Publication Date:
1997-06-27
Description:
Parsley cells recognize the fungal plant pathogen Phytophthora sojae through a plasma membrane receptor. A pathogen-derived oligopeptide elicitor binds to this receptor and thereby stimulates a multicomponent defense response through sequential activation of ion channels and an oxidative burst. An elicitor-responsive mitogen-activated protein (MAP) kinase was identified that acts downstream of the ion channels but independently or upstream of the oxidative burst. Upon receptor-mediated activation, the MAP kinase is translocated to the nucleus where it might interact with transcription factors that induce expression of defense genes.〈br /〉〈span class="detail_caption"〉Notes: 〈/span〉Ligterink, W -- Kroj, T -- zur Nieden, U -- Hirt, H -- Scheel, D -- New York, N.Y. -- Science. 1997 Jun 27;276(5321):2054-7.〈br /〉〈span class="detail_caption"〉Author address: 〈/span〉Institute of Microbiology and Genetics, Vienna Biocenter, Dr.-Bohr-Gasse 9, A-1030 Vienna, Austria.〈br /〉〈span class="detail_caption"〉Record origin:〈/span〉 〈a href="http://www.ncbi.nlm.nih.gov/pubmed/9197271" target="_blank"〉PubMed〈/a〉
Keywords:
Amino Acid Sequence
;
Amphotericin B/pharmacology
;
Anthracenes/pharmacology
;
Calcium-Calmodulin-Dependent Protein Kinases/chemistry/genetics/*metabolism
;
Cell Nucleus/enzymology
;
Cells, Cultured
;
Enzyme Activation
;
Fungal Proteins/*pharmacology
;
Ion Channels/drug effects/metabolism
;
Membrane Glycoproteins/*pharmacology
;
Molecular Sequence Data
;
Onium Compounds/pharmacology
;
Peptide Fragments/pharmacology
;
Phosphorylation
;
Phytophthora/metabolism
;
Plants/*enzymology/genetics/microbiology
;
Respiratory Burst/drug effects
Print ISSN:
0036-8075
Electronic ISSN:
1095-9203
Topics:
Biology
,
Chemistry and Pharmacology
,
Computer Science
,
Medicine
,
Natural Sciences in General
,
Physics
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