ALBERT

Description: The LITE electronics system consists of the following seven subsystems: Laser Transmitter Module (LTM), Boresight Assembly (BA), Aft-Optics Electronics (AOE), Digital Data Handling Unit (DDHU), Engineering Data System (EDS), Instrument Controller (IC), and the Ground Support Equipment (GSE). Each of these subsystems is discussed.

Description: Centrosomes are undetectable in unfertilized sea urchin eggs, and normally the sperm introduces the cell's microtubule-organizing center (MTOC) at fertilization. However, artificial activation or parthenogenesis triggers microtubule assembly in the unfertilized egg, and this study explores the reappearance and behavior of the maternal centrosome. During activation with A23187 or ammonia, microtubules appear first at the cortex; centrosomal antigen is detected diffusely throughout the entire cytoplasm. Later, the centrosome becomes more distinct and organizes a radial microtubule shell, and eventually a compact centrosome at the egg center organizes a monaster. In these activated eggs, centrosomes undergo cycles of compaction and decompaction in synchrony with the chromatin, which also undergoes cycles of condensation and decondensation. Parthenogenetic activation with heavy water (50% D2O) or the microtubule-stabilizing drug taxol (10 microM) induces numerous centrosomal foci in the unfertilized sea urchin egg. Within 15 min after incubation in D2O, numerous fine centrosomal foci are detected, and they organize a connected network of numerous asters which fill the entire egg. Taxol induces over 100 centrosomal foci by 15 min after treatment, which organize a corresponding number of asters. The centrosomal material in either D2O- or taxol-treated eggs aggregates with time to form fewer but denser foci, resulting in fewer and larger asters. Fertilization of eggs pretreated with either D2O or taxol shows that the paternal centrosome is dominant over the maternal centrosome. The centrosomal material gradually becomes associated with the enlarged sperm aster. These experiments demonstrate that maternal centrosomal material is present in the unfertilized egg, likely as dispersed undetectable material, which can be activated without paternal contributions. At fertilization, paternal centrosomes become dominant over the maternal centrosomal material.

Description: The authors reviewed the applications and limitations of computed tomography (CT) and magnetic resonance (MR) imaging in the assessment of the most common hip disorders. Magnetic resonance imaging is the most sensitive technique in detecting osteonecrosis of the femoral head. Magnetic resonance reflects the histologic changes associated with osteonecrosis very well, which may ultimately help to improve staging. Computed tomography can more accurately identify subchondral fractures than MR imaging and thus remains important for staging. In congenital dysplasia of the hip, the position of the nonossified femoral head in children less than six months of age can only be inferred by indirect signs on CT. Magnetic resonance imaging demonstrates the cartilaginous femoral head directly without ionizing radiation. Computed tomography remains the imaging modality of choice for evaluating fractures of the hip joint. In some patients, MR imaging demonstrates the fracture even when it is not apparent on radiography. In neoplasm, CT provides better assessment of calcification, ossification, and periosteal reaction than MR imaging. Magnetic resonance imaging, however, represents the most accurate imaging modality for evaluating intramedullary and soft-tissue extent of the tumor and identifying involvement of neurovascular bundles. Magnetic resonance imaging can also be used to monitor response to chemotherapy. In osteoarthrosis and rheumatoid arthritis of the hip, both CT and MR provide more detailed assessment of the severity of disease than conventional radiography because of their tomographic nature. Magnetic resonance imaging is unique in evaluating cartilage degeneration and loss, and in demonstrating soft-tissue alterations such as inflammatory synovial proliferation.

