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  • Articles  (3)
  • breast cancer  (2)
  • Alberta  (1)
  • Springer  (3)
  • 1995-1999  (1)
  • 1985-1989  (2)
  • 1965-1969
  • 1920-1924
  • 1905-1909
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  • Articles  (3)
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  • Springer  (3)
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  • 1995-1999  (1)
  • 1985-1989  (2)
  • 1965-1969
  • 1920-1924
  • 1905-1909
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  • 1
    Electronic Resource
    Electronic Resource
    Cooking Oil: A Home Fire Hazard in Alberta, Canada (1997)
    Springer
    Fire technology 33 (1997), S. 140-166 
    Details
    ISSN: 1572-8099
    Keywords: Canada ; Alberta ; cooking equipment ; cooking oil ; fire injuries ; smoke point ; flash point ; fire hazard ; fire statistics ; prevention
    Source: Springer Online Journal Archives 1860-2000
    Topics: Architecture, Civil Engineering, Surveying
    Notes: Abstract This paper begins with a brief statistical analysis to establish the significant contribution of cooking equipment fires to fire losses and injuries in Canadian homes. Due to lack of comprehensive fire loss data for Canadian homes, further analysis is focused on Alberta data. The most frequent ignition scenario, based on a top-down analysis of Alberta home fires, was the ignition of overheated cooking oil in pots, deep-fat fryers, or pans heated on stove tops. These fires also accounted for the majority of home fire injuries. Fire characteristics of cooking oils, which point to the importance of maintaining oil temperatures below their flash points, and thermostatically controlled deep-fat fryers as the best available solution to the problem are discussed.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1023/A:1015395001403
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    Paper (German National Licenses)
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  • 2
    Electronic Resource
    Electronic Resource
    Phase I clinical trial of doxorubicin and iproplatin combination chemotherapy in patients with breast cancer (1989)
    Springer
    Investigational new drugs 7 (1989), S. 189-193 
    Details
    ISSN: 1573-0646
    Keywords: doxorubicin ; iproplatin ; breast cancer
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology , Medicine
    Notes: Summary Forty-eight patients with advanced breast cancer were treated in a disease-specific phase I trial of doxorubicin and iproplatin combination chemotherapy. The doses of doxorubicin ranged between 30 and 50 mg/m2, and the doses of iproplatin ranged between 150 and 250 mg/m2. Myelosuppression was observed at all levels, but was dose-limiting at the highest level. In addition, nausea, diarrhea and malaise were prominent toxicities. Neither cardiac nor renal toxicity was encountered. Nine of 26 (35%) of previously untreated patients, and 5 of 22 (23%) previously treated patients demonstrated partial or complete responses. Although this combination possesses therapeutic activity, given its toxicities, further evaluation of doxorubicin in combination with iproplatin is not recommended.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00170856
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    Paper (German National Licenses)
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  • 3
    Electronic Resource
    Electronic Resource
    Clinical trial of iproplatin (cis-dichloro-trans-dihydroxy-bis-isopropylamine platinum IV, CHIP) in patients with advanced breast cancer (1988)
    Springer
    Investigational new drugs 6 (1988), S. 87-91 
    Details
    ISSN: 1573-0646
    Keywords: breast cancer ; Iproplatin ; CHIP ; phase II study
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology , Medicine
    Notes: Summary Twenty-five women with advanced breast cancer were treated in a phase II trial of iproplatin 275 mg/m2 administered intravenously every 4 weeks. All patients had measurable or evaluable indicator lesions, and had undergone treatment with no more than one previous chemotherapy regimen, including adjuvant chemotherapy. Two of the twenty-four evaluable patients (8%) experienced major therapeutic responses. One patient had a complete regression of pulmonary nodules lasting 18 + months; another had a partial regression of metastatic disease in the liver (4 months). The inevaluable patient was ineligible for the study because of previous radiation to the indicator lesions on her chest wall; nonetheless, she experienced a 10 month partial regression of those nodules. Myelosuppression was generally dose limiting; thrombocytopenia was more profound, but leukopenia was more prolonged. Nausea, vomiting, diarrhea, and general malaise were prominent toxicities, and led to discontinuation of therapy in 4 patients. Iproplatin has limited activity in previously treated women with advanced breast cancer.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00195365
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