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  • 1
    Electronic Resource
    Electronic Resource
    Short-crested wave-induced soil response in a porous seabed of infinite thickness (1993)
    New York, NY [u.a.] : Wiley-Blackwell
    International Journal for Numerical and Analytical Methods in Geomechanics 17 (1993), S. 553-576 
    Details
    ISSN: 0363-9061
    Keywords: Engineering ; Engineering General
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Architecture, Civil Engineering, Surveying , Geosciences
    Notes: Waves reflecting obliquely from structures establish short-crested waves which are conducive to scour of the bed adjacent to them. The pore pressures and effective stresses induced by this wave system are derived analytically for an unsaturated, anisotropic soil matrix of infinite depth in a three-dimensional domain. Verification is available by the solutions being readily reduced to the two-dimensional cases of the progressive and standing wave, for which some closed-form solutions are available. It is shown that wave obliquity is coupled with soil permeability. The effects of wave obliquity, relative water depth, soil stiffness and soil permeability on wave-induced pore pressure are discussed in detail.
    Additional Material: 11 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/nag.1610170803
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  • 2
    Electronic Resource
    Electronic Resource
    Wave-induced soil response in an unsaturated anisotropic seabed of finite thickness (1994)
    New York, NY [u.a.] : Wiley-Blackwell
    International Journal for Numerical and Analytical Methods in Geomechanics 18 (1994), S. 785-807 
    Details
    ISSN: 0363-9061
    Keywords: Engineering ; Engineering General
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Architecture, Civil Engineering, Surveying , Geosciences
    Notes: An analytical solution for the wave-induced soil response is developed for a seabed of finite thickness subject to a three-dimensional (3-D) wave system produced by two intersecting waves of equal properties. These 3-D exact solutions for the pore pressure and effective stresses, proposed for a non-cohesive soil matrix of finite depth in a homogeneously unsaturated and anisotropic condition, are readily reducible to the limiting two-dimensional cases of progressive and standing waves, for which no explicit solutions are available for finite thickness. The effects of soil isotropy, degree of saturation, seabed thickness and grain size on the wave-induced pore pressure are discussed in detail. The explicit solutions presented in this study for the wave-induced pore pressure and effective stresses should benefit the laboratory experiments and field monitoring programs carried out in soil of finite depth.
    Additional Material: 11 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/nag.1610181104
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  • 3
    Electronic Resource
    Electronic Resource
    Numerical modelling of crack propagation using multi-variable and breakable finite elements (1990)
    New York, NY [u.a.] : Wiley-Blackwell
    Communications in Applied Numerical Methods 6 (1990), S. 215-222 
    Details
    ISSN: 0748-8025
    Keywords: Engineering ; Engineering General
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Mathematics , Technology
    Notes: In this study, the advantage of the multi-variable finite-element model based on the generalized virtual work principle is described. The model has been applied to the elasto-plastic fracture analysis with finite deformations. Using the multi-variable finite-element model with a‘breakable finite-element’ concept, the authors proposed an algorithm which can more accurately simulate the crack growth. Numerical examples illustrate that the algorithm presented can be successfully used to predict whether the crack growth is stable or unstable. The rupture effective strain is considered as a fracture criterion, and some comparisons between various criteria are also provided.
    Additional Material: 5 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/cnm.1630060308
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  • 4
    Electronic Resource
    Electronic Resource
    On the use of the reach-back characteristics method for calculation of dispersion (1991)
    Chichester : Wiley-Blackwell
    International Journal for Numerical Methods in Fluids 12 (1991), S. 225-235 
    Details
    ISSN: 0271-2091
    Keywords: Advection ; Diffusion ; Numerical simulation ; Engineering ; Engineering General
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Notes: The Holly-Preissmann two-point finite difference scheme (HP method) has been popularly used for solving the advection equation. The key idea of this scheme is to solve the dependent variable (i.e. the concentration for the pollutant transport problem) by the method of characteristics with the use of cubic interpolation on the spatial axis. The interpolating polynomials of higher order are constructed by use of the dependent variable and its derivatives at two adjacent grid points. In this paper a new interpolating technique is introduced for incorporation with the Holly-Preissmann two-point method. The new method is denoted herein as the Holly-Preissmann reach-back method (HPRB) and allows the characteristics to project back several time steps beyond the present time level. Through stability analyses it has been observed that the increase of the reach-back time step numbers for the characteristics indeed reduces the numerical damping and dispersive phenomena. A schematic model has been constructed to demonstrate the merits of this new technique for the calculation of the pure advection and dispersion equations. Numerical experiments and comparisons with analytical solutions which support and demonstrate this new technique are presented.