Description: No abstract available

Description: There are types of deafness and tinnitus in which ruptures or massive changes in the ionic permeability of the membranes lining the endolymphatic space [e.g., of the reticular lamina (RL)] are believed to allow potassium-rich endolymph to deluge the low [K+] perilymphatic fluid (e.g., in the small spaces of Nuel). This would result in a K+ intoxication of sensory and neural structures. Acute attacks of Meniere's disease have been suggested to be an important example for this event. The present study investigated the effects of transiently elevated [K+] due to the addition of artificial endolymph to the basolateral cell surface of outer hair cells (OHC) in replicating endolymph-induced K+ intoxication of the perilymph in the small spaces of Nuel. The influence of K+ intoxication of the basolateral OHC cell surface on the transduction was then examined. Intoxication resulted in an inhibition of the physiological repolarizing K+ efflux from hair cells. This induced unwanted depolarizations of the hair cells, interfering with mechanoelectrical transduction. A pathological longitudinal OHC shortening was also found, with subsequent compression of the organ of Corti possibly influencing the micromechanics of the mechanically active OHC. Both micromechanical and electrophysiological alterations are proposed to contribute to endolymph leakage induced attacks of deafness and possibly also to tinnitus. Moreover, repeated or long-lasting K+ intoxications of OHC resulted in a chronic and complete loss of OHC motility. This is suggested to be a pathophysiological basis in some patients with chronic hearing loss resulting from Meniere's syndrome.

Description: This manuscript outlines a continuing effort to validate and verify the performance of an airborne autonomous wavemeter for tuning solid state lasers to a desired wavelength. The application is measuring the vertical profiles of atmospheric water vapor using a differential absorption lidar (DIAL) technique. Improved wavemeter performance data for varying ambient temperatures are presented. This resulted when the electronic grounding and shielding were improved. The results with short pulse duration lasers are also included. These lasers show that similar performance could be obtained with lasers operating in the continuous and the pulsed domains.

Description: Results are presented on an automatic stereo analysis of cloud-top heights from nearly simultaneous satellite image pairs from the GOES and NOAA satellites, using a massively parallel processor computer. Comparisons of computer-derived height fields and manually analyzed fields show that the automatic analysis technique shows promise for performing routine stereo analysis in a real-time environment, providing a useful forecasting tool by augmenting observational data sets of severe thunderstorms and hurricanes. Simulations using synthetic stereo data show that it is possible to automatically resolve small-scale features such as 4000-m-diam clouds to about 1500 m in the vertical.

Description: An algorithm is presented for the construction of images using linear array data with nonuniform scan coverage of object space and nonuniform detector responses. The algorithm achieves the maximum correlation between adjacent pixels, i.e., the smoothest image, consistent with the data and data uncertainties. For high spatial data density and signal-to-noise ratio, the achievable spatial resolution can exceed the diffraction limit of the optics. The capability of the algorithm is illustrated using 60-micron data from the region centered on the galaxy M101, obtained during the all-sky survey performed by the Infrared Astronomical Satellite. The 60-micron map produced has a resolution of about 36 arcsec and allows the identification of many H II regions by position and aperture photometry for the brighter ones. The achieved resolution is discussed in terms of the a priori estimate of the mean correlation length of the data, the directly measured FWHM in the final image, and the results of aperture photometry of M101 H II regions NGC 5447, 5455, 5461, 5462 and 5471.

Description: Long-term column ozone density measurements have been carried out in Norway and USSR. Data from Tromso and two meridional chains in USSR are analyzed, and most of the stations show that no significant decreasing trend in ozone has occurred during the last two decades.

Description: The total ozone amount over Oslo has been measured with the Dobson spectrophotometer No 56. The instrument was modified, calibrated, and intercompared in 1977 in Boulder. A new intercomparison was made in 1986 in Arosa. Much work has been done to make the zenith charts reliable. A new method has been introduced where one takes into account the change in the shape of the zenith chart curves which is caused by a change of the ozone profile when the ozone amount changes. According to the conclusion derived from the intercomparison in Arosa 1986, the instrument has not been stable. The R-N tables had to be altered, but not the Q-tables. We have tried to account for this change in our handling of the observation data. No statistical analyses of these data has yet been made, but the monthly averages of the raw data show a negative linear trend of about 4 percent for the whole period.