ISSN:
1432-0983
Keywords:
Key words SSB-homolog
;
Regulation
;
Gene expression
;
Budding yeast
;
Glucose effect
Source:
Springer Online Journal Archives 1860-2000
Topics:
Biology
Notes:
Abstract The mitochondrial single-stranded DNA-binding protein (SSB) encoded by a nuclear gene, RIM1, is a homolog of Escherichia coli SSB. The addition of glucose decreased the amount of RIM1-mRNA in cells growing in a glycerol medium, but increased the amount of the immature RIM1-mRNA. The changes in the amounts of both mature and immature RIM1-mRNAs were dependent on SRN1/REG1/HEX2, a gene relating to pre-mRNA-splicing and glucose repression. These observations suggest that the expression of the mitochondrial SSB is regulated, at least in part, by pre-mRNA splicing under the control of glucose repression.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/s002940050406
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