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  • Blackwell Publishing Ltd  (2)
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  • 1
    ISSN: 1467-9310
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Economics
    Notes: Drug regulation and pricing have put strong pressure on the cost-benefit ratio of the innovative pharmaceutical industry. Therefore a study has been conducted in fourteen large and medium sized companies to determine some important organisational and managerial factors influencing success in pharmaceutical innovation. The study consists of structured interviews with Research Directors and questionnaires, submitted to the heads of the different research departments. The following conclusions are tentatively drawn. Firstly, the data suggest that a threshold investment of approximately $150–200 million is needed to maintain the innovative potential. Above approximately $750 million, ‘economies of scale’ seem to appear in pharmaceutical innovation. Secondly, an incremental strategy aimed at reducing the duration of the development process seems to be more successful than a radical strategy which lays more emphasis on discovery. Thirdly, pure play pharmaceuticals seem to be more successful than the pharmaceutical divisions of conglomerates. Management control, especially the way in which reorganisations are performed, is assessed more positively in pure play pharmaceuticals. Fourthly, the greater emphasis on human resources management in Anglo-American companies, in comparison to continental European companies, seems to be an important explanatory factor for their greater success on the pharmaceutical market.
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Publishing Ltd
    R & D management 18 (1988), S. 0 
    ISSN: 1467-9310
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Economics
    Notes: The paper contains a report of a test of Cooper's NewProd model for predicting success and failure of product development projects. Based on Canadian data, the model has been shown to make predictions which are 84% correct. Having reservations on the reliability and validity of the model on theoretical grounds, we set out to test it using data collected in the Netherlands.Following Cooper's methodology, we selected 19 projects, which had already been marketed and of which 9 were clearcut successes and 10 clearcut failures. We also studied 9 additional projects, which had not yet been commercialised, as the basis for a future a priori test. The projects were given a product score according to Cooper's criteria, and predictions compared with the actual experience. Eightyfour percent were correctly classified, as in Cooper's work. From a practical point of view however the variance was too large to allow the predictions from NewProd to be used with confidence to predict outcomes unless they are clearcut.We believe that the drawback of the methodology is that the product score is a simple combination of the various factors involved. No allowance is made for the possibility that one factor alone might be responsible for failure. We have therefore introduced the concept of a threshold value for each factor. A project for which any factor falls below this value will be deemed a failure. Based on a very limited sample of 19 cases an improvement of reliability was made to 95% of 18 out of 19 products correctly classified. The NewProd concept so modified is being applied to the sample of 9 as yet uncompleted projects, and its predictions will eventually be compared with actual outcomes.
    Type of Medium: Electronic Resource
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