Publication Date:
1992-05-01
Description:
Sialylated oligosaccharides, which are cell type-specific and developmentally regulated, have been implicated in a variety of complex biological events. Their broad functional importance is reflected by their presence in a wide variety of phyla extending from Echinodermata through higher vertebrates. Here, sialic acids are detected throughout development in an insect, Drosophila. Homopolymers of alpha 2,8-linked sialic acid, polysialic acid, are developmentally regulated and only expressed during early Drosophila development.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Roth, J -- Kempf, A -- Reuter, G -- Schauer, R -- Gehring, W J -- New York, N.Y. -- Science. 1992 May 1;256(5057):673-5.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Department of Cell Biology, University of Basel, Switzerland.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/1585182" target="_blank"〉PubMed〈/a〉
Keywords:
Animals
;
Antibodies, Monoclonal
;
Blotting, Western
;
Cell Adhesion Molecules, Neuronal/analysis
;
Drosophila melanogaster/chemistry/*embryology
;
Gas Chromatography-Mass Spectrometry
;
Histocytochemistry
;
Immunoblotting
;
Mice
;
Sialic Acids/analysis/*metabolism
Print ISSN:
0036-8075
Electronic ISSN:
1095-9203
Topics:
Biology
,
Chemistry and Pharmacology
,
Computer Science
,
Medicine
,
Natural Sciences in General
,
Physics
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