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  • Springer  (12)
  • American Association for the Advancement of Science (AAAS)  (1)
  • 1990-1994  (13)
  • 1
    Publikationsdatum: 1993-07-02
    Beschreibung: The enhancer for the immunoglobulin mu heavy chain gene (IgH) activates a heterologous gene at the pre-B cell stage of B lymphocyte differentiation. A lymphoid-specific element, microB, is necessary for enhancer function in pre-B cells. A microB binding protein is encoded by the PU.1/Spi-1 proto-oncogene. Another sequence element, microA, was identified in the mu enhancer that binds the product of the ets-1 proto-oncogene. The microA motif was required for microB-dependent enhancer activity, which suggests that a minimal B cell-specific enhancer is composed of both the PU.1 and Ets-1 binding sites. Co-expression of both PU.1 and Ets-1 in nonlymphoid cells trans-activated reporter plasmids that contained the minimal mu enhancer. These results implicate two members of the Ets family in the activation of IgH gene expression.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Nelsen, B -- Tian, G -- Erman, B -- Gregoire, J -- Maki, R -- Graves, B -- Sen, R -- 1K04GM00563/GM/NIGMS NIH HHS/ -- GM38663/GM/NIGMS NIH HHS/ -- GM38925/GM/NIGMS NIH HHS/ -- New York, N.Y. -- Science. 1993 Jul 2;261(5117):82-6.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Rosenstiel Research Center, Brandeis University, Waltham, MA 02254.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/8316859" target="_blank"〉PubMed〈/a〉
    Schlagwort(e): Animals ; B-Lymphocytes/cytology/*metabolism ; Base Sequence ; Binding Sites ; Cell Differentiation ; Cell Line ; DNA-Binding Proteins/*genetics/metabolism ; *Enhancer Elements, Genetic ; Female ; Genes, Immunoglobulin ; Humans ; Immunoglobulin mu-Chains/*genetics ; Molecular Sequence Data ; Mutation ; Proto-Oncogene Protein c-ets-1 ; Proto-Oncogene Proteins/*genetics/metabolism ; Proto-Oncogene Proteins c-ets ; Retroviridae Proteins, Oncogenic ; Transcription Factors/*genetics/metabolism
    Print ISSN: 0036-8075
    Digitale ISSN: 1095-9203
    Thema: Biologie , Chemie und Pharmazie , Informatik , Medizin , Allgemeine Naturwissenschaft , Physik
    Standort Signatur Erwartet Verfügbarkeit
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  • 2
    Digitale Medien
    Digitale Medien
    Springer
    Mathematische Annalen 298 (1994), S. 761-764 
    ISSN: 1432-1807
    Schlagwort(e): 14J30 ; 32J17 ; 32J27
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Mathematik
    Materialart: Digitale Medien
    Standort Signatur Erwartet Verfügbarkeit
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  • 3
    Digitale Medien
    Digitale Medien
    Springer
    Inventiones mathematicae 101 (1990), S. 101-172 
    ISSN: 1432-1297
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Mathematik
    Materialart: Digitale Medien
    Standort Signatur Erwartet Verfügbarkeit
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  • 4
    Digitale Medien
    Digitale Medien
    Springer
    International journal of game theory 20 (1992), S. 247-254 
    ISSN: 1432-1270
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Mathematik , Wirtschaftswissenschaften
    Notizen: Abstract This paper deals with the existence of equilibrium in generalized games (the so-called abstract economies) and Nash equilibrium in games with general assumptions. Preference correspondences, unlike the existing theorems in the literature, need not have open graphs or open lower sections, strategy spaces need not be compact and finite dimensional, the number of agents need not be countable, and preference relations need not be ordered. Thus, our results generalize many of the existence theorems on equilibria in generalized games, including those of Debreu (1952), Shafer and Sonnenschein (1975), Toussaint (1984), Kim and Richter (1986), and Yannelis (1987).
    Materialart: Digitale Medien
    Standort Signatur Erwartet Verfügbarkeit
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  • 5
    Digitale Medien
    Digitale Medien
    Springer
    Molecular genetics and genomics 225 (1991), S. 340-341 
    ISSN: 1617-4623
    Schlagwort(e): Intron ; Group I ; DNA endonuclease ; Mitochondria ; Saccharomyces cerevisiae
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Biologie
    Notizen: Summary Two group I intron-encoded proteins from the yeast mitochondrial genome have already been shown to have a specific DNA endonuclease activity. This activity mediates intron insertion by cleaving the DNA sequence corresponding to the splice junction of an intronless strain. We have discovered in mitochondrial extracts from the yeast strain 777-3A a new DNA endonuclease activity which cleaves the fused exon A3-exon A4 junction sequence of the COXI gene.
