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  • Springer  (74)
  • American Society of Hematology  (4)
  • 1990-1994  (78)
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Year
  • 1
    Electronic Resource
    Electronic Resource
    Springer
    The European physical journal 340 (1991), S. 109-110 
    ISSN: 1434-601X
    Source: Springer Online Journal Archives 1860-2000
    Topics: Physics
    Notes: Abstract The very neutron deficient nucleus 104Sn has been identified in in-beam spectroscopy using the reaction50Cr(58Ni, 2p2n) and neutron and charged particle multiplicity filter detectors. Excited states up to I ≈ 10 and Ex=4 MeV were observed and the level scheme is discussed in the frame work of the spherical shell model.
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Springer
    Archive for history of exact sciences 41 (1990), S. 1-40 
    ISSN: 1432-0657
    Source: Springer Online Journal Archives 1860-2000
    Topics: Mathematics , Natural Sciences in General
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    Springer
    Letters in mathematical physics 21 (1991), S. 139-149 
    ISSN: 1573-0530
    Keywords: 81C05
    Source: Springer Online Journal Archives 1860-2000
    Topics: Mathematics , Physics
    Notes: Abstract We consider atomic and molecular systems with fixed nuclei where the electrons are assumed to be bosons. Then the ionization energies are rigorously computable in the limit of large particle numbers.
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  • 4
    Electronic Resource
    Electronic Resource
    Springer
    Algorithmica 9 (1993), S. 313-328 
    ISSN: 1432-0541
    Keywords: Perfect powers ; Number theoretic algorithms ; Riemann hypothesis ; Newton's method ; Sieve algorithms ; Parallel algorithms ; Average-case analysis
    Source: Springer Online Journal Archives 1860-2000
    Topics: Computer Science , Mathematics
    Notes: Abstract A positive integern is a perfect power if there exist integersx andk, both at least 2, such thatn=x k . The usual algorithm to recognize perfect powers computes approximatekth roots fork≤log 2 n, and runs in time O(log3 n log log logn). First we improve this worst-case running time toO(log3 n) by using a modified Newton's method to compute approximatekth roots. Parallelizing this gives anNC 2 algorithm. Second, we present a sieve algorithm that avoidskth-root computations by seeing if the inputn is a perfectkth power modulo small primes. Ifn is chosen uniformly from a large enough interval, the average running time isO(log2 n). Third, we incorporate trial division to give a sieve algorithm with an average running time ofO(log2 n/log2 logn) and a median running time ofO(logn). The two sieve algorithms use a precomputed table of small primes. We give a heuristic argument and computational evidence that the largest prime needed in this table is (logn)1+O(1); assuming the Extended Riemann Hypothesis, primes up to (logn)2+O(1) suffice. The table can be computed in time roughly proportional to the largest prime it contains. We also present computational results indicating that our sieve algorithms perform extremely well in practice.
    Type of Medium: Electronic Resource
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  • 5
    Electronic Resource
    Electronic Resource
    Springer
    Environmental geology 24 (1994), S. 1-6 
    ISSN: 1432-0495
    Keywords: Nitrate ; Groundwater ; Modeling ; Denitrification ; Nitrogen balance
    Source: Springer Online Journal Archives 1860-2000
    Topics: Geosciences
    Notes: Abstract Implemented on behalf of the Federal Ministry for Research and Technology (BMFT), a model is developed to trace the nutrient flow of nitrate in the soil and the groundwater on a supraregional scale. Research work is intended to indicate regionally differentiated hazardous potentials and thereby provide a basis for recommending comprehensive measures to protect groundwater in Germany. The adaption of the model to the hydrogeological and agricultural conditions of other states is possible in principle. This article focuses on the hydrogeological model parts. A high nitrate pollution of groundwater can be expected in all regions with intensive agricultural use of the topsoil. In particular, groundwater in solid rock areas is susceptible to nitrate pollution. There a rapid groundwater turnover and thus a short residence time for the groundwater in the aquifer is typical. Oxidizing aquifer conditions usually prevail in solid rock aquifers, preventing nitrate degradation. In many loose rock areas, in contrast, the groundwater has a low flow velocity and a long residence time in the aquifer. Because of a lack of free oxygen, a complete degradation of nitrate can occur, as long as iron sulfide compounds and/or organic carbon are available in the aquifer. A more detailed presentation of the whole research work is given in Wendland et al. (1993).
