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  • Springer  (126)
  • American Geophysical Union  (99)
  • Blackwell Publishing Ltd  (37)
  • Macmillian Magazines Ltd.  (28)
  • American Institute of Physics (AIP)
  • 2000-2004  (311)
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  • 1
    Electronic Resource
    Electronic Resource
    Metal substitution in transferrins: specific binding of cerium(IV) revealed by the crystal structure of cerium-substituted human lactoferrin (2000)
    Springer
    JBIC 5 (2000), S. 692-698 
    Details
    ISSN: 1432-1327
    Keywords: Metal substitution Cerium binding Lactoferrin Crystal structure Transferrin
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Chemistry and Pharmacology
    Notes: Abstract. Proteins of the transferrin family play a key role in iron homeostasis through their extremely strong binding of iron, as Fe3+. They are nevertheless able to bind a surprisingly wide variety of other metal ions. To investigate how metal ions of different size, charge and coordination characteristics are accommodated, we have determined the crystal structure of human lactoferrin (Lf) complexed with Ce4+. The structure, refined at 2.2 Å resolution (R=20.2%, R free=25.7%) shows that the two Ce4+ ions occupy essentially the same positions as do Fe3+, and that the overall protein structure is unchanged; the same closed structure is formed for Ce2Lf as for Fe2Lf. The larger metal ion is accommodated by small shifts in the protein ligands, made possible by the presence of water molecules adjacent to each binding site. The two Ce4+ sites are equally occupied, indicating that the known difference in the pH-dependent release of Ce4+ arises from a specific protonation event, possibly of the His ligand in one of the binding sites. Comparing the effects of binding Ce4+ with those for the binding of other metal ions, we conclude that the ability of transferrins to accommodate metal ions other than Fe3+ depends on an interplay of charge, size, coordination and geometrical preferences of the bound metal ion. However, it is the ability to accept the six-coordinate, approximately octahedral, site provided by the protein that is of greatest importance.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s007750000157
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  • 2
    Electronic Resource
    Electronic Resource
    RESURRECTION OF MESOPLODON TRAVERSII (GRAY, 1874), SENIOR SYNONYM OF M. BAHAMONDI REYES, VAN WAEREBEEK, CÁRDENAS AND YÁÑEZ, 1995 (CETACEA: ZIPHIIDAE) (2002)
    Oxford, UK : Blackwell Publishing Ltd
    Marine mammal science 18 (2002), S. 0 
    Details
    ISSN: 1748-7692
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Biology
    Notes: Mesoplodon traversii (Gray, 1874) is shown to be a senior synonym of the recently described beaked whale Mesoplodon hahamondi Reyes et al., 1995 on the basis of a phylogenetic analysis of mitochondrial DNA control region sequences. The mandible and teeth of M. traversii, first reported in 1873 by Hector as Dolichodon layardii. are redescribed. The species can be distinguished by features of the calvaria; including the large jugal, broad rostrum, and small distance between premaxillary foramina. The male teeth, which are large and spade-shaped with a strong terminal denticle, are also diagnostic. M. traversii is known only from Pitt Island and White Island, New Zealand and Robinson Crusoe Island, Juan Fernandez Archipelago, Chile.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1748-7692.2002.tb01062.x
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  • 3
    Electronic Resource
    Electronic Resource
    A NEW SPECIES OF BEAKED WHALE MESOPLODON PERRINI SP. N. (CETACEA: ZIPHIIDAE) DISCOVERED THROUGH PHYLOGENETIC ANALYSES OF MITOCHONDRIAL DNA SEQUENCES (2002)
    Oxford, UK : Blackwell Publishing Ltd
    Marine mammal science 18 (2002), S. 0 
    Details
    ISSN: 1748-7692
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Biology
    Notes: Mesoplodon perrini, a new species of beaked whale is described on the basis of five animals stranded on the coast of California (between 32°55′N, 117°15′W and 36°37′N, 121°55′W) from May 1975 to September 1997. Four of these animals were initially identified as Hector's beaked whales M. hectori based on cranial morphology (Mead 1981). A fifth specimen was initially identified as a neonate Cuvier's beaked whale Ziphius cavirostris based on external features. These specimens were first recognized as representatives of an undescribed species through phylogenetic analysis of mitochondrial (mt) DNA control region and cytochrome b sequence data. Although similar morphologically, the genetic data do not support a close evolutionary relationship between M. perrini and M. hectori. Instead, these data suggest a possible sister species relationship with the lesser beaked whale M. peruvianus. Sightings of two small beaked whales off California in the 1970s which were tentatively identified as M. hectori are also likely to be M. perrini. We suggest that M. hectori is confined to the Southern Hemisphere, while M. perrini is known to date only from the North Pacific.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1748-7692.2002.tb01061.x
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  • 4
    Electronic Resource
    Electronic Resource
    Mae mediates MAP kinase phosphorylation of Ets transcription factors in Drosophila (2001)
    [s.l.] : Macmillian Magazines Ltd.
