021-9541
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Medicine
    Notes: In this study, the intracellular concentrations of six elements (mmole/kg dry weight) were directly measured in the muscle fibers of pectoralis major muscles of eight week old, genetically dystrophic and normal chickens by the X-ray microanalysis technique. The extent of muscle degeneration was evaluated by morphometric measurements of muscle fiber diameter and other histological changes. A significant increase in the concentration of intracellular sodium and chlorine was evident in dystrophic muscles. The concentration of intracellular sodium was 127.0 ± 35.0 in the muscle fibers of dystrophic chicks compared to 65.7 ± 16.5 in normal controls. The concentration of chlorine was 90.5 ± 27.5 and 54.1 ± 5.5 in the muscle fibers of dystrophic and normal chicks respectively. The intracellular concentrations of potassium, magnesium, phosphorous, and sulfur remained unchanged in the dystrophic condition. Morphometric studies revealed that the dystrophic pectoralis muscles contain fewer but thicker fibers per unit area compared to normal pectoralis muscles. The importance of these findings are discussed in relation to the results of earlier investigations.
    Additional Material: 1 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/jcp.1041030204
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  • 3
    Electronic Resource
    Electronic Resource
    Effects of millimeter-wave radiation on monolayer cell cultures. II. Scanning and transmission electron microscopy (1981)
    New York, NY [u.a.] : Wiley-Blackwell
    Bioelectromagnetics 2 (1981), S. 141-150 
    Details
    ISSN: 0197-8462
    Keywords: millimeter-wave radiation ; BHK-21/C13 cells in monolayer culture ; scanning electron microscopy ; transmission electron microscopy ; Life and Medical Sciences ; Occupational Health and Environmental Toxicology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Physics
    Notes: Both thermal and athermal effects of millimeter-wave radiation on BHK-21/C13 cells were sought using scanning and transmission electron microscopy in conjunction with an in vitro technique that allows direct exposure of monolayer cultures to high average power densities. Culture dishes were irradiated by placing them on the open end of an E- or U-band wave guide. This technique exposes different regions of the cell monolayer lying along the longer axis of the wave guide aperture to varying power densities ranging from zero at each edge to twice the average power density at the center.Cell ultrastructure was unaffected by microwave radiation for 1 hour (41.8 or 74.0 GHz, average power densitites = 320 or 450 mW/cm2, respectively) with or without cooling by rapid recirculation of the culture medium. Temperature in recirculated cultures was held at 37.2 °C, and that in noncooled cultures never exceeded 42 °C during irradiation at either power density. In contrast, cell morphology was affected by microwave exposure whenever irradiation conditions were altered so that the temperature of the monolayer reached or exceeded 44.5 °C. Ultrastructural alterations included breakage of cell processes, progressive detachment of cells from the substrate, increased clumping of heterochromatin in the nuclei, and the appearance of large empty vesicles in the cytoplasm. Such morphological changes resulted from either application of higher average power densities or irradiation at the power densities described above at a higher ambient temperature (〉38.5°C).
    Additional Material: 5 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/bem.2250020205
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  • 4
    Electronic Resource
    Electronic Resource
    Electron microscopic investigation of polyamidohydrazide solutions (1985)
    Weinheim : Wiley-Blackwell
    Acta Polymerica 36 (1985), S. 624-627 
    Details
    ISSN: 0323-7648
    Keywords: Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology , Physics
    Description / Table of Contents: Unter Hernziehung unterschiedlicher Präparationsmethoden wurde die Struktur verdünnter und konzentrierter (0,01 bis 9,8%) Lösungen des starkettigen Polyamidohydrazid (PAH) mittels Elektronenmikroskopie in zwei Lösungsmitteln (DMSO und DMAA) untersucht. Beginnend mit der Konzentration 0,01% erfolgt unterschiedliche Strukturierung in diesen Lösungsmitteln, die bezüglich des Polymers eine unterschiedliche Güte aufweisen. Die Ergebnisse wurden früheren Untersuchungen zur Rheologie konzentrierter PAH-Lösungen in den genannten Lösungsmitteln gegenüber gestellt.
    Notes: The structure of dilute and concentrated solutions (0.01-9.8%) of rigid-chain polyamidohydrazide (PAH) in dimethylsulphoxide and dimethylacetamide was investigated by electron microscopy using various preparation techniques. Starting with a 0.01% concentration, PAH shows two distinct types of structuration in the solvents. The results are compared with previously studied rheological properties of PAH in these solvents.
    Additional Material: 5 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/actp.1985.010361110
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  • 5
    Electronic Resource
    Electronic Resource
    Synthesis of fibre-forming copolymers of acrylonitrile with acrylates in systems based on lithium alkoxides (1984)
    Weinheim : Wiley-Blackwell
    Acta Polymerica 35 (1984), S. 65-67 
    Details
    ISSN: 0323-7648
    Keywords: Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology , Physics
    Description / Table of Contents: Die Copolymerisation von Acrylnitril und Acrylaten wurde in Dimethylformamid bei hohem Acrylnitril/Acrylat-Verhältnis im Temperaturbereich von -50 bis +10°C durch Lithiumalkoxide initiiert. Die Bedingungen zur direkten Präparation von Spinnlösungen der Copolymere wurden erarbeitet. Das Lösungsspinnen dieser Copolymere durch Orientierungsfällung ergab Fasern mit hohen Festigkeitswerten.
