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  • Articles  (3)
  • System identification  (2)
  • 42.55
  • Bone
  • Coleoptera
  • Springer  (3)
  • Annual Reviews
  • Springer Science + Business Media
  • 2000-2004
  • 1980-1984  (3)
  • Technology  (3)
  • 1
    Electronic Resource
    Electronic Resource
    Assessment of cerebrospinal fluid compliance and outflow resistance: Analysis of steady-state response to sinusoidal input (1983)
    Springer
    Annals of biomedical engineering 11 (1983), S. 551-561 
    Details
    ISSN: 1573-9686
    Keywords: Sinusoidal ; CSF ; Cerebrospinal fluid ; System identification
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine , Technology
    Notes: Abstract Cerebrospinal fluid dynamics have been studied in the past by analyses of responses to bolus, constant rate or constant pressure inputs. In this study, we present a method for analyzing CSF pressure responses to sinusoidal variation in the infusion rate. Infusion of artificial CSF into the cisterna magna of adult rats was modulated sinusoidally between 0 and 30 μl/min. The resulting sinusoidal variation in intracranial pressure was recorded on a strip chart recorder simultaneously with the infusion rate signal. The two signals were analyzed for peak-to-peak variation, mean value, and phase shift for input frequencies in the range of 0.0015 to 0.01 Hz (0.00942 to 0.0628 radians/sec). The system was analyzed at each mean infusion rate as a parallel resistance and compliance with a first order linear model. The resistance to CSF outflow was determined as the change in mean steady-state pressure divided by the change in mean infusion rate. The compliance was then obtained from the frequency dependent phase shift between input and output using the first-order linear model. Resistance values were lower for higher average infusion rates consistent with our previous work, while compliance remained constant over the measured pressure range.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02364084
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  • 2
    Electronic Resource
    Electronic Resource
    Model utility in the study of cardiorespiratory control (1983)
    Springer
    Annals of biomedical engineering 11 (1983), S. 337-348 
    Details
    ISSN: 1573-9686
    Keywords: Exercise ; Input design ; System identification
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine , Technology
    Notes: Abstract This study investigates the utility of differing modeling approaches to the study of cardiorespiratory control. Models are classified in terms of intended purpose. A structural model predicts behavior based on a hypothetical physiological structure. An empirical model summarizes observed behavior. A functional model attempts to relate physiological structure to observed behavior. Models from the literature for exercising man illustrate these concepts and motivate the importance of experimental design in terms of the dynamic variation of a work-rate input.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02363291
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  • 3
    Electronic Resource
    Electronic Resource
    The human tibia: Static testing in bending by anin vivo method (1982)
    Springer
    Annals of biomedical engineering 10 (1982), S. 281-294 
    Details
    ISSN: 1573-9686
    Keywords: Tibia ; Strength ; Bone ; Elastic modulus
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine , Technology
    Notes: Abstract We have developed a method for static testing of the human tibia in bending in the living subject, and fabricated a prototype device for carrying it out. Model testing indicates that the device and model system are inherently accurate and reliable. However, the biological system is more complex, and while more than 200 tests have been conducted with perfect safety, the variability of replicate tests suggests that the method does not yet have general clinical utility. In some subjects, that variance is relatively small, possibly because they are more relaxed and perhaps also for anatomical reasons. In two subjects, postmortem tests corresponded very well with antemortem tests on the tibiometer. We conclude that with further refinements the method may have clinical potential, if only in carefully selected subjects.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02367309
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