    Nature 411 (2001), S. 330-334 
    Details
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] The evolutionarily conserved Ras/mitogen-activated protein kinase (MAPK) cascade is an integral part of the processes of cell division, differentiation, movement and death. Signals received at the cell surface are relayed into the nucleus, where MAPK phosphorylates and thereby modulates the ...
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1038/35077122
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  • 5
    Electronic Resource
    Electronic Resource
    Technical Opportunities for International Collaborations by the U.S. Fusion Program (2000)
    Springer
    Journal of fusion energy 19 (2000), S. 65-79 
    Details
    ISSN: 1572-9591
    Keywords: Fusion energy ; international collaboration
    Source: Springer Online Journal Archives 1860-2000
    Topics: Energy, Environment Protection, Nuclear Power Engineering
    Notes: Abstract This report was prepared by a Working Group at the request of the U.S. Department of Energy, Office of Fusion Energy Sciences in 1997. The report addresses technical opportunities for mutually beneficial collaboration between the United States and other international fusion research programs. A number of outstanding opportunities are discussed.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1023/A:1012281826821
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  • 6
    Electronic Resource
    Electronic Resource
    Particle transport in DIII-D discharges with internal regions of enhanced confinement and counter injected neutral beams (2001)
    [S.l.] : American Institute of Physics (AIP)
    Physics of Plasmas 8 (2001), S. 1565-1572 
    Details
    ISSN: 1089-7674
    Source: AIP Digital Archive
    Topics: Physics
    Notes: An analysis of experimentally measured particle transport in tokamak plasmas with negative central magnetic shear is presented. The analysis is presented in terms of a simple model for turbulent transport which allows the separation of diagonal and off diagonal terms and allows the direct comparison of particle and energy transport. Comparing the measured fluxes to the fluxes predicted by a simple quasi analytical model which specifies a relation between the diagonal and off diagonal terms allows an understanding of the reason for the difference between energy and particle fluxes. In the center of discharges with a region of enhanced confinement (or internal transport barrier), the ion thermal diffusivity becomes small and comparable to neoclassical values and the particle diffusivity also becomes small and approaches the neoclassical values. © 2001 American Institute of Physics.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1063/1.1358311
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  • 7
    Electronic Resource
    Electronic Resource
    Decay of the daughter electromagnetic wave driven by stimulated Raman scattering into two Langmuir waves (2000)
    [S.l.] : American Institute of Physics (AIP)
    Physics of Plasmas 7 (2000), S. 2759-2762 
    Details
    ISSN: 1089-7674
    Source: AIP Digital Archive
    Topics: Physics
    Notes: Much attention has been focused on the saturation of stimulated Raman scattering by the decay of its daughter waves. This research has almost exclusively dealt with the decay of the daughter Langmuir wave into secondary Langmuir waves and ion acoustic waves. In this Letter, the decay of the Raman driven electromagnetic wave into two Langmuir waves, two-plasmon decay, is discussed for the first time. It is shown that based on the stimulated Raman scattering reflectivity levels measured in experiments, this instability should be present in current laser–plasma experiments. In addition, experimental signatures of this process are discussed. © 2000 American Institute of Physics.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1063/1.874174
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  • 8
    Electronic Resource
    Electronic Resource
    Effect of rotation on H-mode transport in DIII–D via changes in the E×B velocity shear (2002)
    [S.l.] : American Institute of Physics (AIP)
    Physics of Plasmas 9 (2002), S. 128-136 
    Details
    ISSN: 1089-7674
    Source: AIP Digital Archive
    Topics: Physics
