ALBERT

All Library Books, journals and Electronic Records Telegrafenberg

feed icon rss

Your email was sent successfully. Check your inbox.

An error occurred while sending the email. Please try again.

Proceed reservation?

Export
Filter
  • ASTROPHYSICS  (5)
  • cardiomyocytes  (2)
  • 1990-1994  (7)
  • 1905-1909
  • 1
    Electronic Resource
    Electronic Resource
    Springer
    Molecular and cellular biochemistry 117 (1992), S. 63-70 
    ISSN: 1573-4919
    Keywords: glycogen phosphorylase ; alloxan-diabetes ; cardiomyocytes ; G-protein
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Chemistry and Pharmacology , Medicine
    Notes: Abstract The basis for the hypersensitive response of glycogen phosphorylase to epinephrine stimulation was investigated in adult rat cardiomyocytes isolated from normal and alloxan-diabetic animals. To assess potential G-protein involvement in the response, normal and diabetic derived myocytes were incubated with either cholera or pertussis toxin prior to hormonal stimulation. Pretreatment of cardiomyocytes with cholera toxin resulted in a potentiated response to epinephrine stimulation whereas pertussis toxin did not affect the activation of this signaling pathway. To determine if the enhanced response of phosphorylase activation resulted from an alteration in adenylate cyclase activation, the cells were challenged with forskolin. After 3 hr in primary culture, diabetic cardiomyocytes exhibited a hypersensitive response to forskolin stimulation relative to normal cells. However, after 24 hr in culture, both normal and diabetic myocytes responded identically to forskolin challenge. The present data suggest that a cholera toxin sensitive G-protein mediates the hypersensitive response of glycogen phosphorylase to catecholamine stimulation in diabetic cardiomyocytes and this response which is present in alloxan-diabetic cells and is induced in vitro in normal cardiomyocytes is primarily due to a defect at a post-receptor site.
    Type of Medium: Electronic Resource
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
  • 2
    ISSN: 1573-4919
    Keywords: cardiomyocytes ; SV40 large T antigen ; retroviral infection
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Chemistry and Pharmacology , Medicine
    Notes: Abstract Freshly isolated ventricular myocytes have been used extensively as an adult cardiac model system. Due to their inability to undergo cytokinesisin vitro and their dedifferentiated properties in long-term culture, they can not be used for extended studies. Recent reports tell of the establishment of fetal and neonatal cardiac cell lines and the development of adult cardiomyocytes from transgenic animals. A recent report by Kirshenbaum [1], is the first to demonstrate insertion of genes in to adult ventricular myocytes using viral infection. This paper discusses the infection of primary adult differentiated cardiomyocytes with the SV40 large T antigen and subsequent proliferation under temperature sensitive control. Upon further characterization, the cells could be used as a model to study muscle differentiation and repair as well as adult cardiac cell physiology.
    Type of Medium: Electronic Resource
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
  • 3
    Publication Date: 2019-07-12
    Description: Low-dispersion UV spectra taken by the IUE satellite of an S star HD 35155 are presented. It is shown that the spectra contain strong emission lines of multiply ionizes species and an excess continuous emission shortward of 2000 A. Because neither the photospheres nor chromospheres of S stars are expected to produce multiply ionized ions, the emission lines and the excess short-wave emission seen in the HD 35155 spectra are interpreted as an evidence of the presence of a hot nearby compact companion. Some inferences regarding the compact companion and the possible location of the source of the emission lines of multiply ionized ions are discussed.
    Keywords: ASTROPHYSICS
    Type: Astrophysical Journal, Part 1 (ISSN 0004-637X); 383; 842-852
    Format: text
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
  • 4
    Publication Date: 2019-07-13
    Description: We have obtained IUE spectra for 31 middle and late-type giant and supergiant stars whose TD-1 fluxes or ground-based spectra indicate the presence of a hot component, or whose radial velocities indicate an unseen component. Stellar components earlier than type F1 were detected in 22 cases. While 20 of the hot secondaries are seen weakly in optical spectra, two are UV discoveries: HD 58134 and HD 183864. The hot companions are classified accurately by temperature class from their far-UV spectra. The interstellar extinction of each system and the relative luminosities of the components are derived from the UV and optical fluxes, using a new grid of UV intrinsic colors for hot dwarfs. We find that many giant stars apparently have companions which are too hot and hence too luminous for consistency with the primary's spectral classification.
    Keywords: ASTROPHYSICS
    Type: Astrophysical Journal, Part 1 (ISSN 0004-637X); 412; 2; p. 814-826.
    Format: text
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
  • 5
    Publication Date: 2019-07-13
    Description: To test the popular hypothesis that technetium-deficient stars of spectral types S and MS are mass-transfer binaries, we have searched for ultraviolet light from the putative hot secondaries in spectra taken with the SWP spectrograph of IUE. Although most S and MS stars are apparently thermally pulsing AGB (asymptotic giant branch) stars whose surfaces have been enriched with s-process elements and carbon dredged up from the interior, those stars whose spectra show enhanced s-process elements but no Tc are widely believed to be cooler analogs of the Ba II stars, which apparently owe their unusual abundances to prior mass transfer, the Tc from which has decayed away. We report IUE observations of 15 S and MS stars with the SWP, including the identification of six hot companions. Assembling all the IUE observations made to date, we find clear support for the mass-transfer hypothesis, confirming evidence from other lines of research. We further discuss the ages of the companions and the implications of these discoveries for stellar evolution.
    Keywords: ASTROPHYSICS
    Type: Astrophysical Journal, Part 1 (ISSN 0004-637X); 402; 2; p. 667-679.
    Format: text
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
  • 6
    Publication Date: 2019-07-12
    Description: The K5 III star Alpha Tau was observed with the Goddard High Resolution Spectrograph on November 27, 1990 as part of the Science Assessment Program for the HST. The spectra show intersystem and permitted chromospheric emission lines of semiforbidden C II and Si II, Fe II, Fe I, Ni II, and Co II. Resolved profiles of the semiforbidden C II lines indicate a complex chromospheric turbulent velocity distribution with mean value of roughly 24 km/s, while their observed wavelengths indicate a 4 km/s downflow of the semiforbidden C II plasma. Twenty-five new emission lines have been found in the 2320-2370 A region, 17 of which have been identified with the aid of Skylab data obtained above the solar limb, including four lines from Co II (UV 8) and an Fe I (UV 12) line.
    Keywords: ASTROPHYSICS
    Type: Astrophysical Journal, Part 2 - Letters (ISSN 0004-637X); 377; L45-L48
    Format: text
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
  • 7
    Publication Date: 2019-07-12
    Description: IUE ultraviolet spectral observations reveal that the F supergiant HD 51956 contains a hot companion star partially obscured by warm plasma. Variable absorption features are analogous to those in the strongly interacting system HD 207739. The F type component is apparently transferring matter to a subluminous B type star which originally was the primary component.
    Keywords: ASTROPHYSICS
    Type: Astrophysical Journal, Part 2 - Letters (ISSN 0004-637X); 364; L13-L15
    Format: text
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
Close ⊗
This website uses cookies and the analysis tool Matomo. More information can be found here...