ALBERT

All Library Books, journals and Electronic Records Telegrafenberg

feed icon rss

Your email was sent successfully. Check your inbox.

An error occurred while sending the email. Please try again.

Proceed reservation?

Export
Filter
  • Chemistry  (19)
  • Amino Acid Sequence  (6)
  • Molecular Sequence Data  (5)
  • Inorganic Chemistry
  • 1990-1994  (16)
  • 1975-1979  (9)
  • 11
    Electronic Resource
    Electronic Resource
    Chichester : Wiley-Blackwell
    Organic Magnetic Resonance 8 (1976), S. 137-140 
    ISSN: 0030-4921
    Keywords: Chemistry ; Analytical Chemistry and Spectroscopy
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Notes: The chemical shifts and coupling constants for the ring protons of fourteen monosubstituted naphthalenes in carbon tetrachloride solution have been obtained by analysis and computer simulation of their 100 MHz magnetic resonance spectra. Studies at several concentrations have enabled shifts extrapolated to infinite dilution to be obtained and concentration effects arising from solute-solute interactions to be determined.
    Additional Material: 5 Tab.
    Type of Medium: Electronic Resource
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
  • 12
    ISSN: 0044-8249
    Keywords: Chemistry ; General Chemistry
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
  • 13
    ISSN: 0570-0833
    Keywords: Chemistry ; General Chemistry
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Additional Material: 1 Tab.
    Type of Medium: Electronic Resource
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
  • 14
    Electronic Resource
    Electronic Resource
    New York, NY : Wiley-Blackwell
    International Journal of Chemical Kinetics 24 (1992), S. 1043-1053 
    ISSN: 0538-8066
    Keywords: Chemistry ; Physical Chemistry
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Notes: The kinetics of the solvolysis of [Co(CN)5Cl]3- ions have been investigated in mixtures formed by the addition of ethane-1,2-diol or ethanonitrile to water where the physical properties indicate little enhancement of structure in water-rich conditions. The effect on the kinetics of this solvolysis of this lack of structural change in the solvent shows in the linearity of the variation of log (rate constant) with the reciprocal of the dielectric constant for the addition of ethane-1,2-diol to water and the absence of any prominent extrema in the enthalpy or entropy of activation using either co-solvent. However, the effect of changes in solvation on the solvolysis with these two co-solvents appears to operate in a similar manner to the effects found when the hydrophobic co-solvent propan-2-ol is added to water. The application of a free energy cycle to the process of the initial state going to the transition state for this dissociative process suggests that, with both co-solvents, [Co(CN)5]2- in the transition state is more stable than [Co(CN)5Cl]3- in the initial state. © John Wiley & Sons, Inc.
    Additional Material: 5 Ill.
    Type of Medium: Electronic Resource
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
  • 15
    Electronic Resource
    Electronic Resource
    Weinheim : Wiley-Blackwell
    Electrophoresis 15 (1994), S. 103-108 
    ISSN: 0173-0835
    Keywords: Chemistry ; Biochemistry and Biotechnology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Chemistry and Pharmacology
    Notes: A quantitative method for the determination of cocaine and related substances by micellar electrokinetic capillary chromatography (MECC) is described. Quantitative results obtained for both monitor materials and a number of actual drug seizures by this new capillary electrophoretic method are comparable to a gas chromatography (GC) run in parallel, both in the values and coefficient of variation achieved. The advantages of this new method include minimal use of solvents, the ability to readily automate the procedure and the ability to quantitate illicit heroin seizures under the same conditions with the exception of detector wavelength alteration. The method has proved rugged and reliable for both heroin and cocaine in a number of inter-laboratory proficiency studies.
    Additional Material: 6 Ill.
    Type of Medium: Electronic Resource
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