    Materialart: Digitale Medien
    Standort Signatur Erwartet Verfügbarkeit
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  • 6
    Digitale Medien
    Digitale Medien
    Springer
    Plant and soil 153 (1993), S. 179-187 
    ISSN: 1573-5036
    Schlagwort(e): alfisols ; maize ; mulch quality ; nutrient uptake
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Land- und Forstwirtschaft, Gartenbau, Fischereiwirtschaft, Hauswirtschaft
    Notizen: Abstract Effects of application of prunings of three woody species (Acioa barteri, Gliricidia sepium and Leucaena leucocephala), maize (Zea mays L.) stover and rice (Oryza sativa L.) straw as mulch on maize were studied on an Alfisol in southern Nigeria in 1990 and 1991. Maize dry matter and grain yield were higher with applications of plant residues and N fertilizer in both years. Addition of Leucaena prunings gave the highest maize grain yield in both years. Compared to the 1990 results, Acioa showed the least grain yield decline among the mulch treatments in 1991. Nutrient uptake was enhanced by applications of plant residues. Leucaena prunings had the highest effect in both years and increased the mean N, P, and Mg uptake by 96%, 84%, and 50%, respectively, over the control. Addition of Acioa prunings increased K and Ca uptake by 59% and 92%, respectively, over the control. ‘High quality’ (low C/N ratio and lignin level) plant residues enhance crop performance through direct nutritional contributions, whereas ‘low quality’ (high C/N ratio and lignin level) plant residues do so through mulching effects on the microclimate. ‘Intermediate quality’ plant residues have no clear effects on crop performance.
    Materialart: Digitale Medien
    Standort Signatur Erwartet Verfügbarkeit
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  • 7
    ISSN: 1573-515X
    Schlagwort(e): agroforestry ; alley cropping ; leaf composition ; leaf mineralization ; calcium nitrogen and magnesium release ; woody and herbaceous species
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Chemie und Pharmazie , Geologie und Paläontologie
    Notizen: Abstract Nitrogen, Ca and Mg release from leaves of ten selected plant residues with varying chemical compositions was studied under laboratory conditions. Three patterns of N-release were observed over a seven week incubation period: (a)Gliricidia sepium, Leucaena leucocephala, Mucuna pruriens andCentrosema pubescens leaves showed rapid N release, (b)Acioa barteri andDialium guineense leaves immobilized N, and (c)Alchornea cordifolia, Anthonata macrophylla, Cassia siamea andPterocarpus santalinoides leaves initially showed N immobilization which gradually changes to net mineralization after about four weeks of incubation. Nitrogen mineralization rate constant (k) ranged from −0.0018 (A. barteri) to 0.0064 day−1 (G. sepium). Statistical analysis of data showed that N mineralization rate constants are significantly correlated with initial N, polyphenol and lignin contents of leaves. Nitrogen release increased with increasing N content and decreased with increasing contents of polyphenols and lignin. Addition of leaves from all species significantly increased soil exchangeable Ca and Mg levels.L. leucocephala, G. sepium, C. pubescens andM. pruriens showed relatively high Ca and Mg release rates. Calcium release rate was related to N release rate rather than to initial Ca content.
    Materialart: Digitale Medien
    Standort Signatur Erwartet Verfügbarkeit
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  • 8
    Digitale Medien
    Digitale Medien
    Springer
    Agroforestry systems 26 (1994), S. 249-254 
    ISSN: 1572-9680
    Schlagwort(e): phytotoxicity ; cowpea ; Gliricidia sepium prunings ; maize ; seedlings
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Land- und Forstwirtschaft, Gartenbau, Fischereiwirtschaft, Hauswirtschaft
    Notizen: Abstract Phytotoxic effects ofGliricidia prunings were tested on maize seedlings in the laboratory and on maize and cowpea seedlings in the field. In the laboratory test, growth of maize seedlings was significantly depressed by addition of leachate ofGliricidia prunings. In the field, leaf, chlorosis of maize and cowpea seedlings occurred when mulched withGliricidia prunings; number of affected leaves increased with increasing mulch rate. Maize was more susceptible than cowpea. This phytotoxic effect, however, did not reduce growth of maize and cowpea seedlings in the field. ApplyingGliricidia mulch one week before planting eliminated the phytotoxic effects on maize.
    Materialart: Digitale Medien
    Standort Signatur Erwartet Verfügbarkeit
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  • 9
    Digitale Medien
    Digitale Medien
    Springer
    Journal of optimization theory and applications 83 (1994), S. 375-389 
    ISSN: 1573-2878
    Schlagwort(e): KKM theorem ; variational inequalities ; complementarity problem ; price equilibrium ; maximal elements ; binary relations
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Mathematik
    Notizen: Abstract This paper extends the well-known KKM theorem and variational inequalities by relaxing the closedness of values of a correspondence and lower semicontinuity of a function. The approach adopted is based on Michael's continuous selection theorem. As applications, we provide theorems for the existence of maximum elements of a binary relation, a price equilibrium, and the complementarity problem. Thus our theorems, which do not require the openness of lower sections of the preference correspondences and the lower semicontinuity of the excess demand functions, generalize many of the existence theorems such as those in Sonnenschein (Ref. 1), Yannelis and Prabhakar (Ref. 2), and Border (Ref. 3).
    Materialart: Digitale Medien
    Standort Signatur Erwartet Verfügbarkeit
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  • 10
    Publikationsdatum: 1994-11-01
    Print ISSN: 0022-3239
    Digitale ISSN: 1573-2878
    Thema: Mathematik
    Publiziert von Springer
    Standort Signatur Erwartet Verfügbarkeit
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