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  • Articles  (39)
  • 1990-1994  (24)
  • 1970-1974  (7)
  • 1955-1959  (5)
  • 1940-1944  (3)
  • Geosciences  (13)
  • Medicine  (12)
  • Mathematics  (11)
  • Computer Science  (4)
  • Technology  (4)
  • Economics  (1)
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  • Articles  (39)
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  • 1
    Electronic Resource
    Electronic Resource
    Characterization of broadly pleiotropic phenotypes caused by an hfq insertion mutation in Escherichia coli K-12 (1994)
    Oxford, UK : Blackwell Publishing Ltd
    Molecular microbiology 13 (1994), S. 0 
    Details
    ISSN: 1365-2958
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Biology , Medicine
    Notes: The region immediately downstream from the miaA tRNA modification gene at 94.8 min contains the hfq gene and the hflA region, which are important in the bacteriophage Qβ and lambda life cycles. The roles of these genes in bacteria remain largely unknown. We report here the characterization of two chromosomal hfq insertion mutations. An omega (ω) cassette insertion near the end of hfq resulted in phenotypes only slightly different from the parent, although transcript mapping demonstrated that the insertion was completely polar on hfq expression. In contrast, an equally polar omega cassette insertion near the beginning of hfq caused pronounced pleiotropic phenotypes, including decreased growth rates and yields, decreased negative supercoiling of piasmids in stationary phase, increased cell size, osmosensitivity, increased oxidation of carbon sources, increased sensitivity to ultraviolet light, and suppression of bgl activation by hns mutations, hfq::ω mutant phenotypes were distinct from those caused by omega insertions early in the miaA tRNA modification gene. On the other hand, both hfq insertions interfered with lambda phage plaque formation, probably by means of polarity at the hflA region. Together, these results show that hfq function plays a fundamental role in Escherichia coli physiology and that hfq and the hflA region are in the amiB-mutL-miaA-hfq-hflX superoperon.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1365-2958.1994.tb00400.x
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  • 2
    Electronic Resource
    Electronic Resource
    The mutL repair gene of Escherichia coli K-12 forms a superoperon with a gene encoding a new cell-wall amidase (1994)
    Oxford, UK : Blackwell Publishing Ltd
    Molecular microbiology 11 (1994), S. 0 
    Details
    ISSN: 1365-2958
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Biology , Medicine
    Notes: We report a molecular genetic analysis of the region Immediately upstream from the Escherichia coli mutL DNA repair gene at 94.8 min. An open reading frame ending 9bp upstream from the start of mutL corresponds to a 48kDa polypeptide detected previously in minicells. The predicted amino acid sequence of this 48kDa polypeptide shows homology to the major N-acetylmuramoyl-L-alanine amidase autolysin of Bacillus subtilis, a known amidase of Bacillus licheniformis, and the product of a Salmonella typhimurium gene that maps near SO min. Insertions in this upstream gene, which we named AmiB, or in mutL did not affect cell shape or viability; however, overexpression of the AmiB potypeptide caused ceil lysis, hypersensitivity to osmotic shock and treatment with water, and temporary autolysis by low levels of antibiotics, which are all consistent with AmiB acting as a cell-wall hydrolase. Analysis of chromosomal transcription demonstrated that amiB forms a complex operon with mutL and two additional upstream genes. mutL transcripts also originated from an internal promoter, designated PmutL, located in amiB 312bp upstream from the translational start of mutL. Together, these results suggest that E. coli contains a second amidase possibly involved in cell-wall hydrolysis, septation, or recycling, and that transcription of this amidase is directly linked to a gene central for DNA repair.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1365-2958.1994.tb00300.x
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  • 3
    Electronic Resource
    Electronic Resource
    The American Miniature Nuclear Generator, Snap III (1959)
    [s.l.] : Nature Publishing Group
    Nature 183 (1959), S. 643-644 
    Details
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] Snap III, standing for System for Nuclear ^j Auxiliary Power, is a miniature device capable of powering the telemetering apparatus in a space rocket. Its source of power comes from the decay energy generated by a source of radioactive polonium-210. The energy is converted directly to electric ...
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1038/183643a0
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  • 4
    Electronic Resource
    Electronic Resource
    ‘Ring Angels’ over South-East England (1959)
    [s.l.] : Nature Publishing Group
    Nature 183 (1959), S. 1759-1760 
    Details
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] Fig. 1. Hing angel of February 17, 1959 In the course of the present work we have observed sixteen such incidents, and the geographical distribution of the active centres is shown on Fig. 2. The ring angels tend to occur around certain active regions which have been marked upon the map as small ...
