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  • Springer  (117)
  • Blackwell Science Ltd  (3)
  • 2000-2004  (106)
  • 1965-1969  (14)
  • 1950-1954
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  • 1
  • 2
    Publication Date: 2003-07-01
    Print ISSN: 0015-5632
    Electronic ISSN: 1874-9356
    Topics: Biology
    Published by Springer
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  • 3
    Publication Date: 2003-03-01
    Print ISSN: 0015-5632
    Electronic ISSN: 1874-9356
    Topics: Biology
    Published by Springer
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  • 4
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Science Ltd
    Autonomic & autacoid pharmacology 23 (2003), S. 0 
    ISSN: 1474-8673
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Chemistry and Pharmacology , Medicine
    Notes: 1 This study used contractility methods with the portal veins of 5- and 14-week-old Wistar–Kyoto normotensive rats (WKY) and spontaneously hypertensive rats (SHRs). The SHRs are prehypertensive at 5 weeks. 2 The first part of our study was to determine whether the responsiveness to isoprenaline and forskolin was altered in the maturation of portal veins from normo- and prehypertensive rats. The responses to forskolin were similar on the portal veins of 5- and 14-week-old WKY and SHRs. 3 The sensitivity and maximum responses to isoprenaline were similar on portal veins of 5- and 14-week-old WKY. The sensitivity and maximum responses to isoprenaline were lower on the portal veins of 5-week-old SHRs (pD2 = 8.25, maximum = 85%) than age-matched WKY (pD2 = 8.79, maximum = 96%); these differences are not caused by hypertension. At 14 weeks, the sensitivity was similar (WKY pD2 = 8.74, SHR pD2 = 8.65) but the maximum responses to isoprenaline were lower on the portal veins SHRs (77%) than WKY (97%). Thus, the sensitivity to isoprenaline increases with the development of hypertension in the SHR portal vein. 4 The second part of the study was to determine whether the affinity for isoprenaline at β2-adrenoceptors and the fractional β2-adrenoceptor occupancy–response relationships on the portal vein were altered in maturation from normo- and pre-hypertensive rats. The effects of bromoacetylalprenololmenthane (BAAM), an irreversible β-adrenoceptor blocker, on the isoprenaline responses of 5- and 14-week-old WKY and SHRs were studied. Maturation of the WKY portal vein between 5 and 14 weeks was associated with a loss of affinity for isoprenaline (from pKA of 7.13 to 7.87), and increase in β2-adrenoceptor reserve (from 72 to 92% at the 95% response). There were similar affinity and reserve findings in the maturation of the SHR portal vein. Thus, there are major changes in β2-adrenoceptor structure and reserve in maturation on the portal vein that are irrespective of the development of hypertension.
    Type of Medium: Electronic Resource
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  • 5
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Science Ltd
    Plant, cell & environment 26 (2003), S. 0 
    ISSN: 1365-3040
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Biology
    Notes: A wound-inducible cDNA, ipomoelin (IPO) was isolated from the subtraction library of sweet potato (Ipomoea batatas cv. Tainung 57) and used as a molecular probe to investigate the transduction pathway of wounding signal within plant cells. Following mechanical wounding of the leaves of sweet potato, IPO mRNA accumulation peaked at 6 h and then continuously declined. However, IPO gene expression in the apical unwounded leaves began at 6 h after wounding and continued for a further 10 h. Besides mechanical wounding, methyl jasmonate (MeJA) was identified as a signal transducer leading to the accumulation of IPO mRNA. Treatment with salicylic acid reduced the production of IPO mRNA, further supporting the involvement of the octadecanoid pathway in the signal transduction of wounding in sweet potato. In addition, ethylene was involved in the signal pathway and induced the expression of the IPO gene. Furthermore, the application of okadaic acid, a protein phosphatase inhibitor, blocked the accumulation of IPO mRNA induced by MeJA or ethylene, indicating that activation of the IPO gene by both MeJA and ethylene was via dephosphorylated proteins. The presence of a calcium ion chelator or channel blockers also inhibited the expression of the IPO gene after wounding. However, investigation by confocal scanning microscopy further pointed out that mechanical wounding rather than the application of MeJA induced the accumulation of the calcium ion. These results may indicate that the calcium ion is also involved in the activation of IPO mRNA. In addition, wounding signals the accumulation of calcium ion first and then stimulates the biosynthesis of MeJA in sweet potato. Hence, the reaction sequence of signal transducers, including the calcium ion, MeJA and protein kinase/phosphatase, in the wounding signalling pathway of sweet potato is suggested in this report.
