ISSN:
1573-1111
Keywords:
inclusion compounds
;
cholic acid
;
benzophenone
;
chiral conformations
Source:
Springer Online Journal Archives 1860-2000
Topics:
Chemistry and Pharmacology
Notes:
Abstract The 2 : 1 cholic acid – benzophenone clathratecrystallizes in the space group P2_1 withthe unit-cell parameters a = 25.498(6),b = 7.942(1), c = 28.309(6) Å,β = 101.85(2)°. There are four symmetricallyindependent host molecules in the unit cell: two ofthem with the steroidal side chain assuminggauche and the remaining two with the side chain in thetrans conformation. Pairs of the host moleculesadopting similar conformations alternate along the[201] direction of the bilayer. The guestmolecules are accommodated in two crystallographicallyindependent but topologically similar channelsrunning parallel to [010]. Benzophenone molecules aredisordered and included in each channel in twodifferent conformations.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1023/A:1008142919081
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