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  • 1
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Publishing Ltd
    Soil use and management 15 (1999), S. 0 
    ISSN: 1475-2743
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Geosciences , Agriculture, Forestry, Horticulture, Fishery, Domestic Science, Nutrition
    Notes: Abstract. Sustaining soil fertility under agricultural intensification and expansion onto marginal lands is a significant challenge in the Nepalese Middle Mountains. In a detailed watershed study it was shown that the overall soil fertility is poor, forest soils display the poorest conditions as a result of biomass removal, and sustaining agriculture is questionable due to the transformation from traditional to multiple cropping systems. Parent material is a significant factor influencing low phosphorus status while insufficient inputs create deficiencies in total carbon, nitrogen and bases. A nutrient budget model was developed to assess inputs, redistribution and losses relative to soil fertility. Yield, input and management data obtained from farm interviews, and soil analysis data were used in the calculation of nutrient budgets. Results from modelling indicate declining soil fertility under rainfed agriculture, forest and rangelands, and marginal conditions under irrigated agriculture subject to intensive cultivation. Nutrient deficits were relatively low for irrigated rice-wheat systems, which benefit from nutrient inputs via sediments and irrigation waters, but the introduction of triple cropping showed greater deficits. Nutrient balances were most critical under rainfed maize production where 94% of the farms were in deficit. Current shortages of organic matter make elimination of nutrient deficits problematic but improvement of composting, biological N-fixation and fertilizer efficiency and reducing erosion were found to be potential options.
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Publishing Ltd
    Aquaculture research 27 (1996), S. 0 
    ISSN: 1365-2109
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Agriculture, Forestry, Horticulture, Fishery, Domestic Science, Nutrition
    Notes: Extracellular-enzyme activity (i.e. external to cytoplasmic membranes) increased in water flowing through trout farms. Directly counted bacteria also increased, but partitioning of extracellular-enzyme activity in outflow water by 0.2 μm filtration showed that a substantial proportion was often free rather than cell-associated, and might have originated as free enzymes released by enriched sediments or by fish. Discharges from four trout farms caused marked increases in extracellular-enzyme activity along a 13-km length of river, which were sometimes sufficient to swamp native enzyme activity. The pollutant enzymes might have facilitated bio-purification in the river. Artificially increased extracellular-enzyme activity in the river was accompanied by increase in bacterioplankton and phytoplankton chlorophyll, but partitioning showed that most of the increases in leucine aminopeptidase and phosphatase activity were due to free enzymes. In contrast, increase in β-glucosidase activity was perhaps more associated with bacterial and/or algal cells.
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Publishing Ltd
    Marine mammal science 15 (1999), S. 0 
    ISSN: 1748-7692
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Biology
    Type of Medium: Electronic Resource
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  • 4
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Publishing Ltd
    Annals of the New York Academy of Sciences 791 (1996), S. 0 
    ISSN: 1749-6632
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Natural Sciences in General
    Type of Medium: Electronic Resource
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  • 5
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Publishing Ltd
    Annals of the New York Academy of Sciences 777 (1996), S. 0 
    ISSN: 1749-6632
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Natural Sciences in General
    Notes: All individuals with Down's syndrome (trisomy 21-DS) develop the pathogenic hallmarks of Alzheimer's disease in old age (+40 years).1-4 The extent of pathology is variable, but it has been shown that the amount of β-amyloid pathology is variable and related to age and the degree of dementia.3 Thus, in DS, growing old is associated with a progressive pathological process which results in cognitive decline. However, neuropsychological studies of older DS subjects have identified a clinical dementia in only a proportion of cases.1-4These contradictory observations could be reconciled if some factor existed which modulated the rate and amount of β-amyloid pathology. Recent studies demonstrate an association between the apolipoprotein E4 (ApoE4) allele and the earlier age of onset in both sporadic8-9 and familial10 AD. Increased amounts of βamyloid pathology can also be related to the E4 allele. However, at present there are no data documenting the effects of ApoE genotype on the expression or degree of clinical symptoms of the disease. We have examined the ApoE genotype in a cohort of clinically evaluated elderly patients with DS in order to examine the effects of ApoE genotype on the clinical symptoms of dementia. We report here that, despite the presence of an active disease process, the ApoE E2 allele is associated with longevity and preservation of cognitive functioning.
    Type of Medium: Electronic Resource
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