ISSN:
1572-9729
Keywords:
chloroguaiacol
;
chlorocatechol
;
methoxylated aromatics
;
anaerobic O-demethylation
;
biotransformation
;
acetogen
Source:
Springer Online Journal Archives 1860-2000
Topics:
Biology
,
Energy, Environment Protection, Nuclear Power Engineering
,
Agriculture, Forestry, Horticulture, Fishery, Domestic Science, Nutrition
Notes:
Abstract The acetogenic bacteriaEubacterium limosum andAcetobacterium woodii are strict anaerobes with the ability to metabolizeO-methyl substituents of aromatic compounds. In investigating the versatility of the O-demethylating activity of these acetogens, we examined the anaerobic O-demethylation of chlorinated guaiacols (2-methoxyphenols). Anaerobic cell suspensions of bothE. limosum andA. woodii were able to O-demethylate di-, tri- and tetrachloroguaiacols to the corresponding catechols. The chlorocatechols accumulated and were not further metabolized. A chlorine substituent in the positionortho to the methoxyl-group hindered, but did not completely inhibit O-demethylation. Similar O-demethylation of chloroguaiacols has been observed in anaerobic sediments. The O-demethylating enzyme(s) of both strains seem to be fairly non-specific.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF00702327
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