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  • 1
    Publication Date: 1994-11-04
    Description: The SecA protein is an essential, azide-sensitive component of the bacterial protein translocation machinery. A SecA protein homolog (CPSecA) now identified in pea chloroplasts was purified to homogeneity. CPSecA supported protein transport into thylakoids, the chloroplast internal membrane network, in an azide-sensitive fashion. Only one of three pathways for protein transport into thylakoids uses the CPSecA mechanism. The use of a bacteria-homologous mechanism in intrachloroplast protein transport provides evidence for conservative sorting of proteins within chloroplasts.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Yuan, J -- Henry, R -- McCaffery, M -- Cline, K -- 1 R01 GM46951/GM/NIGMS NIH HHS/ -- New York, N.Y. -- Science. 1994 Nov 4;266(5186):796-8.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Plant Molecular and Cellular Biology Program, University of Florida, Gainesville 32611.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/7973633" target="_blank"〉PubMed〈/a〉
    Keywords: Adenosine Triphosphatases/metabolism ; Azides/pharmacology ; Bacterial Proteins/metabolism ; Base Sequence ; Biological Transport/drug effects ; Carrier Proteins/chemistry/isolation & purification/*metabolism ; Chloroplast Proteins ; Chloroplasts/*metabolism ; *Escherichia coli Proteins ; Intracellular Membranes/metabolism ; *Membrane Proteins ; *Membrane Transport Proteins ; Molecular Sequence Data ; Peas ; Photosynthetic Reaction Center Complex Proteins/*metabolism ; *Photosystem II Protein Complex ; Plant Proteins/chemistry/isolation & purification/*metabolism ; Plastocyanin/*metabolism ; Sodium Azide ; Symbiosis
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 2
    Publication Date: 1994-02-11
    Description: Interleukin-1 beta converting enzyme (ICE) is a mammalian homolog of CED-3, a protein required for programmed cell death in the nematode Caenorhabditis elegans. The activity of ICE can be specifically inhibited by the product of crmA, a cytokine response modifier gene encoded by cowpox virus. Microinjection of the crmA gene into chicken dorsal root ganglion neurons was found to prevent cell death induced by deprivation of nerve growth factor. Thus, ICE is likely to participate in neuronal death in vertebrates.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Gagliardini, V -- Fernandez, P A -- Lee, R K -- Drexler, H C -- Rotello, R J -- Fishman, M C -- Yuan, J -- New York, N.Y. -- Science. 1994 Feb 11;263(5148):826-8.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Cardiovascular Research Center, Massachusetts General Hospital, Charlestown 02129.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/8303301" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; *Apoptosis ; Caspase 1 ; Cells, Cultured ; Chickens ; Ganglia, Spinal ; Gene Expression ; Metalloendopeptidases/*genetics/physiology ; Microinjections ; Nerve Growth Factors/pharmacology ; Neurons, Afferent/*cytology/metabolism ; Proto-Oncogene Proteins/genetics/physiology ; Proto-Oncogene Proteins c-bcl-2 ; Serpins/*genetics/physiology ; *Viral Proteins
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 3
    Publication Date: 1994-01-07
    Description: Interleukin-6 (IL-6), leukemia inhibitory factor, oncostatin M, interleukin-11, and ciliary neurotrophic factor bind to receptor complexes that share the signal transducer gp130. Upon binding, the ligands rapidly activate DNA binding of acute-phase response factor (APRF), a protein antigenically related to the p91 subunit of the interferon-stimulated gene factor-3 alpha (ISGF-3 alpha). These cytokines caused tyrosine phosphorylation of APRF and ISGF-3 alpha p91. Protein kinases of the Jak family were also rapidly tyrosine phosphorylated, and both APRF and Jak1 associated with gp130. These data indicate that Jak family protein kinases may participate in IL-6 signaling and that APRF may be activated in a complex with gp130.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Lutticken, C -- Wegenka, U M -- Yuan, J -- Buschmann, J -- Schindler, C -- Ziemiecki, A -- Harpur, A G -- Wilks, A F -- Yasukawa, K -- Taga, T -- New York, N.Y. -- Science. 1994 Jan 7;263(5143):89-92.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Institute for Biochemistry, RWTH Aachen, Germany.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/8272872" target="_blank"〉PubMed〈/a〉
    Keywords: *Antigens, CD ; Base Sequence ; Cytokine Receptor gp130 ; Cytokines/pharmacology ; DNA-Binding Proteins/*metabolism ; Humans ; Interferon-Stimulated Gene Factor 3 ; Interferon-Stimulated Gene Factor 3, gamma Subunit ; Interferon-gamma/pharmacology ; Interleukin-6/*pharmacology ; Janus Kinase 1 ; Membrane Glycoproteins/*metabolism ; Molecular Sequence Data ; Phosphorylation ; Protein-Tyrosine Kinases/*metabolism ; STAT1 Transcription Factor ; STAT3 Transcription Factor ; Signal Transduction ; *Trans-Activators ; Transcription Factors/metabolism ; Tumor Cells, Cultured ; Tyrosine/metabolism
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 4
    Electronic Resource
    Electronic Resource
    [S.l.] : American Institute of Physics (AIP)
    Journal of Applied Physics 74 (1993), S. 2388-2396 
    ISSN: 1089-7550
    Source: AIP Digital Archive
    Topics: Physics
    Notes: Part I of this paper presents the modified laser spallation technique for measuring the tensile strength of planar interfaces, using a Doppler displacement interferometer. In this technique, a laser-produced compressive stress pulse in the substrate, reflecting from the coating's free surface pulls the interface in tension and leads to its failure if the tensile amplitude is high enough. The current technique is an improvement over the previous one, since the interface stress is determined directly by recording the coating or substrate free-surface velocities using a laser displacement interferometer. The recorded surface velocity is related to the interface stress via an elastic wave equation simulation. The process of coating spallation is investigated, and the effect of the stress pulse profile and the coating and substrate characteristics on the interface tensile stress is studied using the simulation. Several interface stress charts are given for wider applicability of the modified technique.
