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  • 1
    Electronic Resource
    Electronic Resource
    Springer
    Agriculture and human values 15 (1998), S. 115-120 
    ISSN: 1572-8366
    Keywords: Medicine ; Veterinary medicine ; Public health ; Epidemiology ; Comparative medicine
    Source: Springer Online Journal Archives 1860-2000
    Topics: Agriculture, Forestry, Horticulture, Fishery, Domestic Science, Nutrition
    Notes: Abstract The relation and collaboration of human and animal medicine had its ups and downs throughout history. The interaction between these two disciplines has been especially fruitful in the broad areas of patho-physiology and of epidemiology. An exploration of the interaction between the two disciplines, using historical and contemporary examples in comparative medicine, zoonoses, zooprophylaxis, and human-animal bond, reveals that a better understanding of animal and human disease, as well as societal changes such as interest in non-conventional medicine, are leading to a broader concept of one medicine that includes animal and human medicine as well as social and other sciences.
    Type of Medium: Electronic Resource
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  • 2
    ISSN: 1572-9699
    Keywords: ABC-transporter ; decarboxylation ; energetics ; lactic acid bacteria ; multidrug resistance ; secondary transport
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Abstract Lactic acid bacteria play an essential role in many food fermentation processes. They are anaerobic organisms which obtain their metabolic energy by substrate phosphorylation. In addition three secondary energy transducing processes can contribute to the generation of a proton motive force: proton/substrate symport as in lactic acid excretion, electrogenic precursor/product exchange as in malolactic and citrolactic fermentation and histidine/histamine exchange, and electrogenic uniport as in malate and citrate uptake in Leuconostoc oenos. In several of these processes additional H+ consumption occurs during metabolism leading to the generation of a pH gradient, internally alkaline. Lactic acid bacteria have also developed multidrug resistance systems. In Lactococcus lactis three toxin excretion systems have been characterized: cationic toxins can be excreted by a toxin/proton antiport system and by an ABC-transporter. This cationic ABC-transporter has surprisingly high structural an d functional analogy with the human MDR1-(P-glycoprotein). For anions an ATP-driven ABC-like excretion systems exist.
    Type of Medium: Electronic Resource
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