    Notes: The effect of rotation on the heat and particle transport is measured in the DIII–D tokamak [Fusion Technol. 8, 441 (1985)] for high-confinement mode (H-mode) plasmas with edge localized modes. In a novel experiment, transport is compared for nearly identical scans of the relative gyroradius in co- and counter-rotating plasmas. Since the plasma profiles are the same, the difference in the transport scaling can be attributed to changes in the sheared E×B flow caused by the shift in the toroidal plasma velocity. The ion heat and particle transport are found to be sensitive to the change in the rotation direction and magnitude whereas the electron heat transport is not. Simulations using a gyroLandau-fluid drift wave transport model show that the variation in the ion heat transport for co/counter rotation is due to changes in the E×B shear stabilization, but the electrons appear to be governed by a different transport mechanism. © 2002 American Institute of Physics.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1063/1.1421077
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  • 9
    Electronic Resource
    Electronic Resource
    Sustained rotational stabilization of DIII-D plasmas above the no-wall beta limit : Review,Tutorial and Invited Papers from the 43rd Annual Meeting of the APS Division of Plasma Physics (2002)
    [S.l.] : American Institute of Physics (AIP)
    Physics of Plasmas 9 (2002), S. 1997-2005 
    Details
    ISSN: 1089-7674
    Source: AIP Digital Archive
    Topics: Physics
    Notes: Sustained stabilization of the n=1 kink mode by plasma rotation at beta approaching twice the stability limit calculated without a wall has been achieved in DIII-D by a combination of error field reduction and sufficient rotation drive. Previous experiments have transiently exceeded the no-wall beta limit. However, demonstration of sustained rotational stabilization has remained elusive because the rotation has been found to decay whenever the plasma is wall stabilized. Recent theory [Boozer, Phys. Rev. Lett. 86, 5059 (2001)] predicts a resonant response to error fields in a plasma approaching marginal stability to a low-n kink mode. Enhancement of magnetic nonaxisymmetry in the plasma leads to strong damping of the toroidal rotation, precisely in the high-beta regime where it is needed for stabilization. This resonant response, or "error field amplification" is demonstrated in DIII-D experiments: applied n=1 radial fields cause enhanced plasma response and strong rotation damping at beta above the no wall limit but have little effect at lower beta. The discovery of an error field amplification has led to sustained operation above the no-wall limit through improved magnetic field symmetrization using an external coil set. The required symmetrization is determined both by optimizing the external currents with respect to the plasma rotation and by use of feedback to detect and minimize the plasma response to nonaxisymmetric fields as beta increases. Ideal stability analysis and rotation braking experiments at different beta values show that beta is maintained 50% higher than the no wall stability limit for durations greater than 1 s, and approaches beta twice the no-wall limit in several cases, with steady-state rotation levels. The results suggest that improved magnetic-field symmetry could allow plasmas to be maintained well above no-wall beta limit for as long as sufficient torque is provided. © 2002 American Institute of Physics.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1063/1.1446036
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  • 10
    Electronic Resource
    Electronic Resource
    Comparison of particle confinement in the high confinement mode plasmas with the edge localized mode of the Japan Atomic Energy Research Institute Tokamak-60 Upgrade and the DIII-D tokamak (2001)
    [S.l.] : American Institute of Physics (AIP)
    Physics of Plasmas 8 (2001), S. 1607-1611 
    Details
    ISSN: 1089-7674
    Source: AIP Digital Archive
    Topics: Physics
    Notes: Particle confinement was compared for the high confinement mode plasmas with the edge localized mode in the Japan Atomic Energy Research Institute Tokamak-60 Upgrade (JT-60U) [S. Ishida, JT-60 Team, Nucl. Fusion 39, 1211 (1999)] and the DIII-D tokamak [J. L. Luxon et al., Plasma Physics and Controlled Nuclear Fusion Research 1986 (International Atomic Energy Agency, Vienna, 1987), Vol. 1, p. 159] considering separate confinement times for particles supplied by neutral beam injection (NBI) (center fueling) and by recycling and gas-puffing (edge fueling). Similar dependence on the NBI power was obtained in JT-60U and DIII-D. The particle confinement time for center fueling in DIII-D was smaller by a factor of 4 in the low density discharges and by a factor of 1.8 in the high density discharges than JT-60U scaling, respectively, suggesting the stronger dependence on the density in DIII-D. The particle confinement time for edge fueling in DIII-D was comparable with JT-60U scaling in the low density discharges. However, it decreased to a much smaller value in the high density discharges. © 2001 American Institute of Physics.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1063/1.1362295
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