  • 16
    Electronic Resource
    Electronic Resource
    New York, NY : Wiley-Blackwell
    International Journal of Chemical Kinetics 7 (1975), S. 319-329 
    ISSN: 0538-8066
    Keywords: Chemistry ; Physical Chemistry
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Notes: The title reactions have been investigated in a static system. The addition of acetylene to cyclopentadiene (CPD) results in formation of norbornadiene (BCH), cycloheptatriene (CHT), and toluene (T), while BCH decomposition produces CPD, C2H2, CHT, and T. Kinetic studies, comprising both product-time evolution and initial pressure variation, support a mechanism These reactions are almost certainly homogeneous and molecular in nature. Least mean square analysis of the data yield for temperatures of 525-656°K, log k-1 (1./mole·s)=7.51±0.05- (24.19±0.15 kcal/mole)/RT ln 10, and for temperatures of 584-630°K, \documentclass{article}\pagestyle{empty}\begin{document}$$ \log k_1 (s^{ - 1}) = 14.78 \pm 0.10 - (51.37 \pm 0.29\,kcal/mole)/RT\ln 10 $$\end{document} \documentclass{article}\pagestyle{empty}\begin{document}$$ \log k_1 (s^{ - 1}) = 14.90 \pm 0.11 - (51.36 \pm 0.30\,kcal/mole)/RT\ln 10 $$\end{document}
    Additional Material: 2 Ill.
    Type of Medium: Electronic Resource
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
  • 17
    Electronic Resource
    Electronic Resource
    New York, NY : Wiley-Blackwell
    International Journal of Chemical Kinetics 22 (1990), S. 891-903 
    ISSN: 0538-8066
    Keywords: Chemistry ; Physical Chemistry
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Notes: Rates of solvolysis of ions [Co(3Rpy)4Cl2]+ with R = Me and Et have been measured over a range of temperatures for a series of water-rich water + methanol mixtures to investigate the effect of changes in solvent structure on the solvolysis of complexes presenting a largely hydrophobic surface to the solvent. The variation of the enthalpies and entropies of activation with solvent composition has been determined. A free energy cycle relating the free energy of activation in water to that in water + methanol is applied using free energies of transfer of individual ionic species from water into water + methanol. Data for the free energy of transfer of chloride ions ΔGt∘(Cl-) from both the spectrophotometric solvent sorting method and the TATB method for separating ΔGt∘(salt) into ΔGt∘(i) for individual ions are used: irrespective of the source of ΔGt∘(Cl-), in general, -ΔGt∘(Co(Rpy)4Cl2+) 〉 -ΔGt∘(Co(Rpy)4Cl2+), where Rpy = py, 4Mepy, 4Etpy, 3Etpy, and 3Mepy, showing that changes in solvent structure in water-rich water + methanol mixtures generally stabilize the cation in the transition state more than the cation in the initial state for this type of complex ion. A similar result is found when the free energy cycle is applied to the solvolysis of the dichloro (2,2′,2″-triaminotriethylamine)cobalt(III) ion. The introduction of a Me or Et group on the pyridine ring in [Co(Rpy)4Cl2]+ has little influence on the difference {ΔGt∘(Co(Rpy)4Cl2+)-ΔGt∘(Co(Rpy)4Cl2+)} in water + methanol with the mol fraction of methanol 〈 0.20.
    Additional Material: 6 Ill.
    Type of Medium: Electronic Resource
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
  • 18
    Electronic Resource
    Electronic Resource
    New York, NY : Wiley-Blackwell
    International Journal of Chemical Kinetics 23 (1991), S. 161-172 
    ISSN: 0538-8066
    Keywords: Chemistry ; Physical Chemistry
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Notes: Rates of solvolysis of complex ions [Co(3Rpy)4Cl2]+ with R = Me and Et have been determined in mixtures of water with the hydrophobic co-solvent propan-;2-ol for a range of temperatures. The variations of the enthalpies and entropies of activation with the solvent composition have been correlated with the physical properties of the solvent and it has been shown that the linear plot found for ΔH* against ΔS* in water + propan-2-ol is coincident with that found for water + methanol mixtures. A free energy cycle has been applied to the dissociative-type process of initial state (Cn+) going to the transition state (M(n+1)+…‥ Cl-) using values for the free energy of transfer of the chloride ion from water into the mixture, ΔGt∘(Cl-), derived