ISSN:
1573-4935
Keywords:
thyrotropin
;
TSH
;
TSH receptor
;
Graves'
;
isoelectric focusing
Source:
Springer Online Journal Archives 1860-2000
Topics:
Biology
,
Chemistry and Pharmacology
Notes:
Abstract The water soluble A subunit of the human TSH receptor has been shown to have an isoelectric point of 5. As both TSH and TSH receptor antibodies have isoelectric points in the region of 8–10, charge-charge interactions must be of major importance in the binding of hormone or antibody to the TSH receptor A subunit.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF01114764
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