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  • Articles  (11)
  • Wiley-Blackwell  (11)
  • 1995-1999  (9)
  • 1970-1974  (2)
  • Chemistry and Pharmacology  (9)
  • Medicine  (2)
  • Mathematics
Collection
  • Articles  (11)
Source
Keywords
Publisher
Years
Year
Topic
  • 1
    Electronic Resource
    Electronic Resource
    Molecular dynamics of a hemoglobin crosslinking reaction (1996)
    New York : Wiley-Blackwell
    Biopolymers 39 (1996), S. 615-618 
    Details
    ISSN: 0006-3525
    Keywords: Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Notes: No abstract.
    Additional Material: 6 Ill.
    Type of Medium: Electronic Resource
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    Paper (German National Licenses)
  • 2
    Electronic Resource
    Electronic Resource
    2. Deutsch-Dänisches Symposium über Organische Chemie: 1,2,3-Triazoline (1974)
    Weinheim : Wiley-Blackwell
    Zeitschrift für die chemische Industrie 86 (1974), S. 315-315 
    Details
    ISSN: 0044-8249
    Keywords: Chemistry ; General Chemistry
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/ange.19740860814
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  • 3
    Electronic Resource
    Electronic Resource
    An introduction to blood compatible polymer surfaces for use in artificial internal organsPresented in part at the 68th National Meeting, American Institute of Chemical Engineers, Houston, Texas, February 28-March 4, 1971. (1973)
    Stamford, Conn. [u.a.] : Wiley-Blackwell
    Polymer Engineering and Science 13 (1973), S. 241-247 
    Details
    ISSN: 0032-3888
    Keywords: Chemistry ; Chemical Engineering
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology , Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics , Physics
    Notes: While the body is a hostile environment for all types of polymers, an even more serious problem is that of thrombus formation induced by all foreign surfaces, including polymeric surfaces. This is a still largely unsolved problem which hinders the development of artificial internal organs. The thromboresistant materials presently proposed and used in artificial organs include heparinized surfaces and materials found to be thromboresistant in certain implantation cites. In this article tissue-polymer interactions are first discussed and then followed by a discussion of blood-polymer interactions. The mechanism of thrombus formation is presented and some of the possible interactions of blood with surfaces are suggested. Representative nonthrombogenic and thromboresistant materials are discussed.
    Additional Material: 4 Tab.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/pen.760130402
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  • 4
    Electronic Resource
    Electronic Resource
    Voltammetric sensor for uranium based on the propyl gallate- modified carbon paste electrode (1995)
    Weinheim : Wiley-Blackwell
    Electroanalysis 7 (1995), S. 247-250 
    Details
    ISSN: 1040-0397
    Keywords: Uranium ; Sensor ; Remote sensing ; Field screening ; Modified electrode ; Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Notes: A carbon paste electrode modified with the ligand propyl gallate is introduced for preconcentration/voltammetric measurements of low levels of uranium. The resulting preconcentrating electrode offers many attractive properties for on-site sensing of uranium, including high sensitivity and selectivity, self-cleaning capability, and use of nondeaerated quiescent solutions. The response is characterized with respect to the paste composition, preconcentration period, solution and differential pulse conditions, and other variables. The sensor displays high stability, and can be used repeatedly without regeneration. When coupled to a 100-ft (30.5-m) long shielded cable, the electrode offers a remote sensing capability, as illustrated in the determination of uranium in groundwater.
    Additional Material: 9 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/elan.1140070308
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  • 5
    Electronic Resource
    Electronic Resource
    Detection of glucose at a rotating gold composite electrode by pulsed amperometric detection (1996)
    Weinheim : Wiley-Blackwell
    Electroanalysis 8 (1996), S. 443-446 
    Details
    ISSN: 1040-0397
    Keywords: Glucose ; Composite electrodes ; Pulsed amperometry ; Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Notes: Segregated composite electrodes mimic microelectrode ensembles. In this preliminary report, the use of a rotating gold-polychlorotri- fluoroethylene (or Kel-F, a 3M Company polymer) composite electrode in combination with pulsed amperometric detection (PAD) is described for the detection of glucose. Comparisons are made with results obtained at a solid gold disk electrode. The composite electrode exhibits a higher signal and a lower background than does the solid gold electrode. In terms of current density, the enhancement of the signal above the background is over 3-fold, similar to that observed with segregated graphite composite electrodes used in a constant potential mode. Little or no glucose signal is observed at either the solid gold or the gold composite electrode when employed in the constant potential mode. In the PAD mode, the signal is stable for periods in excess of an hour.
    Additional Material: 4 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/elan.1140080508
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  • 6
    Electronic Resource
    Electronic Resource
    Next generation risk management (1997)
    New York, NY [u.a.] : Wiley-Blackwell
    Process Safety Progress 16 (1997), S. 69-71 
    Details
    ISSN: 1066-8527
    Keywords: Chemistry ; Chemical Engineering
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: The management of safety, quality and environmental issues covers a complex set of interrelated issues of concern to society and industry. Traditionally an engineering approach has been adopted for the management of risk; the development of technical standards, operations and requirements. Recently, industry leaders have begun to realize that real progress will be made only throgh effective risk management systems. This paper presents a few of the key requirements for improving risk management and risk analysis. By improving the way risk analysis is used for decision support, improving hazard identification exercise, while incorporating site specific properties of design, condition, operation and management into an analysis, it is possible to improve the value of current risk management techniques.
