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  • Biomarkers  (2)
  • Wiley-Blackwell  (2)
  • American Association of Petroleum Geologists (AAPG)
  • American Physical Society
  • Cambridge University Press
  • 1995-1999  (2)
  • 1965-1969
Collection
Publisher
  • Wiley-Blackwell  (2)
  • American Association of Petroleum Geologists (AAPG)
  • American Physical Society
  • Cambridge University Press
Years
  • 1995-1999  (2)
  • 1965-1969
Year
  • 1
    Electronic Resource
    Electronic Resource
    New York, N.Y. : Wiley-Blackwell
    Journal of Cellular Biochemistry 59 (1995), S. 243-246 
    ISSN: 0730-2312
    Keywords: Biomarkers ; chemoprevention ; ovarian cancer ; Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Chemistry and Pharmacology , Medicine
    Notes: Epithelial ovarian cancer is a heterogenous disease. Epidemiologic studies have identified risk factors for this disease including advanced age, nulliparity, history of infertility, early age at menarche, late age at menopause, and perhaps ovulation induction. Cohort selection that includes women who have potential precursor lesions and alterations of select biomarkers may prove useful in the design of chemoprevention trials of epithelial ovarian cancer. Nuclear morphometry, specific genetic alterations, and markers of proliferation and differentiation may be useful biomarker to monitor the efficacy of specific interventions.
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    New York, N.Y. : Wiley-Blackwell
    Journal of Cellular Biochemistry 59 (1995), S. 184-188 
    ISSN: 0730-2312
    Keywords: Biomarkers ; chemoprevention ; endometrial cancer ; uterine cancer ; Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Chemistry and Pharmacology , Medicine
    Notes: Women at risk of uterine cancer include those with one or more of the following characteristics: obesity, nulliparity, late menopause, diabetes mellitus, prolonged unopposed estrogen use, and tamoxifen therapy. Risk is additionally increased by the presence of endometrial hyperplasia. The incorporation of biomarkers into the selection criteria of cohort groups at risk for developing endometrial cancer offers an innovative approach to the clinical design of chemoprevention trials of endometrial adenocarcinoma. Biomarkers that may be useful in cohort selection include nuclear morphometry, specific genetic abnormalities, and markers of proliferation and differentiation.
    Type of Medium: Electronic Resource
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