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  • 1
    Publication Date: 1995-09-08
    Description: Muscarinic cholinergic activity in the human arcuate nucleus at the ventral medullary surface is postulated to be involved in cardiopulmonary control. A significant decrease in [3H]quinuclidinyl benzilate binding to muscarinic receptors in the arcuate nucleus is now shown to occur in sudden infant death syndrome (SIDS) infants, compared to infants dying acutely of known causes. In infants with chronic oxygenation abnormalities, binding is low in other nuclei, as well as in the arcuate nucleus. The binding deficit in the arcuate nucleus of SIDS infants might contribute to a failure of responses to cardiopulmonary challenges during sleep.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Kinney, H C -- Filiano, J J -- Sleeper, L A -- Mandell, F -- Valdes-Dapena, M -- White, W F -- P30-HD18655/HD/NICHD NIH HHS/ -- R01-HD20991/HD/NICHD NIH HHS/ -- New York, N.Y. -- Science. 1995 Sep 8;269(5229):1446-50.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Department of Pathology, Children's Hospital, Boston, MA, USA.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/7660131" target="_blank"〉PubMed〈/a〉
    Keywords: Acute Disease ; Anoxia/metabolism ; Arcuate Nucleus of Hypothalamus/*metabolism ; Autoradiography ; Brain Stem/metabolism ; Chronic Disease ; Humans ; Infant ; Infant, Newborn ; Quinuclidinyl Benzilate/*metabolism ; Receptors, Muscarinic/*metabolism ; Sudden Infant Death/*etiology
    Print ISSN: 0036-8075
    Electronic ISSN: 1095-9203
    Topics: Biology , Chemistry and Pharmacology , Computer Science , Medicine , Natural Sciences in General , Physics
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  • 2
    Publication Date: 2019-08-15
    Description: Our analysis allowed us to address the following points: 1) the nature of the featureless ultraviolet continuum in Seyfert 2's, in particular the amount of stellar population that contributes to this waveband; 2) the difference between Seyfert l's and Seyfert 2's in the ratio of ultraviolet (lambda)1400A to soft X-rays continuum, which is larger in Seyfert 2's and apparently contradicts the Unified Model, but may be resolved if we consider the stellar population; 3) search for anisotropic radiation escaping from the nucleus of Seyfert 2's, by comparing the number of ionizing photons, estimated from the ultraviolet continuum photons, to the number of recombination photons, calculated using the H(beta) line flux. In addition, the research from this grant produced template spectra that have been used in a wide variety of applications, including the identification of high redshift galaxies in the Slone survey.
    Keywords: Astrophysics
    Format: application/pdf
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