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  • GEOPHYSICS  (8)
  • Immunohistochemistry  (4)
  • 1985-1989  (2)
  • 1980-1984  (7)
  • 1965-1969  (3)
  • 1960-1964
  • 1950-1954
  • 1935-1939
  • 1920-1924
  • 1
    Electronic Resource
    Electronic Resource
    Glucagon-related peptides in the rat hypothalamus (1986)
    Springer
    Cell & tissue research 246 (1986), S. 71-75 
    Details
    ISSN: 1432-0878
    Keywords: Glucagon-related peptides ; Rat hypothalamus ; Radioimmunochemistry ; Immunohistochemistry ; Food deprivation ; Rat
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary Immunohistochemically, nerve fibers and terminals reacting with anti-N-terminal-specific but not with anti-C-terminal-specific glucagon antiserum were observed in the following rat hypothalamic regions: paraventricular nucleus, supraoptic nucleus, anterior hypothalamus, arcuate nucleus, ventromedial hypothalamic nucleus and median eminence. Few fibers and terminals were demonstrated in the lateral hypothalamic area and dorsomedial hypothalamic nucleus. Radioimmunoassay data indicated that the concentration of gut glucagon-like immunoreactivity was higher in the ventromedial nucleus than in the lateral hypothalamic area. In food-deprived conditions, this concentration increased in both these parts. This was also verified in immunostained preparations in which a marked enhancement of gut glucagon-like immunoreactivity-containing fibers and terminals was observed in many hypothalamic regions. Several immunoreactive cell bodies were found in the ventromedial and arcuate nuclei of starved rats. Both biochemical and morphological data suggest that glucagon-related peptides may act as neurotransmitters or neuromodulators in the hypothalamus and may be involved in the central regulatory mechanism related to feeding behavior and energy metabolism.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00219001
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    Paper (German National Licenses)
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  • 2
    Electronic Resource
    Electronic Resource
    Immunohistochemical demonstration of the distribution of serotonin neurons in the brainstem of the rat and cat (1982)
    Springer
    Cell & tissue research 224 (1982), S. 247-267 
    Details
    ISSN: 1432-0878
    Keywords: Serotonin ; Brainstem ; Immunohistochemistry ; Rat ; Cat
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary The morphological characteristics and distribution of the somata of serotonin-containing neurons in the brainstem of rats and cats were studied by use of the peroxidase-anti peroxidase (PAP) immunohistochemical method employing highly specific antibodies to serotonin. Antibodies were raised in rabbits against an antigen prepared by coupling serotonin to bovine thyroglobulin and using formaldehyde as the coupling reagent. The distribution pattern of serotonin neurons observed in the present material is essentially in agreement with that described by other investigators who used the Falck-Hillarp method. In addition, this immunohistochemical technique revealed serotonin-containing perikarya in the following regions: 1) the periaqueductal gray, especially lateral to the nucleus raphe dorsalis, 2) the nucleus interpeduncularis, 3) the nucleus parabrachialis ventralis and dorsalis, 4) the field of the lemniscus lateralis, and 5) the reticular formation of the pons and medulla oblongata. The described immunohistochemical procedure makes it possible to study central serotonin neurons in detail without pharmacological pretreatment. The wide distribution of serotonin neurons demonstrated in this study should be considered when interpreting experiments dealing with the serotonin system.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00216872
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    Paper (German National Licenses)
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  • 3
    Electronic Resource
    Electronic Resource
    Immunohistochemical demonstration of serotonin-containing nerve fibers in the cerebellum (1982)
    Springer
    Cell & tissue research 226 (1982), S. 1-12 
    Details
    ISSN: 1432-0878
    Keywords: Serotonin-immunoreactive nerve fibers ; Cerebellum ; Cat ; Rat ; Immunohistochemistry
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary The localization of serotonin (5-HT)-immunoreactive nerve fibers in the cerebellum of the rat and cat was investigated by means of the peroxidase-anti-peroxidase (PAP) method using highly specific antibodies to 5-HT. Serotonin-containing nerve fibers were distributed throughout the entire cerebellum including the deep cerebellar nuclei, while 5-HT-positive neuronal somata were not detected in the cerebellum of either species. A different pattern of 5-HT innervation was found among the three layers of the cerebellar cortex. There were also interspecific differences in the pattern of distribution of 5-HT. In the rat, the pool of 5-HT nerve fibers mainly consisted of tangential elements, which were predominant in the molecular layer, while in the cat only a few 5-HT fibers were found in the molecular layer of the cerebellar cortex; dense networks of 5-HT nerve fibers were present in the granular layer. Some differences are evident in the pattern of distribution of 5-HT fibers in cerebellar regions classified on an anatomical and functional basis.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00217077
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  • 4
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    Perivascular microglial cells of the CNS are bone marrow-derived and present antigen in vivo (1988)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1988-01-15
