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  • Articles  (7)
  • Polymer and Materials Science  (4)
  • Animals  (3)
  • 550 - Earth sciences
  • Crystal Structure
  • 1990-1994  (6)
  • 1970-1974  (1)
  • Medicine  (7)
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  • Articles  (7)
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  • 1
    Electronic Resource
    Electronic Resource
    Histological and ultrastructural observations at the interface of expanded polytetrafluorethylene anterior cruciate ligament implants (1991)
    New York, NY [u.a.] : Wiley-Blackwell
    Journal of Applied Biomaterials 2 (1991), S. 29-35 
    Details
    ISSN: 1045-4861
    Keywords: Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Medicine , Technology
    Notes: Anteior cruciate ligament (ACL) grafts made from expanded polytetrafluorethylene (ePTFE) were examined after failure (n = 7; 3 instabilities, 2 partial and 2 complete ruptures) to provide information about secondary fixation mechanisms via ingrowth of the different tissues. The ultrastructural evaluation clearly evidenced the existence of two main interface areas of ePTFE ACL-replacement: First, in areas without a dense cellular infiltrate there was interdigitating collagen producing a dense ePTFE-collagen network. Additionally, in a few areas of the graft/bone-tunnel interface a fibrous cartilage or bone regenerate could be demonstrated to be in contact with the prosthesis. Second, there was a dense infiltration of macrophages and multinuclear giant cells, partially containing birefringent material of implant origin, with and without a neosynovia-like reaction product, indicating a disturbance of tissue integration of the prosthesis. In areas of inflammation there was no bone development and only few collagen interdigitation with the graft material. This study provides further knowledge about mechanisms of secondary graft fixation due to tissue ingrowth. The interdigitation of collagen fibers and ePTFE filaments provides interfaces which should be at least partially resistant against load.
    Additional Material: 8 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/jab.770020105
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  • 2
    Electronic Resource
    Electronic Resource
    Decreased tissue reaction to bioprosthetic heart valve material after L-glutamic acid treatment. A morphological study (1992)
    Hoboken, NJ : Wiley-Blackwell
    Journal of Biomedical Materials Research 26 (1992), S. 1231-1240 
    Details
    ISSN: 0021-9304
    Keywords: Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Medicine , Technology
    Notes: Degenerative alterations of two different glutaraldehyde (GA)-fixed bioprosthetic heart valve materials were investigated in subcutaneous rat implants: Bovine pericardium, prepared according to clinically used bioprosthetic heart valve material (BHV) was compared to alternatively preserved pericardium (APHV), which was fixed in GA and treated with L-glutamic acid. Following 63 days of subcutaneous implantation, calcification of APHV implants was significantly lower as compared to BHV implants (13 ± 6 versus 158 ± 18 μg Ca/mg dry weight tissue; p ± 0.05). In BHV implants ultrastructural investigations showed nucleation of plate-shaped hydroxyapatite crystals at the surface of collagen fibrils and in remnants of connective tissue cells; no signs of calcification could be detected in APHV implants. The time-course of the inflammatory reaction was determined by quantification of immunohistochemical stained mononuclear host-cells invading the implants. In both preparation groups inflammatory reaction reached maximum 42 days after implantation. However, infiltration rate of inflammatory cells was markedly decreased in APHVs as compared to BHVs (p ≤ 0.05). © 1992 John Wiley & Sons, Inc.
    Additional Material: 4 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/jbm.820260912
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  • 3
    Electronic Resource
    Electronic Resource
    The effect of glass-ceramic implants on matrix vesicle calcification after two weeks of rat tibial bone healingIn partial fulfillment of the requirements for a Ph.D. thesis by Dr. D. Amir performed in the Department of Pathology. (1990)
    Hoboken, NJ : Wiley-Blackwell
    Journal of Biomedical Materials Research 24 (1990), S. 1571-1584 
    Details
    ISSN: 0021-9304
    Keywords: Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Medicine , Technology
    Notes: Type, size and distribution of extracellular matrix vesicles (MV), known mediators of primary calcification, were studied around bone-bonding and metal-oxide containing, nonbonding, glass-ceramic implants. This was performed in order to further understand the different effects of implants on bone healing. At 14 days after implantation in adult rat tibial bone the effects of different implants on MV were studied by transmission electron microscopy and computerized morphometry. A total number of 4607 MV in 245 electron micrographs were counted and grouped according to diameter, distance from the calcifying front, and classified as four types: “empty,” “amorphous,” “crystal,” and “rupture.” The sequence of types according to diameter and distance was recorded as follows around both implants tested: “rupture” MV were the closest to the front with the largest diameter, followed by “crystal,” “amorphous,” and “empty,” MV with the largest distance from the front and the smallest diameter. Most vesicles were concentrated in a distance of less than 2.4 μm from the front and between diameters of 0.06 μm and 0.22 μm. The noncalcified extracellular matrix around bone-bonding implants contained more MV than the matrix around the nonbonding type (26.24 MV/10 μm2 and 18.76 MV/10μm2). MV distribution according to type showed that around bonding implants ther was a higher percentage of “crystal” and a lower percent age of “rupture” when compared to the nonbonding type. These results indicate that bonding implansts affect osteoblastic function by increasing tht vesicular number and retardation of intravesicular crystal fromation. It might be suggested that bonding implants induce an increase in the process of primary calcification and a decreased rate of crystal formation resulting with the highest organization of the healing bone.
