ISSN:
1434-193X
Keywords:
Glycosphinogolipids
;
Cerebrosides
;
Gangliosides
;
Sea cucumber
;
Cucumaria echinata
;
Chemistry
;
General Chemistry
Source:
Wiley InterScience Backfile Collection 1832-2000
Topics:
Chemistry and Pharmacology
Notes:
Five cerebrosides, CE-1-1, CE-1-2, CE-1-3, CE-3-1, and CE-3-2, and a ganglioside molecular species CG-1 have been obtained from the less polar and polar fractions, respectively, of the chloroform/methanol extract of the sea cucumber Cucumaria echinata. The structures of these glycosphingolipids have been determined on the basis of chemical and spectroscopic evidence. The cerebrosides show lethality toward brine shrimps. On the other hand, the ganglioside CG-1 exhibits neuritogenic activity toward the rat pheochromocytoma cell line, PC-12 cells.
Type of Medium:
Electronic Resource
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