    Additional Material: 6 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/fld.1650120303
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  • 5
    Electronic Resource
    Electronic Resource
    Assessment of TVD schemes for inviscid and turbulent flow computation (1991)
    Chichester : Wiley-Blackwell
    International Journal for Numerical Methods in Fluids 12 (1991), S. 161-177 
    Details
    ISSN: 0271-2091
    Keywords: Convection approximation ; Total variation diminishing schemes ; Shock ; Turbulent and inviscid flows ; Engineering ; Engineering General
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Notes: A systematic study has been conducted to assess the performance of the TVD schemes for practical flow computation. The viewpoint adopted here is to treat the TVD schemes as a combination of the standard central difference scheme with numerical dissipation terms. The controlled amount of numerical dissipation modifies the computed fluxes to ensure that the solution is oscillation-free. Four variants of TVD schemes, two with upwind dissipation terms and two with symmetric dissipation terms, have been studied and compared with the conventional Beam-Warming scheme for inviscid and turbulent axisymmetric flow computations. The results obtained show that all four variants can accurately resolve the shock and flow profiles with fewer grid points than the Beam-Warming scheme. The convergence rates of the TVD schemes are also substantially superior to that of the Beam-Warming scheme. The combination of high accuracy, good robustness and improved computational efficiency offered by the TVD schemes makes them attractive for computing high-speed flow with shocks. In terms of the relative performances it is found that the symmetric schemes converge slightly faster but that the upwind schemes are less sensitive to the number of grid points being employed.
    Additional Material: 12 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/fld.1650120205
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  • 6
    Electronic Resource
    Electronic Resource
    Applications of boundary integral equation methods for two-dimensional non-linear water wave problems (1992)
    Chichester : Wiley-Blackwell
    International Journal for Numerical Methods in Fluids 15 (1992), S. 1119-1141 
    Details
    ISSN: 0271-2091
    Keywords: Integral equation ; Overturning progressive waves ; Breaking standing waves ; Sloshing ; Engineering ; Engineering General
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Notes: On the basis of the integral equation approach, numerical algorithms for solving non-linear water wave problem are presented. The free surface flow is assumed to be irrotational. Two different Green functions are used in the integral equations. The non-linear free-surface boundary conditions are treated by a time-stepping Lagrangian technique. Several numerical examples are given, including permanent periodic waves, overturning progressive waves, breaking standing waves and sloshing problems.
    Additional Material: 17 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/fld.1650150912
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  • 7
    Electronic Resource
    Electronic Resource
    Non-oscillatory shock-capturing finite element methods for the one-dimensional compressible Euler equations (1990)
    Chichester : Wiley-Blackwell
    International Journal for Numerical Methods in Fluids 11 (1990), S. 405-426 
    Details
    ISSN: 0271-2091
    Keywords: TVD ; TVB ; ENO ; Finite element ; Euler equations ; Engineering ; Engineering General
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Notes: A class of shock-capturing Petrov-Galerkin finite element methods that use high-order non-oscillatory interpolations is presented for the one-dimensional compressible Euler equations. Modified eigenvalues which employ total variation diminishing (TVD), total variation bounded (TVB) and essentially non-oscillatory (ENO) mechanisms are introduced into the weighting functions. A one-pass Euler explicit transient algorithm with lumped mass matrix is used to integrate the equations. Numerical experiments with Burgers' equation, the Riemann problem and the two-blast-wave interaction problem are presented. Results indicate that accurate solutions in smooth regions and sharp and non-oscillatory solutions at discontinuities are obtainable even for strong shocks.
