ISSN:
1040-0397
Keywords:
Pulsed electrochemical detection
;
Carbohydrates
;
Liquid chromatography
;
Chemistry
;
Polymer and Materials Science
Source:
Wiley InterScience Backfile Collection 1832-2000
Topics:
Chemistry and Pharmacology
Notes:
Waveforms used in pulsed electrochemical detection (PED) have frequencies of ca. 1 Hz when optimized to give a maximum signal-to-noise ratio (S/N) for carbohydrates. However, higher frequencies are desired for application of PED to capillary electrophoresis (CE) and microcolumn lipuid chromatography (MLC), which can produce narrow elution peaks. Minimization of the time periods for oxidative cleaning and reductive reactivation in PED waveforms generated by the Dionex pulsed Electrochemical Detector allows the increase in waveform frequency to ca. 3 Hz without change in the traditional time period of 200 ms, prescribed for integration of the anodic current. However, further increase in frequency requires a decrease in the integration period with a corresponding loss of signal strength.
Additional Material:
6 Ill.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1002/elan.1140060402
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