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Digitale Medien

Evolution of the aminoacyl-tRNA synthetases and the origin of the genetic code (1995)

Wetzel, R.

Springer

Journal of molecular evolution 40 (1995), S. 545-550

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ISSN: 1432-1432

Schlagwort(e): Genetic code ; Aminoacyl-tRNA synthetases ; Ribozyme ; Protein design ; Leucine zippers

Quelle: Springer Online Journal Archives 1860-2000

Thema: Biologie

Notizen: Abstract The aminoacyl-tRNA synthetases exist as two enzyme families which were apparently generated by divergent evolution from two primordial synthetases. The two classes of enzymes exhibit intriguing familial relationships, in that they are distributed nonrandomly within the codon-amino acid matrix of the genetic code. For example, all XCX codons code for amino acids handled by class II synthetases, and all but one of the XUX codons code for amino acids handled by class I synthetases. One interpretation of these patterns is that the synthetases coevolved with the genetic code. The more likely explanation, however, is that the synthetases evolved in the context of an already-established genetic code—a code which developed earlier in an RNA world. The rules which governed the development of the genetic code, and led to certain patterns in the coding catalog between codons and amino acids, would also have governed the subsequent evolution of the synthetases in the context of a fixed code, leading to patterns in synthetase distribution such as those observed. These rules are (1) conservative evolution of amino acid and adapter binding sites and (2) minimization of the disruptive effects on protein structure caused by codon meaning changes.

Materialart: Digitale Medien

URL: http://dx.doi.org/10.1007/BF00166624

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Digitale Medien

Two-dimensional wannier excitons. Effects of a random adiabatic potential (1995)

Efros, Al. L. ; Wetzel, C. ; Worlock, J. M.

Springer

Il nuovo cimento della Società Italiana di Fisica 17 (1995), S. 1447-1452

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ISSN: 0392-6737

Schlagwort(e): Excitons and related phenomena (including electron-hole drops) ; Optical properties of thin films, surfaces, and layer structures (superlattices, heterojunctions, and multilayers) ; Conference proceedings

Quelle: Springer Online Journal Archives 1860-2000

Thema: Physik

Notizen: Summary We investigate the absorption spectrum and the distribution of radiative decay times for two-dimensional excitons in semiconductor quantum wells, as affected by an adiabatic white-noise random potential. Such a potential could result from atomic-scale fluctuations in the composition of an alloy semiconductor, or in quantum well thickness. We find in general that the shortest radiative decay time is directly proportional to the inhomogeneous width of the exciton line in absorption, itself proportional to the correlation parameter for the random potential.

Materialart: Digitale Medien

URL: http://dx.doi.org/10.1007/BF02457225

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