    Type of Medium: Electronic Resource
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  • 5
    Electronic Resource
    Electronic Resource
    [S.l.] : American Institute of Physics (AIP)
    Journal of Applied Physics 70 (1991), S. 2402-2407 
    ISSN: 1089-7550
    Source: AIP Digital Archive
    Topics: Physics
    Notes: Modeling the cutoff frequency (fT) of the advanced bipolar transistors at avalanche breakdown has been developed. The analytical equations developed account for temperature and impact ionization effects on fT and high-current effects at the collector-base junction. Process sensitivity of the collector charging time at the avalanche breakdown regime has been examined. The experimental data reported in the literature are compared in support of the model. Good agreement between the model prediction and measurement is obtained.
    Type of Medium: Electronic Resource
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  • 6
    Electronic Resource
    Electronic Resource
    [S.l.] : American Institute of Physics (AIP)
    Journal of Applied Physics 68 (1990), S. 1247-1251 
    ISSN: 1089-7550
    Source: AIP Digital Archive
    Topics: Physics
    Notes: Diamond particles 10–500 nm in diameter were produced by microwave-assisted combustion of acetylene in oxygen. Both premixed and diffusion flame configurations were investigated. A mixture of cubic and hexagonal polytypes of diamond were identified. Larger particle sizes were observed at lower reactor pressure and higher C to O atomic ratios. C to O atomic ratios between 0.83 and 1.0 produced crystalline diamond powder while other ratios produced graphite, soot, and amorphous carbon phases. Diamond formation was not observed when reaction pressures were above 150 Torr.
    Type of Medium: Electronic Resource
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  • 7
    Electronic Resource
    Electronic Resource
    [S.l.] : American Institute of Physics (AIP)
    Journal of Applied Physics 68 (1990), S. 5911-5912 
    ISSN: 1089-7550
    Source: AIP Digital Archive
    Topics: Physics
    Notes: A more accurate intrinsic concentration was suggested recently. Discrepancies between using the conventional and the more accurate intrinsic concentrations on bipolar transistor modeling are assessed in this study. Our calculations show that the conventional intrinsic concentration overestimates the collector and base currents by a factor of 1.5 to 2 but affects less severely the steady-state current gain.
    Type of Medium: Electronic Resource
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  • 8
    Electronic Resource
    Electronic Resource
    [S.l.] : American Institute of Physics (AIP)
    Journal of Applied Physics 75 (1994), S. 6501-6503 
    ISSN: 1089-7550
    Source: AIP Digital Archive
    Topics: Physics
    Notes: An electron-microscopy-based technique of electron-energy-loss spectroscopy (EELS) has been used to characterize electronic and magnetic properties of ultrathin Fe films grown on GaAs(100) surface, as a function of the film thickness. Large-area electron transparent membranes for microscopic analysis are prepared by ion-beam thinning or chemical etching from the substrate side, and the top surface of the ultrathin Fe film is protected by a thin Cr layer. Analysis of the Fe 2p, Cr 2p, and O 1s absorption spectra confirms that only the Cr layer is oxidized. The local magnetic moments of the ultrathin Fe films are deduced from the "white line'' branching ratio in the Fe 2p absorption spectra. For Fe films as thin as 150 A(ring), the magnetic moment is not different from that found in bulk α-Fe. For a 70-A(ring) Fe film, the local magnetic moment is enhanced although the average magnetization is reduced. As doping is suspected to be the cause for the departure from bulk α-Fe properties. In the case where the 50-A(ring) film is polycrystalline and discontinuous, spatially resolved EELS has been used to distinguish small island clusters from large crystalline particles. The large particles are α-Fe crystallites and the islands are probably also heavily affected by As doping.
    Type of Medium: Electronic Resource
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  • 9
    Electronic Resource
    Electronic Resource
    Woodbury, NY : American Institute of Physics (AIP)
    Applied Physics Letters 59 (1991), S. 546-548 
    ISSN: 1077-3118
    Source: AIP Digital Archive
    Topics: Physics
    Notes: The effects of heteroatom addition on the nucleation of solid carbon in a low-pressure plasma reactor were investigated. Silane or diborane were added to acetylene mixed in hydrogen or argon. Oxygen was added to some of the diborane containing gas mixtures. Silane containing mixtures resulted in powder comprised of weakly bonded amorphous hydrogenated carbon-silicon material. The addition of diborane resulted in substantial production of diamond particles, 5 to 450 nm in diameter, under the conditions that show no diamond formation without diborane present. The observed yield of the oxidation-resistant powder produced in boron-containing mixtures reached 1.3 mg/h with the linear growth rates of diamond particles on the order of 102–104 μm/h. Implication of these results to interstellar dust formation is discussed.
    Type of Medium: Electronic Resource
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  • 10
    Electronic Resource
    Electronic Resource
    Palo Alto, Calif. : Annual Reviews
    Annual Review of Cell and Developmental Biology 7 (1991), S. 663-698 
    ISSN: 0743-4634
    Source: Annual Reviews Electronic Back Volume Collection 1932-2001ff
    Topics: Biology , Medicine
    Type of Medium: Electronic Resource
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