    Additional Material: 16 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/fld.1650110405
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  • 8
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    Expression of interleukin-10 activity by Epstein-Barr virus protein BCRF1 (1990)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1990-11-09
    Description: Cytokine synthesis inhibitory factor (CSIF; interleukin-10), a product of mouse TH2 T cell clones that inhibits synthesis of cytokines by mouse TH1 T cell clones, exhibits extensive sequence similarity to an uncharacterized open reading frame in the Epstein-Barr virus BCRF1. Recombinant BCRF1 protein mimics the activity of interleukin-10, suggesting that BCRF1 may have a role in the interaction of the virus with the host's immune system.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Hsu, D H -- de Waal Malefyt, R -- Fiorentino, D F -- Dang, M N -- Vieira, P -- de Vries, J -- Spits, H -- Mosmann, T R -- Moore, K W -- New York, N.Y. -- Science. 1990 Nov 9;250(4982):830-2.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Department of Immunology, DNAX Research Institute, Palo Alto, CA 94304.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/2173142" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Cell Line ; DNA, Viral/genetics ; Electrophoresis, Polyacrylamide Gel ; *Gene Expression Regulation, Viral ; Herpesvirus 4, Human/genetics/*immunology ; Humans ; Interleukin-10 ; Interleukins/*biosynthesis ; Killer Cells, Natural/immunology ; Mice ; Radioimmunoprecipitation Assay ; T-Lymphocytes/immunology ; Viral Proteins/genetics/*immunology
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
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  • 9
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    An insulin-stimulated protein kinase similar to yeast kinases involved in cell cycle control (1990)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1990-07-06
    Description: A protein kinase characterized by its ability to phosphorylate microtubule-associated protein-2 (MAP2), is thought to be an early intermediate in an insulin-stimulated phosphorylation cascade and in a variety of other mammalian cell responses to extracellular signals. A complementary DNA that encodes this protein serine-threonine kinase has been cloned, and the protein designated extracellular signal-regulated kinase 1 (ERK1). ERK1 has striking similarity to two protein kinases, KSS1 and FUS3, from yeast. The yeast kinases function in an antagonistic manner to regulate the cell cycle in response to mating factors. Thus, ERK1 and the two yeast kinases constitute a family of evolutionarily conserved enzymes involved in regulating the response of eukaryotic cells to extracellular signals.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Boulton, T G -- Yancopoulos, G D -- Gregory, J S -- Slaughter, C -- Moomaw, C -- Hsu, J -- Cobb, M H -- DK 01918/DK/NIDDK NIH HHS/ -- DK 34128/DK/NIDDK NIH HHS/ -- New York, N.Y. -- Science. 1990 Jul 6;249(4964):64-7.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Department of Pharmacology, University of Texas Southwestern Graduate School of Biomedical Sciences, Dallas 75235.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/2164259" target="_blank"〉PubMed〈/a〉
    Keywords: Amino Acid Sequence ; Animals ; Base Sequence ; Calcium-Calmodulin-Dependent Protein Kinases ; Cell Cycle/*physiology ; Cell Line ; Central Nervous System/*enzymology ; DNA/*genetics ; Fibroblasts/enzymology ; Humans ; Insulin/pharmacology ; Mitogen-Activated Protein Kinase 3 ; *Mitogen-Activated Protein Kinases ; Molecular Sequence Data ; Phosphorylation ; Protein Kinases/genetics/*metabolism ; Rats ; Receptor, Insulin/metabolism ; Yeasts/enzymology
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
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  • 10
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    Three-dimensional structures of acidic and basic fibroblast growth factors (1991)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1991-01-04
    Description: Members of the fibroblast growth factor (FGF) family of proteins stimulate the proliferation and differentiation of a variety of cell types through receptor-mediated pathways. The three-dimensional structures of two members of this family, bovine acidic FGF and human basic FGF, have been crystallographically determined. These structures contain 12 antiparallel beta strands organized into a folding pattern with approximate threefold internal symmetry. Topologically equivalent folds have been previously observed for soybean trypsin inhibitor and interleukins-1 beta and -1 alpha. The locations of sequences implicated in receptor and heparin binding by FGF are presented. These sites include beta-sheet strand 10, which is adjacent to the site of an extended sequence insertion in several oncogene proteins of the FGF family, and which shows sequence conservation among the FGF family and interleukin-1 beta.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Zhu, X -- Komiya, H -- Chirino, A -- Faham, S -- Fox, G M -- Arakawa, T -- Hsu, B T -- Rees, D C -- New York, N.Y. -- Science. 1991 Jan 4;251(4989):90-3.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Division of Chemistry and Chemical Engineering, California Institute of Technology, Pasadena 91125.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/1702556" target="_blank"〉PubMed〈/a〉
    Keywords: Amino Acid Sequence ; Animals ; Cattle ; Chemistry, Physical ; Crystallization ; Fibroblast Growth Factor 1/*chemistry/metabolism ; Fibroblast Growth Factor 2/*chemistry/metabolism ; Heparin/metabolism ; Humans ; Interleukin-1/chemistry ; Molecular Sequence Data ; Molecular Structure ; Physicochemical Phenomena ; Protein Conformation ; Recombinant Proteins/chemistry ; Sequence Homology, Nucleic Acid ; X-Ray Diffraction
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
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