ISSN:
1476-4687
Source:
Nature Archives 1869 - 2009
Topics:
Biology
,
Chemistry and Pharmacology
,
Medicine
,
Natural Sciences in General
,
Physics
Notes:
[Auszug] We used gene targeting to disrupt exon 14 of the Ace gene in a subline, BK4, of E14TG2a17 strain 129 embryonic stem cells (Fig. 1). Exon 14 encodes amino acids critical for the normal function of both testis and somatic ACE18. Male chimaeras derived from the stem cells were mated with C57BL/6J ...
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1038/375146a0
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