from the solvent sorting technique or from the TATB/TPTB method. Irrespective of the source of ΔGt∘(Cl-), it is found that ΔGt∘(Co(3Rpy)4Cl2+*) ca. ΔGt∘(Co(3Rpy)4Cl2+) (where * indicates a species in the transition state) for mol fractions of propan-2-ol x2 ≳ 0.04-0.05 with ΔGt∘(Co(3Rpy)4Cl2+*) becoming increasingly more negative than ΔGt∘(Co(3Rpy)4Cl2+) as x2 increases above 0.05. These variations are compared with those for the solvolysis of the same ions in water + methanol mixtures and of a range of other ions in water + propan-2-ol mixtures. It is concluded that, using values for ΔGt∘(Cl-) from either source, the stabilizing influence of changes in solvent structure is greater on the cation in the transition state than on the cation in the initial state for the solvolyses of complexes [Co(Rpy)4Cl2+] and [Coen2LCl]n+.
    Additional Material: 6 Ill.
    Type of Medium: Electronic Resource
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
  • 19
    Electronic Resource
    Electronic Resource
    New York, NY : Wiley-Blackwell
    International Journal of Chemical Kinetics 24 (1992), S. 563-577 
    ISSN: 0538-8066
    Keywords: Chemistry ; Physical Chemistry
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Notes: Rates of solvolysis of complex ions [Co(3Rpy)4Cl2]+ with R = Me and Et have been determined in mixtures of water with t-butyl alcohol over a range of temperatures. Extrema found in the enthalpy ΔH* and entropy ΔS* of activation are correlated with the physical properties of the solvent mixtures which are influenced by changes in the solvent structure and these extrema are compared with those found for the solvolysis of related complexes in water + alcohol mixtures. Isokinetic plots over wide ranges of ΔH* and ΔS* are compared for the solvolysis of CoIII complexed to a variety of ligands. The application of a free energy cycle shows that the emergent cobalt (III) cation in the transition state becomes increasingly stabilized in water-rich mixtures relative to the cobalt (III) cation in the initial state as the mol fraction of t-butyl alcohol increases.
    Additional Material: 7 Ill.
    Type of Medium: Electronic Resource
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
  • 20
    Publication Date: 1990-12-21
    Description: Human growth hormone (hGH) elicits a diverse set of biological activities including lactation that derives from binding to the prolactin (PRL) receptor. The binding affinity of hGH for the extracellular binding domain of the hPRL receptor (hPRLbp) was increased about 8000-fold by addition of 50 micromolar ZnCl2. Zinc was not required for binding of hGH to the hGH binding protein (hGHbp) or for binding of hPRL to the hPRLbp. Other divalent metal ions (Ca2+, Mg2+, Cu2+, Mn2+, and Co2+) at physiological concentrations did not support such strong binding. Scatchard analysis indicated a stoichiometry of one Zn2+ per hGH.hPRLbp complex. Mutational analysis showed that a cluster of three residues (His18, His21, and Glu174) in hGH and His188 from the hPRLbp (conserved in all PRL receptors but not GH receptors) are probable Zn2+ ligands. This polypeptide hormone.receptor "zinc sandwich" provides a molecular mechanism to explain why nonprimate GHs are not lactogenic and offers a molecular link between zinc deficiency and its association with altered functions of hGH.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Cunningham, B C -- Bass, S -- Fuh, G -- Wells, J A -- New York, N.Y. -- Science. 1990 Dec 21;250(4988):1709-12.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Department of Protein Engineering, Genentech, Inc., South San Francisco, CA 94080.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/2270485" target="_blank"〉PubMed〈/a〉
    Keywords: Amino Acid Sequence ; Base Sequence ; Binding Sites ; Chlorides/*pharmacology ; Growth Hormone/*metabolism ; Humans ; Kinetics ; Models, Molecular ; Molecular Sequence Data ; Mutagenesis, Site-Directed ; Oligonucleotide Probes ; Plasmids ; Protein Conformation ; Receptors, Prolactin/drug effects/genetics/*metabolism ; Restriction Mapping ; Zinc/metabolism/*pharmacology ; *Zinc Compounds
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
Close ⊗
This website uses cookies and the analysis tool Matomo. More information can be found here...