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  • Cardiovascular tissues  (2)
  • Isopachs  (2)
  • Springer  (4)
  • 1995-1999  (4)
Collection
Publisher
  • Springer  (4)
Years
  • 1995-1999  (4)
Year
  • 1
    Electronic Resource
    Electronic Resource
    Springer
    International journal of earth sciences 84 (1995), S. 293-318 
    ISSN: 1437-3262
    Keywords: Saar-Nahe Basin ; Strike-slip basin ; Tectonic subsidence curves ; Variscan tectonics ; Cross-sections ; Isopachs
    Source: Springer Online Journal Archives 1860-2000
    Topics: Geosciences
    Notes: Abstract The Permo-Carboniferous Saar-Nahe Basin in south-west Germany and north-east France formed at the boundary between the Rhenohercynian and Saxothuringian zones within the Variscan orogen, where non-marine sediments were deposited in a narrow, structurally controlled basin. The basin has an asymmetrical geometry perpendicular to the South Hunsruck Fault. However, there is a lack of growth of the sediment pile into the fault, and isopach maps show the depocentre always located adjacent to the South Hunsrück Fault, but migrating towards the north-east with time. This pattern is typical of a strike-slip basin, indicating that the South Hunsruck Fault was a dextral strike-slip fault during sedimentation. Tectonic subsidence curves indicate that, during the Middle Devonian to Early Carboniferous, the basin subsided due to thermal relaxation of the lithosphere. A change to very rapid subsidence at the start of the Westphalian continued until late in the Autunian. This was due to mechanical subsidence associated with strike-slip movement on the South Hunsruck Fault. Towards the end of subsidence in the Saar-Nahe Basin, the Grenzlager volcanics introduced a thermal pulse into the crust, leading to thermal cooling and relaxation of the lithosphere.
    Type of Medium: Electronic Resource
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  • 2
    ISSN: 1432-0878
    Keywords: Key words: In situ hybridization ; Immunohistochemistry ; Pro-hormone convertases ; Cardiovascular tissues ; Pro-atrial natriuretic factor ; Pro-endothelin ; Processing ; Rat (Sprague Dawley)
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Abstract. The present study examined the distribution of the pro-hormone convertases PC1, PC2, furin, PACE4 and PC5 in the rat heart. Northern blot analysis of RNA extracted from cardiac tissues showed high levels of furin and PACE4 mRNA in the atria and ventricles, while PC5 mRNA was found to be expressed at high levels in the dorsal aorta. Although undetectable by Northern blot analysis, both PC1 and PC2 mRNA were detected by in situ hybridization and immunohistochemistry in discrete regions of the intracardiac para-aortic ganglia. In situ hybridization studies also showed that furin mRNA was observed in all cardiac tissues and cells, consistent with the previously reported ubiquitous expression of this gene. PACE4 mRNA was highly abundant in both the atria and ventricular cardiomyocytes, with low to undetectable levels observed in blood vessels. Finally, PC5 transcripts were expressed in the endothelial cells lining coronary vessels and the valve leaflets of the heart. The present localization studies in the heart and cardiac blood vessels suggests potential roles for each convertase in the processing of various neuropeptides, hormones and growth factors.
    Type of Medium: Electronic Resource
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  • 3
    ISSN: 1432-0878
    Keywords: In situ hybridization ; Immunohistochemistry ; Pro-hormone convertases ; Cardiovascular tissues ; Pro-atrial natriuretic factor ; Pro-endothelin ; Processing ; Rat (Sprague Dawley)
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Abstract The present study examined the distribution of the pro-hormone convertases PC1, PC2, furin, PACE4 and PC5 in the rat heart. Northern blot analysis of RNA extracted from cardiac tissues showed high levels of furin and PACE4 mRNA in the atria and ventricles, while PC5 mRNA was found to be expressed at high levels in the dorsal aorta. Although undetectable by Northern blot analysis, both PC1 and PC2 mRNA were detected by in situ hybridization and immunohistochemistry in discrete regions of the intracardiac para-aortic ganglia. In situ hybridization studies also showed that furin mRNA was observed in all cardiac tissues and cells, consistent with the previously reported ubiquitous expression of this gene. PACE4 mRNA was highly abundant in both the atria and ventricular cardiomyocytes, with low to undetectable levels observed in blood vessels. Finally, PC5 transcripts were expressed in the endothelial cells lining coronary vessels and the valve leaflets of the heart. The present localization studies in the heart and cardiac blood vessels suggests potential roles for each convertase in the processing of various neuropeptides, hormones and growth factors.
    Type of Medium: Electronic Resource
    Location Call Number Expected Availability
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  • 4
    ISSN: 0016-7835
    Keywords: Key words Saar-Nahe Basin ; Strike-slip basin ; Tectonic subsidence curves ; Variscan tectonics ; Cross-sections ; Isopachs
    Source: Springer Online Journal Archives 1860-2000
    Topics: Geosciences
    Notes: Abstract  The Permo-Carboniferous Saar-Nahe Basin in south-west Germany and north-east France formed at the boundary between the Rhenohercynian and Saxothuringian zones within the Variscan orogen, where non-marine sediments were deposited in a narrow, structurally controlled basin. The basin has an asymmetrical geometry perpendicular to the South Hunsrück Fault. However, there is a lack of growth of the sediment pile into the fault, and isopach maps show the depocentre always located adjacent to the South Hunsrück Fault, but migrating towards the north-east with time. This pattern is typical of a strike-slip basin, indicating that the South Hunsrück Fault was a dextral strike-slip fault during sedimentation. Tectonic subsidence curves indicate that, during the Middle Devonian to Early Carboniferous, the basin subsided due to thermal relaxation of the lithosphere. A change to very rapid subsidence at the start of the Westphalian continued until late in the Autunian. This was due to mechanical subsidence associated with strike-slip movement on the South Hunsrück Fault. Towards the end of subsidence in the Saar-Nahe Basin, the Grenzlager volcanics introduced a thermal pulse into the crust, leading to thermal cooling and relaxation of the lithosphere.
    Type of Medium: Electronic Resource
    Location Call Number Expected Availability
    BibTip Others were also interested in ...
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