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  • 6
    Electronic Resource
    Electronic Resource
    PO Box 1354, 9600 Garsington Road, Oxford OX4 2XG, UK. : Blackwell Science Ltd
    Fatigue & fracture of engineering materials & structures 27 (2004), S. 0 
    ISSN: 1460-2695
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Notes: It is well known that microcracking in brittle materials results in a reduction of the stress intensity factor (SIF) and energy release rate (ERR). The reduced SIF or ERR represents crack tip shielding which is of significant interest to micromechanics and material science researchers. However, the effect of microcracking on the SIF and ERR is a complicated subject even for isotropic homogeneous materials, and becomes much more formidable in case of interface cracks in bonded dissimilar solids. To unravel the micromechanics of interface crack tip shielding in bonded dissimilar anisotropic solids, an interface crack interacting with arbitrarily oriented subinterface microcracks in bonded dissimilar anisotropic materials is studied. After deducing the fundamental solutions for a subinterface crack under concentrated normal and tangential tractions, the present interaction problem is reduced to a system of integral equations which is then solved numerically. A J-integral analysis is then performed with special attention focused on the J2-integral in a local coordinate system attached to the microcracks. Theoretical and numerical results reassert the conservation law of the J-integral derived for isotropic materials1,2 also to be valid for bonded dissimilar anisotropic materials. It is further concluded that there is a wastage when the remote J-integral transmits across the microcracking zone from infinity to the interface macrocrack tip. In order to highlight the influence of microstructure on the interfacial crack tip stress field, the crack tip SIF and ERR in several typical cases are presented. It is interesting to note that the Mode I SIF at the interface crack tip is quite different from the ERR in bonded dissimilar anisotropic materials.
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  • 7
    Electronic Resource
    Electronic Resource
    Springer
    Journal of polymer research 7 (2000), S. 257-266 
    ISSN: 1572-8935
    Keywords: Poly(ether sulfone) ; Epoxy resin ; Physical aging ; DSC
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology , Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics , Physics
    Notes: Abstract The physical aging process of 4-4′-diaminodiphenylsulfone (DDS) cured diglycidyl ether bisphenol-A (DGEBA) blended with various molecular weights of poly(ether sulfone) (PES; Mn = 28,600, 10,600, and 6,137) was studied by DSC. For DGEBA/DDS system blended with a low MW PES-3 (Mn = 6,137), no phase separation of the polymer blend and only one enthalpic relaxation process due to physical aging was observed. Since the high MW PES-1 (Mn = 28,600) had a Tg close to that of fully cured DGEBA/DDS, the fully cured DGEBA/DDS/PES-1 blend had a broader glass transition than a neat DGEBA/DDS system. However, the DSC results showed two enthalpic relaxation processes due to the physical aging of PES-rich and cured epoxy-rich phases as the material was aged at 155 °C (30 °C below Tg). Since the Tgs of PES-1-rich and epoxy-rich phases overlapped with each other, the enthalpic relaxation processes corresponding to each phase coupled to each other in the earlier stage of physical aging. The medium MW PES-2 (Mn = 10,600) has a much lower Tg than that of fully cured DGEBA/DDS, two well separated Tgs were observed for the cured DGEBA/DDS/PES-2 blend, indicating the cured epoxy was immiscible with PES. Aging the polymer blend at 155 °C (24 °C below Tg1 of the PES-2-rich phase and 53 °C below Tg2 of the epoxy-rich phase) produced two well separated relaxation processes due to PES-2-rich and epoxy-rich phases. The experimental results suggested that aging the polymer blend at a suitable temperature would improve the phase separation between PES-1-rich and epoxy-rich phases.
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  • 8
    Electronic Resource
    Electronic Resource
    Springer
    The European physical journal 220 (1969), S. 185-198 
    ISSN: 1434-601X
    Source: Springer Online Journal Archives 1860-2000
    Topics: Physics
    Notes: Abstract The effect of the single particle excitations on the spectra of muonic atoms with odd-mass nuclei is studied in the frame work of the unified model. The theoretical spectra are compared with the experimental ones and the excitation strengths of the nuclear states as well as the nuclear polarization due to the muon are calculated.
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  • 9
    Electronic Resource
    Electronic Resource
    Springer
    Applied physics 70 (2000), S. 475-478 
    ISSN: 1432-0649
    Keywords: PACS: 42.55.Rz
    Source: Springer Online Journal Archives 1860-2000
    Topics: Physics
    Notes: Abstract. A dual-wavelength continuous wave (cw) diode-end-pumped Nd:YVO4 laser that generates simultaneous laser action at the wavelengths 1064 nm and 1342 nm is demonstrated. The optimum oscillation condition for the simultaneous dual-wavelength operation in a diode-end-pumped solid-state laser has been derived. The relationship between the laser cavity and the output stability is also studied. Experimental results show that the stability of the output power at the two wavelengths could be enhanced by use of a three-mirror cavity.
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  • 10
    Electronic Resource
    Electronic Resource
    Springer
    Archive of applied mechanics 70 (2000), S. 625-634 
    ISSN: 1432-0681
    Keywords: Key words Composite material, damage, M-integral, interaction, microcrack, potential energy
    Source: Springer Online Journal Archives 1860-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Notes: Summary  This paper presents an M-integral analysis for the microcracked anisotropic composite materials. By using an elementary solution derived for a single finite crack subjected to a concentrated force on crack faces, the problem of strong interacting, arbitrarily oriented and located microcracks in an anisotropic composite materials is reduced to a system of Fredholm integral equations. The crack-tip fracture parameters, such as the stress intensity factors, are evaluated from a numerical solution of the system of integral equations. Its dependence on the coordinate system, calculation, and physical interpretation of the M-integral are discussed in the interaction problem. Finally, a numerical example of the damage evaluation by the M-integral analysis is given.
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