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  • Springer  (21)
  • Wiley-Blackwell  (5)
  • Springer Nature  (3)
  • Wiley  (3)
  • Blackwell Publishing Ltd  (2)
  • Heidelberg: Springer
  • 1990-1994  (16)
  • 1970-1974  (18)
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  • 1
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Publishing Ltd
    Annals of the New York Academy of Sciences 675 (1992), S. 0 
    ISSN: 1749-6632
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Natural Sciences in General
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Publishing Ltd
    Physiologia plantarum 90 (1994), S. 0 
    ISSN: 1399-3054
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Biology
    Notes: The specific activities of 6 enzymes, which are involved in the synthesis and catabolism of membrane lipids, were monitored in plasma membranes isolated from petunia petals during senescence. These included phosphatidylinositol (PI) kinase (EC 2.7.1.67), phosphatidylinositol monophosphate (PIP) kinase (EC 2.7.1.68). diacylglycerol (DAG) kinase (EC 2.7.1.107), phospholipase A (EC 3.1.1.4) and PIP- and PIP2-phospholipase C˙(EC 3.1.4.3). Using endogenous substrate, the [32P]PA and [32P]PIP2 formation increased to 140 and 200%, respectively, of the day 1 value by 4 days after harvest. There was no significant change in [32P]PIP formation during the same time period. On the fifth day the petals wilted and the [32P]PA and [32P]PIP formation declined significantly. In contrast, the [32P]PIP2 formation remained high in the day 5 petals. When the lipid kinase activities were assayed in the membranes in the presence of exogenous substrate the specific activity of all of the enzymes increased. and the changes in [32P]PA production over the 5-day period were similar to those observed with endogenous substrate. When exogenous PI and PIP were added, however, there was no longer an increase in [32P]PIP2 formation by plasma membranes of day 4 petals and [32P]PIP formation significantly decreased. The relative decrease in PIP and PIP2 formation by day 4 membranes when exogenous substrate was added may have resulted from differences in the lipase activities in the day 1 and day 4 membranes. The plasma membrane A-type phospholipase activity increased throughout the 5 day period, and phospholipase C activity increased two-fold between day 1 and day 4. Such changes in the metabolism of the plasma membrane lipids during flower senescence would affect the ability of the petals to use inositol phospholipid-based signal transduction pathways.
    Type of Medium: Electronic Resource
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  • 3
    ISSN: 1420-9071
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Zusammenfassung Durch den Ausführungsgang der Ohrspeicheldrüse wurde Antiserum gegen Rattenblutserum eingeleitet, was zu einer schweren allergischen Entzündung der Parotisdrüse führte. Es wird angenommen, dass es sich bei dieser Entzündung um eine besondere Art von Arthusreaktion handelt.
    Type of Medium: Electronic Resource
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  • 4
    Electronic Resource
    Electronic Resource
    Springer
    Cellular and molecular life sciences 28 (1972), S. 483-484 
    ISSN: 1420-9071
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Résumé Dans les cultures de cellules du triton, les ponts interchromosomaux peuvent se former dans les figures métaphasiques sous l'influence d'une solution hypotonique. Ce résultat, obtenu au microscope à la lumière ordinaire, pose la question de savoir si les ponts déjà décrits dans les micrographes électroniques sont également dus à l'emploi des solutions hypotoniques.
    Type of Medium: Electronic Resource
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  • 5
    Electronic Resource
    Electronic Resource
    Springer
    Cellular and molecular life sciences 26 (1970), S. 374-376 
    ISSN: 1420-9071
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Résumé Chez les rats adrénalectomisés, une différence très nette de l'indice de la granularité juxtaglomérulaire est apparue entre les animaux qui avaient bu du 2% NaCl et ceux qui avaient reçu ou de l'eau distillée ou du 2% KCl. Il y a donc une réactivité juxtaglomérulaire, indépendente du cortex surrénal.
