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  • Protoporphyrinogen oxidase  (1)
  • goal oriented approach  (1)
  • 1990-1994  (2)
  • 1
    Electronic Resource
    Electronic Resource
    Springer
    Software quality journal 1 (1992), S. 81-100 
    ISSN: 1573-1367
    Keywords: education ; measurement ; metrics ; models ; goal oriented approach ; data collection ; data analysis ; measurement programme
    Source: Springer Online Journal Archives 1860-2000
    Topics: Computer Science
    Notes: Abstract This paper deals with a perceived need for a well-balanced education (or in some cases re-education) in the subject of software engineering measurement, more commonly although less accurately known as software metrics. This need was confirmed by a major survey of both industry and academia conducted in 1989. Software metrics have received a lot of bad press in the past, mainly due to some much criticized early work in so-called complexity metrics. A result of this has been scepticism or lack of interest in other areas of the wider subject of software engineering measurement, which covers not only models and measures applicable to software products, but also those applicable to the processes and resources involved in software production. The ideas and work described in this paper have arisen out of the ESPRIT project ‘METKIT’, which has produced educational material about software engineering measurement for use in both industry and academia. This paper also describes the material designed for academia, most of which has now been tested in 12 European academic institutions. The material concentrates on principles and examples rather than prescribing the use of particular models and measures. This material has been widely publicized; the response to it has been encouraging so far and it appears that the material will have a significant impact towards getting the subject taught much more widely, and in a more balanced way.
    Type of Medium: Electronic Resource
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  • 2
    ISSN: 0749-1581
    Keywords: Through-space coupling ; Tetrahydroindazoles ; Protoporphyrinogen oxidase ; Molecular mechanics ; Chemistry ; Analytical Chemistry and Spectroscopy
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Notes: 1H, 13C and 19F NMR experiments for a series of 3-alkyl-2-phenyl-4,5,6,7-tetrahydroindazoles revealed a six-bond through-space coupling between the ortho-fluorine and the hydrogen or fluorine atom of the position 3-alkyl group. This was further supported by NOE experiments. Molecular mechanics calculations on a representative structure indicated that several low energy conformers met the fluorine-carbon distance constraint suggested by the NMR data, and dynamic annealing experiments produced a conformer which was in complete agreement with the NMR data. This through-space interaction is speculated to be a result of repulsion between N-1 of the tetrahydroindazole and the ortho-fluorine lone pair electrons.
    Additional Material: 3 Tab.
    Type of Medium: Electronic Resource
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