    Additional Material: 9 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/jbm.820241203
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  • 4
    Electronic Resource
    Electronic Resource
    Polarization studies of surgical materials in ringer's solution (1970)
    Hoboken, NJ : Wiley-Blackwell
    Journal of Biomedical Materials Research 4 (1970), S. 29-41 
    Details
    ISSN: 0021-9304
    Keywords: Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Medicine , Technology
    Notes: The corrosion resistance of materials employed for surgical applications was dertermined and compared by means of potentiostatic anodic polarization techniques. In a physiological saline solution the passive breakdown potential of stainless steel materials was dependent upon the oxygen content opf the solution, and the microstructure of the material. The breakdown is passivity was found to be due to a pitting type of corrosion attack. Pure titanium remained passive within the limits employed in this investigation. Even though cast vitallium did not exhibit passivity breakdown in the form of a pitting attack, polarization behavior between the behavior for stainless stell and pure titanium was observed.
    Additional Material: 13 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/jbm.820040105
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  • 5
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    Density-dependent natural selection and trade-offs in life history traits (1991)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1991-07-26
    Description: Theories of density-dependent natural selection state that at extreme population densities evolution produces alternative life histories due to trade-offs. The trade-offs are presumed to arise because those genotypes with highest fitness at high population densities will not also have high fitness at low density and vice-versa. These predictions were tested by taking samples from six populations of Drosophila melanogaster kept at low population densities (r-populations) for nearly 200 generations and placing them in crowded cultures (K-populations). After 25 generations in the crowded cultures, the derived K-populations showed growth rate and productivity that at high densities were elevated relative to the controls, but at low density were depressed.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Mueller, L D -- Guo, P Z -- Ayala, F J -- S07 RR07008/RR/NCRR NIH HHS/ -- New York, N.Y. -- Science. 1991 Jul 26;253(5018):433-5.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Department of Ecology and Evolutionary Biology, University of California, Irvine 92717.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/1907401" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; *Biological Evolution ; Crosses, Genetic ; Drosophila melanogaster/*genetics/growth & development/physiology ; Ecology ; Female ; Genetic Variation ; Male ; Models, Genetic ; Population Growth ; *Selection, Genetic
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
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  • 6
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    Fruit fly aging and mortality (1993)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1993-06-11
    Description: 〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Nusbaum, T J -- Graves, J L -- Mueller, L D -- Rose, M R -- New York, N.Y. -- Science. 1993 Jun 11;260(5114):1567; author reply 1567-9.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/8503001" target="_blank"〉PubMed〈/a〉
    Keywords: Aging/physiology ; Animals ; Diptera/*physiology ; Drosophila melanogaster/*physiology ; Models, Biological ; Mortality ; Population Density
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
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  • 7
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    A high-temperature superconducting receiver for nuclear magnetic resonance microscopy (1993)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1993-02-05
    Description: A high-temperature superconducting-receiver system for use in nuclear magnetic resonance (NMR) microscopy is described. The scaling behavior of sources of sample and receiver-coil noise is analyzed, and it is demonstrated that Johnson, or thermal, noise in the receiver coil is the factor that limits resolution. The behavior of superconductors in the environment of an NMR experiment is examined, and a prototypical system for imaging biological specimens is discussed. Preliminary spin-echo images are shown, and the ultimate limits of the signal-to-noise ratio of the probe are investigated.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Black, R D -- Early, T A -- Roemer, P B -- Mueller, O M -- Mogro-Campero, A -- Turner, L G -- Johnson, G A -- 1P41 RR05959/RR/NCRR NIH HHS/ -- ES0 4187/ES/NIEHS NIH HHS/ -- New York, N.Y. -- Science. 1993 Feb 5;259(5096):793-5.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉General Electric Corporate Research and Development Center, Schenectady, NY 12301.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/8430331" target="_blank"〉PubMed〈/a〉
    Keywords: Animals ; Humans ; Magnetic Resonance Spectroscopy/*instrumentation/methods ; Models, Theoretical
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
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