ISSN:
1420-9071
Keywords:
Cisplatin
;
chlorpromazine
;
lethality
;
renal toxicity
;
mice
Source:
Springer Online Journal Archives 1860-2000
Topics:
Biology
,
Medicine
Notes:
Abstract The effect of chlorpromazine on acute lethal toxicity and nephrotoxicity induced by cisplatin was studied in mice. Chlorpromazine given (i.p.) 1 h before cisplatin greatly reduced lethal and renal toxicities of cisplatin. Chlorpromazine did not reduce the antitumor activity of cisplatin against Sarcoma 180 in ddY mice or EL-4 Leukemia in C57BL/6J mice.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF01948009
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