    Type of Medium: Electronic Resource
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  • 6
    Electronic Resource
    Electronic Resource
    Springer
    Computers and the humanities 27 (1993), S. 55-71 
    ISSN: 1572-8412
    Source: Springer Online Journal Archives 1860-2000
    Topics: Computer Science , Media Resources and Communication Sciences, Journalism
    Type of Medium: Electronic Resource
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  • 7
    Electronic Resource
    Electronic Resource
    Springer
    Computers and the humanities 27 (1993), S. 261-275 
    ISSN: 1572-8412
    Keywords: conceptual analysis ; knowledge representation ; knowledge engineering ; semantic networks ; text analysis
    Source: Springer Online Journal Archives 1860-2000
    Topics: Computer Science , Media Resources and Communication Sciences, Journalism
    Notes: Abstract This article addresses the methodological problem of the non-linear representation of philosophical systems in a computerized knowledge base. It is a problem of knowledge representation as defined in the field of artificial intelligence. Instead of a purely theoretical discussion of the issue, we present selected results of a practical experiment which has in itself some theoretical significance. We show how one can represent different philosophies using CODE, a knowledge engineering system developed by artificial intelligence researchers. The hypothesis is that such a computer based representation of philosophical systems can give insight into their conceptual structure. We argue that computer aided text analysis can apply knowledge representation tools and techniques developed in artificial intelligence and we estimate how philosophers as well as knowledge engineers could gain from this cross-fertilization. This paper should be considered as an experiment report on the use of knowledge representation techniques in computer aided text analysis. It is part of a much broader project on the representation of conceptual structures in an expert system. However, we intentionally avoided technical issues related to either Computer Science or History of Philosophy to focus on the benefit to enhance traditional humanistic studies with tools and methods developed in AI on the one hand and the need to develop more appropriate tools on the other.
    Type of Medium: Electronic Resource
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  • 8
    Electronic Resource
    Electronic Resource
    Springer
    Cellular and molecular life sciences 30 (1974), S. 551-552 
    ISSN: 1420-9071
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Zusammenfassung Nachweis von α-M-Fetoprotein im Harn trächtiger Ratten, die an Masugi-Nephritis litten. Da dieses hochmolekulare Eiweiss im Harn normaler trächtiger Tiere nicht vorkommt, beweist sein Auftreten bei den Nephritis-Ratten eine nicht selektive Proteinurie.
    Type of Medium: Electronic Resource
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  • 9
    ISSN: 1432-1904
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Chemistry and Pharmacology , Natural Sciences in General
    Type of Medium: Electronic Resource
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  • 10
    Electronic Resource
    Electronic Resource
    Springer
    Fresenius' Zeitschrift für analytische Chemie 252 (1970), S. 284-287 
    ISSN: 1618-2650
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology
    Description / Table of Contents: Zusammenfassung Durch täglich frische Zubereitung eines stabilen Fluorescenzreagenses, durch Fluorimetrie 80 min nach Zugabe des Fluorescenzreagenses zum dichlormethanextrahierten Cortisol, durch streng blasenfreie Füllung einer Spezialmikroküvette mittels Pumpvorrichtung und durch optimale Messung der Cortisolfluorescenz im registrierenden Spektralfluorimeter bei 464 nm (Anregung) und 522 nm (Emission) wurde die fluorimetrische Serumcortisolbestimmung verbessert. Die Methode erlaubt eine Serumcortisolbestimmung mit hoher Empfindlichkeit (〈 1 μg/100 ml), Präzision an einem Tag (Variationskoeffizient = 4,7% für 10 μg/ 100 ml) und Präzision von Tag zu Tag (VK=6–7%, Kontrollserum). Für die Spezifität der Methode sprechen die niedrigen Serumcortisolwerte von Adrenalektomierten unter Dexamethasonsubstitution (〈 2 μg/100 ml). Die klinische Brauchbarkeit der Methode für diagnostische und therapeutische Fragen wird diskutiert.
    Notes: Abstract The fluorometric determination of cortisol in serum was improved by the following measures: 1. Daily preparation of the fluorescence reagent (ethanol abs.: conc. H2SO4= 3∶7, v/v) at 0°C. 2. Fluorometry 80 min after the addition of the fluorescence reagent to dichloromethane extracted cortisol. 3. Filling of a special micro-cuvette by a pump system avoiding bubble formation in the cuvette. 4. Spectrofluorometer with optimal absorption (464 nm) and emission (522 nm) for cortisol. The method is of satisfactory sensitivity for cortisol (〈 1 μg/100 ml), precision (10 μg/100 ml ∶ S.D. = 0.5 μg/ 100 ml) and reproducibility from day to day (variation coefficient = 6–7%). The specificity of the method is demonstrated by the low values (〈 2 μg/100 ml) of total-adrenalectomized patients under dexamethasone maintainance (2 × 0.25 mg/day). The normal range (mean ± 2 S.D., logarithmic distribution) of 900 a.m. serum cortisol values of control persons is 9.7–32.0 μg/100 ml. Examples of the application of the method for diagnostic and therapeutic questions are reported.
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