    Description: A crucial question in the study of immunological reactions in the central nervous system (CNS) concerns the identity of the parenchymal cells that function as the antigen-presenting cells in that organ. Rat bone marrow chimeras and encephalitogenic, major histocompatability--restricted T-helper lymphocytes were used to show that a subset of endogenous CNS cells, commonly termed "perivascular microglial cells," is bone marrow-derived. In addition, these perivascular cells are fully competent to present antigen to lymphocytes in an appropriately restricted manner. These findings are important for bone marrow transplantation and for neuroimmunological diseases such as multiple sclerosis.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Hickey, W F -- Kimura, H -- KO7-NS0087/NS/NINDS NIH HHS/ -- New York, N.Y. -- Science. 1988 Jan 15;239(4837):290-2.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Department of Pathology and Laboratory Medicine, University of Pennsylvania, Philadelphia, PA 19104-6079.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/3276004" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Antigen-Presenting Cells/*immunology ; Astrocytes/immunology ; Bone Marrow/*immunology ; Bone Marrow Transplantation ; Central Nervous System/blood supply/*immunology/pathology ; Chimera ; Encephalomyelitis, Autoimmune, Experimental/immunology/pathology ; Endothelium/immunology ; Graft vs Host Disease/immunology ; Histocompatibility Antigens/analysis/immunology ; Immunohistochemistry ; Multiple Sclerosis/immunology/pathology ; Neuroglia/*immunology ; Rats ; Rats, Inbred Lew ; T-Lymphocytes/immunology
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
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    PAPER CURRENT
  • 5
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    Jikiken /EXOS-B/ observation of Siple transmissions (1981)
    In:  Other Sources
    Details
    Publication Date: 2011-08-18
    Description: Preliminary results of observations by the Japanese magnetospheric satellite Jikiken (EXOS-B) of Siple transmissions and VLF emissions triggered by the Siple signals are reviewed. The experiments discussed were carried out in July, August, and September of 1979 and in December 1979 and January 1980. Only four events concentrated within the period from August 14 to 18 were found in which triggered emissions were associated with Siple transmissions. The electron distributions observed on the equatorial crossing passes, when Siple triggered emissions were detected, suggest that the cyclotron resonance condition is satisfied for Siple signals and electrons of energy around 1 keV or less, provided the interaction region is inside the plasmapause. It is noted that if these emissions were generated outside the plasmapause, electron energies much higher than 10 keV would be necessary for the cyclotron interaction, which were above the range of the measurements. For the high latitude passes of August 14 and 17, the electron fluxes were found to be very small.
    Keywords: GEOPHYSICS
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    NASA TECHNICAL REPORTS
  • 6
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    An interpretation of transverse whistlers. (1965)
    In:  Other Sources
    Details
    Publication Date: 2019-05-30
    Description: Whistler in Alouette I satellite VLF RECORDINGS, variation of time delay with frequency given by Eckersley law time delay and additive correction term
    Keywords: GEOPHYSICS
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    NASA TECHNICAL REPORTS
  • 7
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    Effects of ions on whistler-mode ray tracing. (1966)
    In:  Other Sources
    Details
    Publication Date: 2019-05-30
    Description: Smith subprotonospheric whistlers and digital computation of ion effects on whistler-mode ray tracing
    Keywords: GEOPHYSICS
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    NASA TECHNICAL REPORTS
  • 8
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    Lower hybrid resonance noise and a new ionospheric duct. (1966)
    In:  Other Sources
    Details
    Publication Date: 2019-05-30
    Description: Lower hybrid resonance in VLF range in satellites, noting noise emission due to trapping of electromagnetic wave propagation in transverse magnetic field
    Keywords: GEOPHYSICS
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    NASA TECHNICAL REPORTS
  • 9
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    EXOS-B/Siple station VLF wave-particle interaction experiments. I - General description and wave-particle correlations (1983)
    In:  Other Sources
    Details
    Publication Date: 2019-06-28
    Description: The EXOS-B/Siple Station joint experiment on the triggering of VLF emissions by man-made signals causing some form of wave-particle interactions in the magnetosphere is presented, and results concerning wave-particle correlations are reported. In situ measurements of both energetic electron flux and VLF waves were made near the meridian connecting Siple Station, Antarctica with Roberval, Quebec, Canada in campaigns during July through September, 1979 and December 1979 through January 1980 at times of VLF transmission from Siple. Strong observed signals were found to be well correlated with a pancake pitch angle distribution of 0.3 to 6.9-keV electrons, and to exhibit a positive linear growth rate. Artificially stimulated emissions were observed to be accompanied by large electron fluxes in all energy channels in the equatorial interaction region, although the measured pitch angle distribution was not highly anisotropic. Results may be interpreted by the amplification of Siple signals by the cyclotron instability due to high pitch angle anisotropy (pancake distribution) and the triggering of emissions in the presence of high electron fluxes with some anisotropy and a sufficiently strong signal.
    Keywords: GEOPHYSICS
    Type: Journal of Geophysical Research; 88; Jan. 1
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    NASA TECHNICAL REPORTS
  • 10
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    High altitude satellite observations of signals from the Siple transmitter (1980)
    In:  Other Sources
    Details
    Publication Date: 2019-06-28
    Keywords: GEOPHYSICS
    Type: NASA-CR-173039 , NAS 1.26:173039
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    NASA TECHNICAL REPORTS
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