    Additional Material: 2 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/prs.680160204
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  • 7
    Electronic Resource
    Electronic Resource
    Flow cytometry for assessing biocompatibility (1998)
    Hoboken, NJ : Wiley-Blackwell
    Journal of Biomedical Materials Research 41 (1998), S. 649-656 
    Details
    ISSN: 0021-9304
    Keywords: flow cytometry ; cell culture ; biocompatibility ; biomaterials ; implants ; Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Medicine , Technology
    Notes: Flow cytometry (FCM) was examined as a possible procedure for measuring in vitro the biocompatibility of implant materials for orthopedic and dental surgery. The human osteoblast-like cell line MG63 was grown on hydroxyapatite (HA) and P2O5 glass-reinforced HA composite discs and compared with the same cells grown on polystyrene culture dishes. While morphological observation at the light and electron microscopic levels showed no major deleterious effects, FCM indicated that cell size was somewhat reduced, particularly by growth on the HA composite. Moreover, this material also appeared to delay the progression of the cells from the G0/G1 into the S phase of the cell cycle. In addition to this low level of inhibition of cell growth relative to control cultures, FCM analysis also demonstrated that the glass-reinforced HA caused some down-regulation of the expression of osteocalcin and fibronectin, two antigens which play a vital part in the integrity and function of bone and soft connective tissue, respectively. These results thus show, first, that although HA and the HA composite used in these experiments were generally biocompatible, they nevertheless had certain suboptimal effects on the cells; and second, that FCM could be a highly useful procedure for effectively screening and evaluating important biological responses to implant materials. © 1998 John Wiley & Sons, Inc. J Biomed Mater Res, 41, 649-656, 1998.
    Additional Material: 7 Ill.
    Type of Medium: Electronic Resource
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  • 8
    Electronic Resource
    Electronic Resource
    Spin-orbit and correlation effects in platinum hydride (PtH) (1998)
    New York, NY : Wiley-Blackwell
    International Journal of Quantum Chemistry 68 (1998), S. 53-64 
    Details
    ISSN: 0020-7608
    Keywords: Chemistry ; Theoretical, Physical and Computational Chemistry
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Notes: The low-lying electronic states of PtH were studied by all-electron one- and two-component variational calculations on the multireference CI levels. The orbital optimization is performed within a one-component formalism, whereas the further refinement of the wave functions follows two different schemes: The most demanding approach introduces spin-orbit coupling in the CI optimization step, giving a simultaneous treatment of electron correlation and spin-orbit coupling. The second, considerably less demanding approach, corresponds almost to a perturbational treatment, introducing spin-orbit coupling as a final step after the CI optimization by diagonalizing the resulting Hamiltonian matrix over CI states.   © 1998 John Wiley & Sons, Inc. Int J Quant Chem 68: 53-64, 1998
    Additional Material: 9 Tab.
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  • 9
    Electronic Resource
    Electronic Resource
    Pattern and process of wall formation in developing endosperm (1995)
    New York, NY : Wiley-Blackwell
    BioEssays 17 (1995), S. 803-812 
    Details
    ISSN: 0265-9247
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Medicine
    Notes: Endosperm is emerging as a system for investigating the genetic control of wall placement and deposition in plant development. Development of endosperm progresses in distinct stages from a wall-less syncytial stage to a cellular stage that is entirely typical of plant meristems where the division plane is predicted by a preprophase band of microtubules (PPB) and cytokinesis is completed by formation of a cell plate in association with a phragmoplast. Four developmentally different types of walls, each associated with a different microtubule system, are sequentially produced: (1) free growing walls deposited in the absence of mitosis and phragmoplasts; (2) walls guided by cytoplasmic phragmoplasts formed adventitiously in the absence of mitosis; (3) walls formed by interzonal phragmoplasts in a cell cycle that lacks PPBs; and (4) wall deposition driven by interzonal phragmoplasts in a cycle that includes PPBs. We are using methods of differential screening to isolate cDNA clones corresponding in temporal and spatial pattern to the types of wall development, and are studying mutants for clues to the genetic controls of wall development.
    Additional Material: 4 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/bies.950170910
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  • 10
    Electronic Resource
    Electronic Resource
    The human keratinocyte two-dimensional gel protein database (update 1995): Mapping components of signal transduction pathways (1995)
    Weinheim : Wiley-Blackwell
    Electrophoresis 16 (1995), S. 2177-2240 
    Details
    ISSN: 0173-0835
    Keywords: Two-dimensional gel protein database ; Keratinocytes ; Protein identification ; Signal transduction components ; Global cell regulation ; Chemistry ; Biochemistry and Biotechnology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Chemistry and Pharmacology
    Notes: The master two-dimensional (2-D) gel database of human keratinocytes currently lists 3154 cellular proteins (2224 isoelectric focusing, IEF; and 930 none-quilibrium pH gradient electrophoresis, NEPHGE), many of which correspond to post-translational modifications. 1082 polypeptides have been identified (protein name, organelle components, etc.) using a procedure or a combination of procedures that include (i) comigration with known human proteins, (ii) 2-D gel immunoblotting using specific antibodies, (iii) microsequencing of Coomassie Brilliant Blue stained proteins, (iv) mass spectrometry, (v) vaccinia virus expression of full length cDNAs, and (vi) in vitro transcription/translation of full-length cDNAs. This year, special emphasis has been given to the identification of signal transduction components by using 2-D gel immunoblotting of crude keratinocyte lysates in combination with enhanced chemoluminescence (ECL) detection. Identified proteins are listed both in alphabetical order and with increasing SSP number, together with their Mr, pI, cellular localization and credit to the investigator(s) that aided in the identification. Ultimately, the aim of the comprehensive database is to gather - through a systematic study of ekeratinocytes - qualitative and quantitative information on proteins and their genes that may allow us to identify abnormal patterns of gene expression and to pinpoint signaling pathways and components affected in various skin diseases, cancer included.
    Additional Material: 7 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/elps.11501601355
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