ALBERT

All Library Books, journals and Electronic Records Telegrafenberg

X
feed icon rss

Your email was sent successfully. Check your inbox.

An error occurred while sending the email. Please try again.

Proceed reservation?

Export
  • 1
    Electronic Resource
    Electronic Resource
    Alteration of the omega-3 fatty acid desaturase gene is associated with reduced linolenic acid in the A5 soybean genotype (1997)
    Springer
    Theoretical and applied genetics 94 (1997), S. 356-359 
    Details
    ISSN: 1432-2242
    Keywords: Key words Soybean ; Glycine max (L.) Merr ; Linolenic acid ; Omega-3 fatty acid desaturase
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Abstract  Reducing the linolenic acid (18 : 3ω  3,6,9) concentration of soybean [Glycine max (L.) Merr.] oil may lessen the need for chemical hydrogenation and enhance flavor stability. Soybean genotypes A5 and A23 have reduced linolenic acid concentration compared with current cultivars. Seed linolenic acid is synthesized primarily by the ω-3 fatty acid desaturase located in the microsomes. The objective of this research was to study whether this enzyme has a role in reducing the fatty acid levels in the soybean genotypes A5 and A23. DNA from A5 and A23 was analyzed by gel-blot hybridization with a cDNA encoding the ω-3 fatty acid desaturase. A5 and lines selected from it have a DNA fragment missing compared to A23 and lines with normal linolenic acid concentration. Seventy F4:5 lines from a population segregating for linolenic acid concentration were scored for presence or absence of the fragment. The absence of the fragment was significantly (P?0.0001) associated with a reduced linolenic acid level and accounted for 67% of the variation for linolenic acid in the population. These results suggest that the reduced linolenic acid concentration in A5 was at least partially the result of a full or partial deletion of a microsomal ω-3 desaturase gene. No DNA polymorphisms were found for the desaturase gene in A23, so no mutations could be studied in this line.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s001220050423
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 2
    facet.materialart.
    Unknown
    Decreased muscarinic receptor binding in the arcuate nucleus in sudden infant death syndrome (1995)
    American Association for the Advancement of Science (AAAS)
    Details
    Publication Date: 1995-09-08
    Description: Muscarinic cholinergic activity in the human arcuate nucleus at the ventral medullary surface is postulated to be involved in cardiopulmonary control. A significant decrease in [3H]quinuclidinyl benzilate binding to muscarinic receptors in the arcuate nucleus is now shown to occur in sudden infant death syndrome (SIDS) infants, compared to infants dying acutely of known causes. In infants with chronic oxygenation abnormalities, binding is low in other nuclei, as well as in the arcuate nucleus. The binding deficit in the arcuate nucleus of SIDS infants might contribute to a failure of responses to cardiopulmonary challenges during sleep.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Kinney, H C -- Filiano, J J -- Sleeper, L A -- Mandell, F -- Valdes-Dapena, M -- White, W F -- P30-HD18655/HD/NICHD NIH HHS/ -- R01-HD20991/HD/NICHD NIH HHS/ -- New York, N.Y. -- Science. 1995 Sep 8;269(5229):1446-50.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Department of Pathology, Children's Hospital, Boston, MA, USA.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/7660131" target="_blank"〉PubMed〈/a〉
    Keywords: Acute Disease ; Anoxia/metabolism ; Arcuate Nucleus of Hypothalamus/*metabolism ; Autoradiography ; Brain Stem/metabolism ; Chronic Disease ; Humans ; Infant ; Infant, Newborn ; Quinuclidinyl Benzilate/*metabolism ; Receptors, Muscarinic/*metabolism ; Sudden Infant Death/*etiology
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
    Published by American Association for the Advancement of Science (AAAS)
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
    PAPER CURRENT
Close ⊗
This website uses cookies and the analysis tool Matomo. More information can be found here...