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  • Springer  (4)
  • American Society of Hematology
  • Molecular Diversity Preservation International
  • 1990-1994  (2)
  • 1970-1974  (2)
  • 1
    Electronic Resource
    Electronic Resource
    A stress boundary value problem for an ideal fibre-reinforced rectangular beam with a longitudinal notch (1974)
    Springer
    Zeitschrift für angewandte Mathematik und Physik 25 (1974), S. 553-563 
    Details
    ISSN: 1420-9039
    Source: Springer Online Journal Archives 1860-2000
    Topics: Mathematics , Physics
    Description / Table of Contents: Zusammenfassung Das im Titel angezeigte Problem wird erörtert anhand eines idealen faserverstärkten rechteckigen Balkens mit einer symmetrsichen Längskerbe bei gleichmäßiger Spannung. Unter Verwendung der idealen Theorie stellt es sich heraus, daß die Verschiebungs- und Druckfelder von einem einzigen Integral abhängig sind, das für die Fälle, einer V-förmigen Kerbe und eines Linienrisses leicht zu berechnen ist. Voraussichtlich liefern diese Lösungen nützliche Annäherungen an die entsprechenden Ergebnisse bei ähnlich hoch anisotropischen Komponenten. Einfache Bruchkriterien werden verwendet, um die möglichen Arten des Versagens dieser Komponenten vorauszusagen.
    Notes: Summary The title problem is examined for a cross-section of an ideal fibre-reinforced rectangular beam with a symmetrical longitudinal notch, undergoing uniform tension. Using the ideal theory the displacement and stress fields are found to depend upon a single integral, which can be evaluated easily for the cases of a V-shaped notch and a line crack. It is anticipated that these solutions will be useful approximations to the corresponding results for similar highly anisotropic components. Simple fracture criteria are used to predict the possible modes of failure of these components.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01596118
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    Paper (German National Licenses)
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  • 2
    Electronic Resource
    Electronic Resource
    Numerical modeling of ventricular filling (1992)
    Springer
    Annals of biomedical engineering 20 (1992), S. 19-39 
    Details
    ISSN: 1573-9686
    Keywords: Diastole ; Diastolic function ; Echocardiography ; Doppler ; Mitral valve ; Relaxation ; Compliance ; Mathematical modeling
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine , Technology
    Notes: Abstract The fluid dynamical and physiological assumptions underlying general mathematical modeling of ventricular filling are outlined. We then describe the use of a lumped parameter model and computer simulation to study how the early transmitral velocity profile is affected by isolated changes in ventricular compliance and relaxation, atrial pressure and compliance, and valvular morphology. We show that the transmitral velocity is fundamentally affected by twophysical determinants: the transmitral pressure difference and the net compliance of the atrium and the ventricle. These physical determinants in turn are specified by the variousphysiologic parameters of interest. This approach has shown that peak velocity is most strongly affected by initial left atrial pressure, lowered somewhat by prolonged relaxation, low atrial and ventricular compliance, and systolic dysfunction. Peak acceleration is directly affected by atrial pressure and inversely affected by the time constant of isovolumic relaxation, with little influence of compliance, whereas the deceleration rate is almost purely given by mitral valve area divided by instantaneous atrioventricular compliance at the end of the rapid filling wave.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02368504
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  • 3
    Electronic Resource
    Electronic Resource
    Intestinal Water and Solute Absorption Studies: Comparison of in Situ Perfusion with Chronic Isolated Loops in Rats (1992)
    Springer
    Pharmaceutical research 9 (1992), S. 894-900 
    Details
    ISSN: 1573-904X
    Keywords: intestinal drug and water absorption ; intestinal perfusion ; glucose ; acetaminophen ; phenytoin
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology
    Notes: Abstract The effects of lumenal glucose on jejunal water transport and the influence of glucose-induced water absorption on solute uptake from single-pass perfusions are compared in anesthetized rats in situ and isolated chronic loops in unanesthetized rats in vivo. While the magnitudes of solute membrane permeabilities are consistently higher in the chronic loop system, the effects on water transport and its promotion of jejunal solute uptake are comparable between the two experimental systems. The effect of glucose-induced water absorption on the enhanced/baseline jejunal uptake ratio of the hydrophilic drug, acetaminophen, is greater than that for the lipophilic drug, phenytoin, in both experimental systems. The fact that chronic loop effective solute permeabilities were equivalent to solute membrane permeabilities in situ is consistent with greater lumenal fluid mixing in vivo. In addition, in situ body temperature affects the uptake of phenytoin but not acetaminophen, water, or glucose. This suggests that active and paracellular solute transport is not compromised in situ, while membrane partitioning and diffusion of lipophilic species are more sensitive to experimental conditions.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1023/A:1015848815616
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  • 4
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    A stress boundary value problem for an ideal fibre-reinforced rectangular beam with a longitudinal notch (1974)
    Springer
    Details
    Publication Date: 1974-09-01
    Print ISSN: 0044-2275
    Electronic ISSN: 1420-9039
    Topics: Mathematics , Physics
    Published by Springer
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