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1038/1831759a0
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  • 5
    Electronic Resource
    Electronic Resource
    Adaptive Rules for Seminonparametric Estimators That Achieve Asymptotic Normality (1991)
    New York : Cambridge University Press
    Econometric theory 7 (1991), S. 307-340 
    Details
    ISSN: 0266-4666
    Source: Cambridge Journals Digital Archives
    Topics: Economics
    Notes: In econometrics, seminonparametric (SNP) estimators originated in the consumer demand literature. The Fourier flexible form is a well-known example. The idea is to replace the consumer's indirect utility function with a truncated series expansion and then use a parametric procedure, such as nonlinear multivariate regression, to set a confidence interval on an elasticity. More recently, SNP estimators have been used in nonlinear time series analysis. A truncated Hermite expansion with an ARCH leading term is used as the conditional density of the process. The method of maximum likelihood is used to fit it to data.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1017/S0266466600004497
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  • 6
    Electronic Resource
    Electronic Resource
    Metaphysical derivations of a law of refraction: Damianos and grosseteste (1970)
    Springer
    Archive for history of exact sciences 6 (1970), S. 224-236 
    Details
    ISSN: 1432-0657
    Source: Springer Online Journal Archives 1860-2000
    Topics: Mathematics , Natural Sciences in General
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00327236
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  • 7
    Electronic Resource
    Electronic Resource
    Riemann surfaces, Clifford algebras and infinite dimensional groups (1990)
    Springer
    Communications in mathematical physics 130 (1990), S. 217-236 
    Details
    ISSN: 1432-0916
    Source: Springer Online Journal Archives 1860-2000
    Topics: Mathematics , Physics
    Notes: Abstract We introduce a class of Riemann surfaces which possess a fixed point free involution and line bundles over these surfaces with which we can associate an infinite dimensional Clifford algebra. Acting by automorphisms of this algebra is a “gauge” group of meromorphic functions on the Riemann surface. There is a natural Fock representation of the Clifford algebra and an associated projective representation of this group of meromorphic functions in close analogy with the construction of the basic representation of Kac-Moody algebras via a Fock representation of the Fermion algebra. In the genus one case we find a form of vertex operator construction which allows us to prove a version of the Boson-Fermion correspondence. These results are motivated by the analysis of soliton solutions of the Landau-Lifshitz equation and are rather distinct from recent developments in quantum field theory on Riemann surfaces.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02473351
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  • 8
    Electronic Resource
    Electronic Resource
    Endomorphism valued cohomology and gauge-neutral matter (1990)
    Springer
    Communications in mathematical physics 132 (1990), S. 383-413 
    Details
    ISSN: 1432-0916
    Source: Springer Online Journal Archives 1860-2000
    Topics: Mathematics , Physics
    Notes: Abstract For several physically interesting Calabi-Yau manifolds, we count and parametrize gauge-neutral matter particles occurring in corresponding superstring compactifications. To this end, we use the technique of exact and spectral sequences and then describe and discuss our results in the more familiar tensor notation.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02096655
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  • 9
    Electronic Resource
    Electronic Resource
    Riemann surfaces, Clifford algebras and infinite dimensional groups (1991)
    Springer
    Communications in mathematical physics 139 (1991), S. 217-236 
    Details
    ISSN: 1432-0916
    Source: Springer Online Journal Archives 1860-2000
    Topics: Mathematics , Physics
    Notes: Abstract We introduce a class of Riemann surfaces which possess a fixed point free involution and line bundles over these surfaces with which we can associate an infinite dimensional Clifford algebra. Acting by automorphisms of this algebra is a “gauge” group of meromorphic functions on the Riemann surface. There is a natural Fock representation of the Clifford algebra and an associated projective representation of this group of meromorphic functions in close analogy with the construction of the basic representation of Kac-Moody algebras via a Fock representation of the Fermion algebra. In the genus one case we find a form of vertex operator construction which allows us to prove a version of the Boson-Fermion correspondence. These results are motivated by the analysis of soliton solutions of the Landau-Lifshitz equation and are rather distinct from recent developments in quantum field theory on Riemann surfaces.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02102954
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  • 10
    Electronic Resource
    Electronic Resource
    Conformally invariant differential operators on Minkowski space and their curved analogues (1992)
    Springer
    Communications in mathematical physics 144 (1992), S. 213-213 
    Details
    ISSN: 1432-0916
    Source: Springer Online Journal Archives 1860-2000
    Topics: Mathematics , Physics
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02099197
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