    Notes: The copolymerization of acrylonitrile with acrylates has been initiated by lithium alkoxides in dimethylformamide at a high acrylonitrile/acrylate ratio over the temperature range from -50 to 10°C. The conditions for a direct preparation of spinning solutions of the copolymers were determined. The solution-spinning of these copolymers by orientational precipitation yielded fibres exhibiting high strength properties.
    Additional Material: 3 Tab.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/actp.1984.010350115
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  • 6
    Electronic Resource
    Electronic Resource
    Paleogeographic Interpretation: With an Example From the Mid-Cretaceous (1985)
    Palo Alto, Calif. : Annual Reviews
    Annual Review of Earth and Planetary Sciences 13 (1985), S. 385-428 
    Details
    ISSN: 0084-6597
    Source: Annual Reviews Electronic Back Volume Collection 1932-2001ff
    Topics: Geosciences , Physics
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1146/annurev.ea.13.050185.002125
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  • 7
    Electronic Resource
    Electronic Resource
    Sealing technique for static coating of large bore capillary columns (1981)
    Weinheim : Wiley-Blackwell
    Journal of High Resolution Chromatography 4 (1981), S. 588-588 
    Details
    ISSN: 0935-6304
    Keywords: Capillary columns ; End sealing ; Chemistry ; Analytical Chemistry and Spectroscopy
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/jhrc.1240041113
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  • 8
    Electronic Resource
    Electronic Resource
    Determination of chlorpromazine and its major metabolites by gas chromatography/mass spectrometry: Application to biological fluids (1985)
    Chichester : Wiley-Blackwell
    Biological Mass Spectrometry 12 (1985), S. 707-713 
    Details
    ISSN: 1052-9306
    Keywords: Chemistry ; Analytical Chemistry and Spectroscopy
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Notes: A method for the quantitative determination of chlorpromazine and five of its major metabolites in a single sample of biological fluid in the ng/ml range has been developed utilizing gas chromatography/mass spectrometry with selected ion recording. The assay is highly specific and quantification is accomplished by an inverse stable isotope dilution technique, using deuterium-labeled variants of the compounds as internal standards. In this way the concentrations of chlorpromazine and five of its major metabolites (the sulfoxide, the N-oxide, the monodemethylated, the didemethylated, and the 7-hydroxylated compounds) can be determined in biological fluids. Levels in humans have been measured both in plasma and in red blood cells and are compared to those found in related in vitro studies.
    Additional Material: 2 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/bms.1200121207
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  • 9
    Electronic Resource
    Electronic Resource
    Large-scale production of monoclonal antibodies in suspension culture (1988)
    New York, NY [u.a.] : Wiley-Blackwell
    Biotechnology and Bioengineering 32 (1988), S. 993-1000 
    Details
    ISSN: 0006-3592
    Keywords: Chemistry ; Biochemistry and Biotechnology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: Monoclonal antibodies are being manufactured for clinical trials in suspension culture at the 1300-L scale. Suspension culture offers some advantages relative to high-density mammalian cell culture methods; in particular, the ability to closely monitor the behavior of cells in a homogeneous environment. Computer control and on-line mass spectrography of exit gases provide instantaneous information about the culture metabolic activity. Air sparging and agitation by marine impeller provide aeration sufficient to maintain a constant dissolved oxygen tension at cell concentrations up to 5.0 × 106 cells/mL without causing apparent cell damage.
    Additional Material: 8 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/bit.260320807
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  • 10
    Electronic Resource
    Electronic Resource
    A microfibril-generating factor from the cellulase of Trichoderma reesei (1988)
    New York, NY [u.a.] : Wiley-Blackwell
    Biotechnology and Bioengineering 31 (1988), S. 321-327 
    Details
    ISSN: 0006-3592
    Keywords: Chemistry ; Biochemistry and Biotechnology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: A combination of ionic strength reduction and diafiltration of Trichoderma reesei cellulate complex through a hollow fiber apparatus of 5000 molecular weight (MW) cutoff and subsequent passage of filtrate over a Spherogel-TSK 3000-SW column provided extracts that had the ability to generate microfibrils in filter paper and to disrupt filter paper and corn leaf tissue. Milligram quantities of material obtained from these extracts released small amounts of soluble carbohydrate from filter paper, required ferric iron for increased activity, and contained amino acids. Short fiber formation and disruption of filter paper during interaction with these extracts was enhanced by prior acid treatment and eliminated by prior base treatment. The amount of soluble carbohydrate hydrolyzed in 24 h from filter paper by whole cellulase complex was not changed by first disrupting the substrate with the extracts.
    Additional Material: 5 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/bit.260310407
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