    Type of Medium: Electronic Resource
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  • 6
    Electronic Resource
    Electronic Resource
    Springer
    Communications in mathematical physics 147 (1992), S. 527-548 
    ISSN: 1432-0916
    Source: Springer Online Journal Archives 1860-2000
    Topics: Mathematics , Physics
    Notes: Abstract We estimate the error of the Hartree-Fock energy of atoms and molecules in terms of the one-particle density matrix corresponding to the exact ground state. As an application we show this error to be of orderO(Z 5/3−δ) for any δ〈2/21 as the total nuclear chargeZ becomes large.
    Type of Medium: Electronic Resource
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  • 7
    Electronic Resource
    Electronic Resource
    Springer
    Human genetics 〈Berlin〉 86 (1991), S. 531-533 
    ISSN: 1432-1203
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary Among all the Jewish families with Hunter patients in Israel, 10 were Ashkenazi or Moroccan in origin. In those families, there was a paucity of new mutations. In addition, a significant deviation of the segregation ratio between the Hunter gene and the normal allele was demonstrated among the offspring of heterozygous mothers or siblings of affected children in these families. These results confirm and extend our previous observations suggesting selection in favor of the X chromosome carrying the Hunter allele among Ashkenazi and Moroccan Jews.
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  • 8
    ISSN: 1432-1211
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
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  • 9
    ISSN: 1432-1211
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Abstract We previously isolated a series of cDNA clones designated NKG2-A, B, C, and D from a human natural killer (NK) cell library. These transcripts encode a family of type II integral membrane proteins having an extracellular Ca2+-dependent lectin domain. The predicted peptides share structural similarities and amino acid sequence similarity with known receptor molecules. In this report, the genomic organization and mRNA expression of each of the genes were studied by using transcript-specific probes. Southern blot experiments reveal that the probes cross-hybridize with a maximum of five genes at high stringency. By probing a Southern blot prepared from a series of hamster/human hybrid somatic cell lines, we demonstrated that all of the hybridizing fragments occur on human chromosome 12. No gene rearrangement and little restriction fragment length polymorphism (RFLP) was observed with these probes. mRNA expression of the NKG2 genes occured in NK cells and some T cells but not in other hematopoietic cell types or in other tissues tested. Each of the transcripts occurred in all three of the NK cell lines tested: however, the genes were differentially regulated in T cells. NKG2-D was expressed in nine of fourteen T-cell clones or lines in the panel, whereas NKG2-A/B was expressed in three and NKG2-C was expressed in only one. Expression of each of the transcripts was upregulated following T-cell growth factor (TCGF)-induced activation of a cloned NK cell. The limited distribution of these proteins and their sequence similarity with known receptor molecules suggest that they may function as receptors of human NK cells.
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  • 10
    ISSN: 1432-1203
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary We have isolated cDNA clones from a human NK cell cDNA library that encode the serine protease granzyme B. Although the sequence of the entire coding region for the mature protein and the 3′ untranslated region of the clone are identical to other cDNA isolates of this gene obtained from human T cell cDNA libraries, the 5′ end of two clones is 103 bp longer than the previously described sequences and would encode a protein with a 54-amino-acid-long signal sequence. Experiments characterizing granzyme B mRNA suggest that transcripts that initiate at or before the 5′ end of these clones comprise a detectable but infrequent class of granzyme B transcripts in NK and T cells. We have mapped this gene to human chromosome 14 in the region 14q11→14q32, distal to the T cell receptor alpha locus and proximal to the immunoglobulin heavy chain locus. The chromosomal location of this gene, together with the previously described high sequence homology between this gene and the mouse CTLA1/ccp1 gene, make it likely that this is the human equivalent of the mouse CTLA 1/ ccp1.
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